Presence of IgG-CD4 complexes in the circulation

Immunological Investigations

Volumn 37, Issue 2, 2008, Pages 153-162

  Nezlin, Roald ^a   Bengtsson, Anders A ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Dot blot assay; Serum CD4 IgG complexes; Systemic lupus erythematosus

Indexed keywords

CD4 ANTIGEN; IMMUNOGLOBULIN G; MEMBRANE PROTEIN;

ADOLESCENT; ADULT; AGED; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DOT HYBRIDIZATION; HUMAN; IMMUNOBLOTTING; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIGENS, CD4; BLOTTING, WESTERN; HUMANS; IMMUNOGLOBULIN G; LUPUS ERYTHEMATOSUS, SYSTEMIC;

EID: 40049084165     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.1080/08820130701854339     Document Type: Article

References (19)

1. Bandyopadhyay, S., Mukherjee, K., Chatterjee, M. Bhattacharya, D .K., Mandal, C. (2005). Detection of immune-complexed 9-O-acetylated sialoglyconjugates in the sera of patients with pediatric acute lymphobalstic leukemia. J. Immunol. Meth. 297:13-26.
2. 2 mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobilins. Nature Med. 9:431-438.
3. Bengtsson, A., Nezlin, R., Shonfeld, I., Sturfelt, G. (1999). DNA levels in circulating immune complexes decrease at severe SLE flares - correlation with complement component C1q. J. Autoimmun. 13:111-119.
4. Blobel, C. P. (2000). Remarkable roles of proteolysis on and beyond the cell surface. Curr. Opin. Cell Biol. 12: 606-612.
5. Böhm, I. (2000). Quantification of absolute peripheral white blood cells and their subsets in patients with lupus erythematosus: comparison with other inflammatory diseases with and without autoimmune background. Biomed. Pharmacother. 60: 92-95.
6. Brady, R. L., Barclay, A. N. (1996). The structure of CD4. In: Littman D. R., ed. The CD4 molecule. Springer: Berlin. Pp. 1-18.
7. Crispin, J. C., Martinez, A., Alcocer-Varela, J. (2003). Quantification of regulatory T cells in patients with systemic lupus erythematosus. J. Autoimmun. 21:273-276.
8. Gladman, D. D., Ibanez, D., Unowitz, M. B. (2000). Systemic lupus erythematosus disease activity index 2000. J. Rheumatol. 29:288-291.
9. Lenert, P., Kroon, D., Spiegelberg, H., Golub, E. S., Zanetti, M. (1990). Human CD4 binds immunoglobilins. Science 248:1639-1643.
10. Miyara, M., Amoura, Z., Parizot, C., Badoual, C., Dorgham, K., Trad, S., Nochy, D., Debré, P., Piette, J-C., Gorochov, G. (2005). Global natural regulatory T cell depletion in active systemic lupus erythematosus. J. Immunol. 175:8392-8400.
11. Nezlin, R. (1993). Detection of the C3a complement component in commercial gamma globulins by dot blotting. J. Immunol. Meth. 163:269-272.
12. Nezlin, R. (2000). A quantitative approach to the determination of antigen in immune complexes. J. Immunol. Meth. 237:1-17.
13. Nezlin, R., Ghetie, V. (2004). Interactions of immunoglobulins outside the antigen-combining sites. Adv. Immunol. 82:155-215.
14. Nezlin, R., Freywald, A., Oppermann, M. (1993). Complexes of IgG molecules and C3a and C4a complement components in human serum. Mol. Immunol. 30: 35-940.
15. Symons, J. A., McCulloch, J. F., Wood, N. C., Duff, G. W. (1991). Soluble CD4 in patients with rheumatoid arthritis and osteoarthritis. Clin. Immunol. Immunopath. 60:72-82.
16. Tan, E. M., Cohen, A. S., Fries, J. F., Masi, A. T., McShane, D. J., Rothfield, N. F., Schaller, J. G., Talal, N., Winchester, R. J. (1982). The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthr. Rheum. 25:1271-1277.
17. Walker, A. M., Montgomery, D. W., Saraiya, S., Ho, T. W. C., Garewale, H. S., Wilson, J., Lorand, L. (1995). Prolactin-immunoglobulin G complexes from human serum act as costimulatory ligands causing proliferation of malignant B lymphocytes. Proc. Natl. Acad. Sci. USA 92:3278-3282.
18. Yoneyama, A., Nakahara, K., Hiqashihara, M., Kurokawa, K. (1995). Increased levels of soluble CD8 and CD4 in patients with infectious mononucleosis. Brit. J. Haematol. 89:47-54.
19. Zhou, M., Lucas, D. A., Chan, K. C., Issaq, H. J., Petricoin, E. F., Liotta, L. A., Veenstra, T. D., Conrads, T. P. (2004). An investigation into the human serum "interactome." Electrophoresis 25:1289-1298.