Blockade of NMDA receptors pre-training, but not post-training, impairs object displacement learning in the rat

Brain Research

Volumn 1199, Issue , 2008, Pages 126-132

  Larkin, Aoife E ^a   Fahey, Briana ^a   Gobbo, Oliviero ^a   Callaghan, Charlotte K ^a   Cahill, Emma ^a   O'Mara, Shane M ^a   Kelly, Áine M ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

CPP; ERK; Hippocampus; NMDA; Spatial learning

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; HIPPOCAMPUS; LEARNING; MALE; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; TASK PERFORMANCE;

RATTUS;

EID: 40049097108     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.01.019     Document Type: Article

References (41)

1. Adams J.P. Sweatt J.D. Molecular psychology: roles for the ERK MAP kinase cascade in memory Annu. Rev. Pharmacol. Toxicol. 42 2002 135 163
2. Anderson M. O'Mara S.M. Activity of subicular units on a spatial and non-spatial version of an open-field object exploration task Exp. Brain Res. 159 2004 519 529
3. Atkins C.M. Selcher J.C. Petraitis J.J. Trzaskos J.M. Sweatt J.D. The MAPK cascade is required for mammalian associative learning Nat. Neurosci. 1 1998 602 609
4. Bannerman D.M. Rawlins J.N. Good M.A. The drugs don't work—or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-A-containing AMPA receptors to hippocampal-dependent memory Psychopharmacol. (Berlin). 188 2006 552 566
5. Berman D.E. Hazvi S. Rosenblum K. Seger R. Dudai Y. Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat J. Neurosci. 18 1998 10037 10044
6. Blum S. Moore A.N. Adams F. Dash P.K. A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory J. Neurosci. 19 1999 3535 3544
7. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein–dye binding Anal. Biochem. 72 1976 248 254
8. Butelman E.R. A novel NMDA antagonist, MK-801, impairs performance in a hippocampal-dependent spatial learning task Pharmacol. Biochem. Behav. 34 1986 13 16
9. Collingridge G.L. Kehl S.J. McLennan H. Excitatory amino acids in synaptic transmission in the Schaffer collateral–commissural pathway of the rat hippocampus J. Physiol. (London) 334 1983 33 46
10. de Lima M.N. Laranja D.C. Bromberg E. Roesler R. Scroder N. Pre- or post-training administration of the NMDA receptor blocker MK-801 impairs object recognition memory in rats Behav. Brain Res. 156 2005 139 143
11. Goldin M. Segal M. Protein kinase C and ERK involvement in dendritic spine plasticity in cultured rodent hippocampal neurons Eur. J. Neurosci. 17 2003 2529 2539
12. Gooney M. Shaw K. Kelly A. O'Mara S.M. Lynch M.A. Long-term potentiation and spatial learning are associated with increased phosphorylation of TrkB and extracellular signal-regulated kinase (ERK) in the dentate gyrus: evidence for a role for brain-derived neurotrophic factor Behav. Neurosci. 116 2002 455 463
13. Heale V. Harley C. MK-801 and AP5 impair acquisition, but not retention, of the Morris milk maze Pharmacol. Biochem. Behav. 36 1990 145 149
14. Hennigan A. Trotter C. Kelly A.M. Lipopolysaccharide impairs long-term potentiation and recognition memory and increases p75NTR expression in the rat dentate gyrus Brain Res. 1130 2007 158 166
15. Ivanov A. C. Pellegrino S. Rama Dumalska I. Salyha Y. Ben-Ari Y. Medina I. Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons J. Physiol. 572 2006 789 798
16. Jerram A.H. Smith P.F. Darlington C.L. A dose–response analysis of the behavioral effects of (+)MK-801 in guinea pig: comparison with CPP Pharmacol. Biochem. Behav. 53 1996 799 807
17. Kelly Á. Laroche S. Davis S. Activation of the MAP kinase pathway is necessary for the consolidation and reconsolidation of long-term recognition memory J. Neurosci. 23 2003 5354 5360
18. Kentros C. Hargreaves E. Hawkins R.D. Kandel E.R. Shapiro M. Muller R.V. Abolition of long-term stability of new hippocampal place cell maps by NMDA receptor blockade Science 280 1998 2121 2126
19. Kurino M. Fukunaga K. Ushio Y. Miyamoto E. Activation of mitogen-activated protein kinase in cultured rat hippocampal neurons by stimulation of glutamate receptors J. Neurochem. 65 1995 1282 1289
