메뉴 건너뛰기




Volumn 53, Issue 4, 1996, Pages 799-807

A dose-response analysis of the behavioral effects of (+)MK-801 in guinea pig: Comparison with CPP

Author keywords

(+)MK 801; CPP; Guinea pig; NMDA antagonists; NMDA receptors

Indexed keywords

3 (2 CARBOXYPIPERAZIN 4 YL)PROLYL 1 PHOSPHONIC ACID; ANTICONVULSIVE AGENT; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG;

EID: 0029918950     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/0091-3057(95)02075-6     Document Type: Article
Times cited : (17)

References (32)
  • 1
    • 0023856682 scopus 로고
    • The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils
    • Boast, C. A.; Gerhardt, S. C.; Pastor, G.; Lehmann, J.; Etiene, P. E.; Liebman, J. M. The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils. Brain Res. 442:345-348; 1988.
    • (1988) Brain Res. , vol.442 , pp. 345-348
    • Boast, C.A.1    Gerhardt, S.C.2    Pastor, G.3    Lehmann, J.4    Etiene, P.E.5    Liebman, J.M.6
  • 2
    • 0343041871 scopus 로고
    • Glutamate and epilepsy: Theories and therapeutics
    • Calne, D. B. Glutamate and epilepsy: Theories and therapeutics. Neurology 44(Suppl. 8):S5-S6; 1994.
    • (1994) Neurology , vol.44 , Issue.SUPPL. 8
    • Calne, D.B.1
  • 3
    • 0025374552 scopus 로고
    • Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems
    • Carlsson, M.; Svensson, A. Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems. Pharmacol. Biochem. Behav. 36:45-50; 1990.
    • (1990) Pharmacol. Biochem. Behav. , vol.36 , pp. 45-50
    • Carlsson, M.1    Svensson, A.2
  • 4
    • 0024829451 scopus 로고
    • Excitatory amino acid receptors in the vertebrate central nervous system
    • Collingridge, G. L.; Lester, R. A. J. Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Revs. 40:143-210; 1989.
    • (1989) Pharmacol. Revs. , vol.40 , pp. 143-210
    • Collingridge, G.L.1    Lester, R.A.J.2
  • 5
    • 0023913251 scopus 로고
    • Biochemical and behavioral effects of sigma and PCP ligands
    • Contreras, P. C.; Contreras, M. L.; O'Donohue, T. L.; Lair, C. C. Biochemical and behavioral effects of sigma and PCP ligands. Synapse 2:240-243; 1988.
    • (1988) Synapse , vol.2 , pp. 240-243
    • Contreras, P.C.1    Contreras, M.L.2    O'Donohue, T.L.3    Lair, C.C.4
  • 6
    • 0025268452 scopus 로고
    • MK-801 reduced cerebral ischemic injury by inducing hypothermia
    • Corbett, D.; Evans, S.; Thomas, C.; Wang, D.; Jonas, R. A. MK-801 reduced cerebral ischemic injury by inducing hypothermia. Brain Res. 514:300-304; 1990.
    • (1990) Brain Res. , vol.514 , pp. 300-304
    • Corbett, D.1    Evans, S.2    Thomas, C.3    Wang, D.4    Jonas, R.A.5
  • 7
    • 0024827660 scopus 로고
    • The effects of N-methyl-D-aspartate antagonists on the development of vestibular compensation in the guinea pig
    • Darlington, C. L.; Smith, P. F. The effects of N-methyl-D-aspartate antagonists on the development of vestibular compensation in the guinea pig. Eur. J. Pharmacol. 174:273-278; 1989.
    • (1989) Eur. J. Pharmacol. , vol.174 , pp. 273-278
    • Darlington, C.L.1    Smith, P.F.2
  • 9
    • 0027163658 scopus 로고
    • The tolerometer: A fast, automated method for the measurement of righting reflex latency in chronic drug studies
    • Dingwall, B.; Reeve, B.; Hutchinson, M.; Smith, P. F.; Darlington, C. L. The tolerometer: A fast, automated method for the measurement of righting reflex latency in chronic drug studies. J. Neurosci. Methods 48:111-114; 1993.
    • (1993) J. Neurosci. Methods , vol.48 , pp. 111-114
    • Dingwall, B.1    Reeve, B.2    Hutchinson, M.3    Smith, P.F.4    Darlington, C.L.5
  • 10
    • 0028934737 scopus 로고
    • The N-methyl-D-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias
    • Ellison, G. The N-methyl-D-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias. Brain Res. Rev. 20:250-267; 1995.
    • (1995) Brain Res. Rev. , vol.20 , pp. 250-267
