Species differences in Cl- affinity and in electrogenicity of SLC26A6-mediated oxalate/Cl- exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis

Journal of Physiology

Volumn 586, Issue 5, 2008, Pages 1291-1306

  Clark, Jeffrey S ^a   Vandorpe, David H ^a   Chernova, Marina N ^a   Heneghan, John F ^a   Stewart, Andrew K ^a   Alper, Seth L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE ION; FORMIC ACID; POLYPEPTIDE; PROTEIN; PROTEIN VARIANT; SLC26A6 PROTEIN; SULFATE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; ORGANIC ANION TRANSPORTER; OXALIC ACID;

AMINO ACID SEQUENCE; ANION TRANSPORT; ARTICLE; DISEASE PREDISPOSITION; HUMAN; JEJUNUM; MOUSE; NEPHROLITHIASIS; NONHUMAN; OOCYTE; OXALATE CHLORIDE EXCHANGE; PRIORITY JOURNAL; PROTEIN DOMAIN; SPECIES DIFFERENCE; XENOPUS; ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CELL TRANSPORT; CHLORIDE TRANSPORT; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOPLASM; ELECTRIC ACTIVITY; GENETIC VARIABILITY; NUCLEOTIDE SEQUENCE; POSTPRANDIAL STATE; RISK FACTOR; TRANSPORT KINETICS;

ANIMALS; ANTIPORTERS; CHLORIDES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYDROGEN-ION CONCENTRATION; HYPEROXALURIA; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT PROTEINS; MICE; NEPHROLITHIASIS; OOCYTES; OXALATES; PATCH-CLAMP TECHNIQUES; SPECIES SPECIFICITY; TRANSFECTION; XENOPUS LAEVIS;

EID: 40049092462     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.143222     Document Type: Article

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