Supercritical fluid drying of carbohydrates: Selection of suitable excipients and process conditions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 68, Issue 3, 2008, Pages 781-794

  Bouchard, Andréanne ^a   Jovanović, Nataša ^b   Hofland, Gerard W ^a   Jiskoot, Wim ^c   Mendes, Eduardo ^d   Crommelin, Daan J A ^b   Witkamp, Geert Jan ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

^d DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Amorphous powder; Aqueous solution; Carbohydrates; Crystallisation; Ethanol; Excipients; Supercritical carbon dioxide

Indexed keywords

ALCOHOL; CARBOHYDRATE DERIVATIVE; CARBON DIOXIDE; CYCLODEXTRIN; DEXTRAN; EXCIPIENT; GLUCOSE; INULIN; LACTOSE; LEUCROSE; MALTITOL; MALTOSE; MANNITOL; RAFFINOSE; SOLVENT; SORBITOL; SUCROSE; SUGAR; TREHALOSE; WATER; XYLITOL;

AQUEOUS SOLUTION; ARTICLE; CRYSTALLIZATION; GENERAL AND MISCELLANEOUS PROCEDURES AND TECHNIQUES; GLASS TRANSITION TEMPERATURE; POWDER; ROOM TEMPERATURE; SOLUBILITY; SUPERCRITICAL FLUID; SUPERCRITICAL FLUID DRYING; VISCOSITY;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBOHYDRATES; ETHANOL; EXCIPIENTS; FREEZE DRYING; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; THERMOGRAVIMETRY; X-RAY DIFFRACTION;

EID: 39849109833     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.06.019     Document Type: Article

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