    • Ellison, G.1
  • 11
    • 0028925403 scopus 로고
    • MK-801-induced hyperactivity: Duration of effects in rats
    • Hargreaves, E. L.; Cain, D. P. MK-801-induced hyperactivity: Duration of effects in rats. Pharmacol. Biochem. Behav. 51:13-19; 1995.
    • (1995) Pharmacol. Biochem. Behav. , vol.51 , pp. 13-19
    • Hargreaves, E.L.1    Cain, D.P.2
  • 12
    • 0022930507 scopus 로고
    • Action of (3-(±)-2-carboxypiperazin-4-yl)-propyl-1 phosphonic acid (CPP): A new and highly potent antagonist of the N-methyl-D-aspartate receptor in the hippocampus
    • Harris, E. W.; Ganong, A. H.; Monaghan, J. C.; Watkins, J. C.; Cotman, C. W. Action of (3-(±)-2-carboxypiperazin-4-yl)-propyl-1 phosphonic acid (CPP): A new and highly potent antagonist of the N-methyl-D-aspartate receptor in the hippocampus. Brain Res. 383:174-180; 1986.
    • (1986) Brain Res. , vol.383 , pp. 174-180
    • Harris, E.W.1    Ganong, A.H.2    Monaghan, J.C.3    Watkins, J.C.4    Cotman, C.W.5
  • 13
    • 0024344248 scopus 로고
    • Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine
    • Hiramatsu, M.; Cho, A. K.; Nabeshima, T. Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine. Eur. J. Pharmacol. 166:359-366; 1989.
    • (1989) Eur. J. Pharmacol. , vol.166 , pp. 359-366
    • Hiramatsu, M.1    Cho, A.K.2    Nabeshima, T.3
  • 14
    • 0028258111 scopus 로고
    • Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: Evidence for glutamate hypothesis
    • Ishimaru, M.; Kurumaji, A.; Toru, M. Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: Evidence for glutamate hypothesis. Biol. Psychiatry 35:84-95; 1994.
    • (1994) Biol. Psychiatry , vol.35 , pp. 84-95
    • Ishimaru, M.1    Kurumaji, A.2    Toru, M.3
  • 15
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt, D. C.; Zukin, S. R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 148:1301-1308; 1991.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 16
    • 0023219059 scopus 로고
    • Noncompetitive antagonists of excitatory amino acid receptors
    • Kemp, J. A.; Foster, A. C.; Wong, E. H. F. Noncompetitive antagonists of excitatory amino acid receptors. Trends Neurosci. 10:294-298; 1987.
    • (1987) Trends Neurosci. , vol.10 , pp. 294-298
    • Kemp, J.A.1    Foster, A.C.2    Wong, E.H.F.3
  • 17
    • 0019293020 scopus 로고
    • Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia
    • Kim, J. S.; Kornhuber, H. H.; Schmid-Burgk, W.; Holzmuller, B. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci. Lett. 20:379-382; 1980.
    • (1980) Neurosci. Lett. , vol.20 , pp. 379-382
    • Kim, J.S.1    Kornhuber, H.H.2    Schmid-Burgk, W.3    Holzmuller, B.4
  • 18
    • 0023901123 scopus 로고
    • MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys
    • Koek, W.; Woods, J. H.; Winger, G. D. MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys. J. Pharmacol. Exp. Ther. 245: 969-980; 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.245 , pp. 969-980
    • Koek, W.1    Woods, J.H.2    Winger, G.D.3
  • 19
    • 0028943849 scopus 로고
    • Ketamine activates psychosis and alters limbic blood flow in schizophrenia
    • Lahti, A. C.; Holcomb, H. H.; Medoff, D. R.; Tamminga, C. A. Ketamine activates psychosis and alters limbic blood flow in schizophrenia. Neuroreport 6:869-872; 1995.
    • (1995) Neuroreport , vol.6 , pp. 869-872
    • Lahti, A.C.1    Holcomb, H.H.2    Medoff, D.R.3    Tamminga, C.A.4
  • 20
    • 0025186752 scopus 로고
    • Noncompetitive excitatory amino acid receptor antagonists
    • Lodge, D.; Johnson, K. M. Noncompetitive excitatory amino acid receptor antagonists, Trends Pharmacol. Sci. 11:81-86; 1990.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 81-86
    • Lodge, D.1    Johnson, K.M.2
  • 21
    • 0024784334 scopus 로고
    • Comparative electroencephalographic and behavioral effects of phencyclidine, (+)-SKF-10,047 and MK-801 in rats
