Major increase in Type 1 diabetes: No support for the Accelerator Hypothesis

Diabetic Medicine

Volumn 25, Issue 3, 2008, Pages 376-377

  Wilkin, T ^a  

^a DERRIFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACCELERATOR HYPOTHESIS; AUSTRALIA; BODY MASS; CHILD; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; HYPOTHESIS; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LETTER; ONSET AGE; PATHOPHYSIOLOGY; RISK ASSESSMENT;

AGE OF ONSET; BODY MASS INDEX; CHILD; DIABETES MELLITUS, TYPE 1; HUMANS; INSULIN RESISTANCE;

EID: 40049102024     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2007.02344.x     Document Type: Letter

References (11)

1. Wilkin TJ. The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia 2001 44 : 914 922.
2. Kibirige M, Metcalf B, Renuka R, Wilkin TJ. Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1diabetes. Diabetes Care 2003 26 : 2865 2870.
3. Betts P, Mulligan J, Ward P, Smith B, Wilkin TJ. Increasing body weight predicts the earlier onset of insulin-dependant diabetes in childhood: testing the 'accelerator hypothesis' (2). Diabet Med 2005 22 : 144 151.
4. Knerr I, Wolf J, Reinehr T, Stachow R, Grabert M, Schober E et al. DPV Scientific Initiative of Germany and Austria. The 'accelerator hypothesis': relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9248 German and Austrian children with type 1 diabetes mellitus. Diabetologia 2005 48 : 2501 2504.
5. Kordonouri O, Hartmann R. Higher body weight is associated with earlier onset of Type 1 diabetes in children: confirming the 'Accelerator Hypothesis'. Diabet Med 2005 22 : 1783 1784.
6. Dabelea D, D'Agostino RB Jr., Mayer-Davis EJ, Pettitt DJ, Imperatore G, Dolan LM et al. SEARCH for Diabetes in Youth Study Group. Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes. Diabetes Care 2006 29 : 290 294.
7. O'Connell MA, Donath S, Cameron FJ. Major increase in Type 1 diabetes - no support for the Accelerator Hypothesis. Diabet Med 2007 24 : 920 923.
8. O'Connell MA, Donath S, Cameron FJ. Major increase in Type 1 diabetes: no support for the Accelerator Hypothesis. Diabetic Med 2007 24 : 920 923.
9. Jeffery AN, Alba S, Murphy MJ, Voss LD, Metcalf BS, Hosking J et al. The behaviour of insulin resistance and its metabolic correlates in pre-pubertal children: a longitudinal study (EarlyBird 32). Diabetes Care 2007, epub ahead of print.
10. Porter JR, Barrett TG. Braking the Accelerator Hypothesis? Diabetologia 2004 47 : 352 353.
11. Dabelea D, D'Agostino RB, Mayer-Davis EJ, Pettitt DJ, Imperatore G, Dolan LM et al. for the SEARCH for Diabetes in Youth Study Group : Testing the Accelerator Hypothesis. Body size, beta-cell function and age at onset of type 1 (autoimmune) diabetes. Diabetes Care 2006 29 : 290 294.