20. Lehmann J. Schneider J. McPherson S. Murphy D.E. Bernard P. Tsai C. Bennett D.A. Pastor G. Steele D.J. Boehm C. CPP, a selective N -methyl- d -aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo J. Pharmacol. Exp. Ther. 240 1987 737 746
21. Mandillo S. Rinaldi A. Oliverio A. Mele A. Repeated administration of phencyclidine, amphetamine and MK-801 selectively impairs spatial learning in mice: a possible model of psychotomimetic drug-induced cognitive deficits Behav. Pharmacol. 14 2003 533 544
22. McDonald R.J. Hong N.S. Craig L.A. Holahan M.R. Louis M. Muller R.U. NMDA-receptor blockade by CPP impairs post-training consolidation of a rapidly acquired spatial representation in rat hippocampus Eur. J. Neurosci. 22 2005 1201 1213
23. McLamb R.L. Williams L.R. Nanry K.P. Wilson W.A. Tilson H.A. MK-801 impedes the acquisition of a spatial memory task in rats Pharmacol. Biochem. Behav. 37 1990 41 45
24. Miserendino M.J.D. Sananes C.B. Melia K.R. Davis M. Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala Nature 345 1990 716 718
25. Mondadori C. Weiskrantz L. Buerki H. Petschke F. Fagg G.E. NMDA receptor antagonists can enhance or impair learning performance in animals Exp. Brain Res. 75 1989 449 456
26. Morris R.G. Anderson E. Lynch G.S. Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N -methyl- d -aspartate receptor antagonist, AP5 Nature 319 1986 774 776
27. Nadel L. Hardt O. The spatial brain Neuropsychology 18 2004 473 476
28. Norris C.M. Foster T.C. MK-801 improves retention in aged rats: implications for altered neural plasticity in age related memory deficits Neurobiol. Learn. Mem. 71 1999 194 206
29. Porter R.H. Cowburn R.F. Alasuzoff I. Briggs R.S. Roberts P.J. Heterogeneity of NMDA receptors labelled with [3H]3-((+−)-2-carboxypiperazin-4-yl) propyl-1-phosphonic acid ([3H]CPP): receptor status in Alzheimer's disease brains Eur. J. Pharmacol. 225 1992 195 201
30. Poucet B. Object exploration, habituation, and response to a spatial change in rats following septal or medial frontal cortical damage Behav. Neurosci. 103 1989 1009 1016
31. Rondi-Reig L. Libbey M. Eichenbaum H. Tonegawa S. CA1-specific N -methyl- d -aspartate receptor knockout mice are deficient in solving a nonspatial transverse patterning task Proc. Natl. Acad. Sci. U. S. A. 98 2001 3543 3548
32. Sargolini F. Roullet P. Oliverio A. Mele A. Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice Neurosci. 938 1999 55 67
33. Selcher J. Atkins C.M. Trzaskos J.M. Paylor R. Sweatt J.D. A necessity for MAP kinase activation in mammalian spatial learning Learn. Mem. 6 1999 478 490
34. Sweatt J.D. Mitogen-activated protein kinases in synaptic plasticity and memory Curr. Opin. Neurobiol. 14 2004 311 317
35. Tsien J.Z. Huerta P.T. Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory Cell, 87 1996 1327 1338
36. Ungerer A. Mathis C. Melan C. De Barry J. The NMDA receptor antagonists, CPP and gamma- l -glutamyl- l -aspartate, selectively block post-training improvement of performance in a Y-maze avoidance learning task Brain Res. 549 1991 59 65
37. Usiello A. Sargolini F. Roullet P. Ammassari-Teule M. Passino E. Oliverio A. Mele A. N -methyl- d -aspartate receptors in the nucleus accumbens are involved in detection of spatial novelty in mice Psychopharmacol. 137 1998 175 183
38. Valjent E. Corbille A.G. Bertran-Gonzalez J. Herve D. Girault J.A. Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference Proc. Natl. Acad. Sci. U. S. A. 103 2006 2932 2937
39. Weitlauf C. Honse Y. Auberson Y.P. Mishina M. Lovinger D.M. Winder D.G. Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation J. Neurosci. 25 2005 8386 8390
40. Zhu X.O. Brown M.W. Aggleton J.P. Neuronal signalling of information important to visual recognition memory in rat rhinal and neighbouring cortices Eur. J. Neurosci. 7 1995 753 765
41. Zhu X.O. Brown M.W. McCabe B.J. Aggleton J.P. Effects of the novelty or familiarity of visual stimuli on the expression of the immediate early gene c-fos in rat brain Neurosci. 69 1995 821 829