    • Marquis, K. L.; Paquette, N. C.; Gussio, R. P.; Moreton, J. E. Comparative electroencephalographic and behavioral effects of phencyclidine, (+)-SKF-10,047 and MK-801 in rats. J. Pharmacol. Exp. Ther. 251:1104-1112; 1989.
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 1104-1112
    • Marquis, K.L.1    Paquette, N.C.2    Gussio, R.P.3    Moreton, J.E.4
  • 22
    • 0028179069 scopus 로고
    • N-methyl-D-aspartic acid receptor structure and function
    • McBain, C. J.; Mayer, M. L. N-methyl-D-aspartic acid receptor structure and function. Physiol. Rev. 74:723-760; 1994.
    • (1994) Physiol. Rev. , vol.74 , pp. 723-760
    • McBain, C.J.1    Mayer, M.L.2
  • 23
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • Meldrum, B. S. The role of glutamate in epilepsy and other CNS disorders. Neurology 44(Suppl. 8):S14-S23; 1994.
    • (1994) Neurology , vol.44 , Issue.SUPPL. 8
    • Meldrum, B.S.1
  • 24
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney, J. W.; Labruyere, J.; Price, M. T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244:1360-1362; 1989.
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 25
    • 0025008963 scopus 로고
    • Intraventricular administration of an N-methyl-D-aspartate receptor antagonist disrupts vestibular compensation
    • Sansom, A. J.; Darlington, C. L.; Smith, P. F. Intraventricular administration of an N-methyl-D-aspartate receptor antagonist disrupts vestibular compensation. Neuropharmacology 29:83-84; 1990.
    • (1990) Neuropharmacology , vol.29 , pp. 83-84
    • Sansom, A.J.1    Darlington, C.L.2    Smith, P.F.3
  • 26
    • 0023739425 scopus 로고
    • The NMDA antagonists MK-801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig
    • Smith, P. F.; Darlington, C. L. The NMDA antagonists MK-801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig. Neurosci. Lett. 94:309-313; 1988.
    • (1988) Neurosci. Lett. , vol.94 , pp. 309-313
    • Smith, P.F.1    Darlington, C.L.2
  • 28
    • 0018638978 scopus 로고
    • Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotyped behavior and ataxia in rats
    • Sturgeon, R. D.; Fessler, R. G.; Meltzer, H. Y. Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotyped behavior and ataxia in rats. Eur. J. Pharmacol. 59: 169-179; 1979.
    • (1979) Eur. J. Pharmacol. , vol.59 , pp. 169-179
    • Sturgeon, R.D.1    Fessler, R.G.2    Meltzer, H.Y.3
  • 29
    • 0024363603 scopus 로고
    • Effects of the NMDA antagonists CPP and MK-801 on delayed conditional discrimination
    • Berlin
    • Tan, S.; Kirk, R. C.; Abraham, W. C.; McNaughton, N. Effects of the NMDA antagonists CPP and MK-801 on delayed conditional discrimination. Psychopharmacology (Berlin) 98:556-560; 1989.
    • (1989) Psychopharmacology , vol.98 , pp. 556-560
    • Tan, S.1    Kirk, R.C.2    Abraham, W.C.3    McNaughton, N.4
  • 30
    • 0023133783 scopus 로고
    • Muscle relaxant and anticonvulsant activity of (3-(±)-2-carboxypiperazin-4-yl)-propyl-1 phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents
    • Turski, L.; Klockgether, T.; Sontag, K. H.; Herrling, P. L.; Watkins, J. C. Muscle relaxant and anticonvulsant activity of (3-(±)-2-carboxypiperazin-4-yl)-propyl-1 phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodents. Neurosci. Lett. 73: 143-148; 1987.
    • (1987) Neurosci. Lett. , vol.73 , pp. 143-148
    • Turski, L.1    Klockgether, T.2    Sontag, K.H.3    Herrling, P.L.4    Watkins, J.C.5
  • 31
    • 0026022884 scopus 로고
    • Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage
    • Uematsu, D.; Araki, N.; Greenberg, J. H.; Sladky, J.; Reivich, M. Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage. Neurology 41:88-94; 1991.
    • (1991) Neurology , vol.41 , pp. 88-94
    • Uematsu, D.1    Araki, N.2    Greenberg, J.H.3    Sladky, J.4    Reivich, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.