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Volumn 40, Issue 2, 2008, Pages 149-157

Genetically engineered K cells provide sufficient insulin to correct hyperglycemia in a nude murine model

Author keywords

Gene therapy; Glucose; Glucose dependent insulinotropic polypeptide; Insulin; STC 1 cell; Type 1 diabetes mellitus

Indexed keywords

INSULIN; PRIMER DNA; RECOMBINANT PROTEIN;

EID: 39749193212     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2008.00387.x     Document Type: Article
Times cited : (12)

References (27)
  • 2
    • 9644294263 scopus 로고    scopus 로고
    • Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    • Rother KI, Harlan DM. Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest 2004, 114 : 877 883.
    • (2004) J Clin Invest , vol.114 , pp. 877-883
    • Rother, K.I.1    Harlan, D.M.2
  • 4
    • 0037447799 scopus 로고    scopus 로고
    • Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene functions through a GATA and an ISL-1 motif in a mouse neuroendocrine tumor cell line
    • Jepeal LI, Boylan MO, Wolfe MM. Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene functions through a GATA and an ISL-1 motif in a mouse neuroendocrine tumor cell line. Regul Pept 2003, 113 : 139 147.
    • (2003) Regul Pept , vol.113 , pp. 139-147
    • Jepeal, L.I.1    Boylan, M.O.2    Wolfe, M.M.3
  • 6
    • 0025296197 scopus 로고
    • Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression
    • Rindi G, Grant SG, Yiangou Y, Ghatei MA, Bloom SR, Bautch VL, Solcia E et al. Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression. Am J Pathol 1990, 136 : 1349 1363.
    • (1990) Am J Pathol , vol.136 , pp. 1349-1363
    • Rindi, G.1    Grant, S.G.2    Yiangou, Y.3    Ghatei, M.A.4    Bloom, S.R.5    Bautch, V.L.6    Solcia, E.7
  • 7
    • 0036325689 scopus 로고    scopus 로고
    • Novel insulin/GIP co-producing cell lines provide unexpected insights into gut K-cell function in vivo
    • Ramshur EB, Rull TR, Wice BM. Novel insulin/GIP co-producing cell lines provide unexpected insights into gut K-cell function in vivo. J Cell Physiol 2002, 192 : 339 350.
    • (2002) J Cell Physiol , vol.192 , pp. 339-350
    • Ramshur, E.B.1    Rull, T.R.2    Wice, B.M.3
  • 8
    • 0037628628 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells
    • Suzuki A, Nakauchi H, Taniguchi H. Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells. Proc Natl Acad Sci USA 2003, 100 : 5034 5039.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5034-5039
    • Suzuki, A.1    Nakauchi, H.2    Taniguchi, H.3
  • 12
    • 0345269157 scopus 로고    scopus 로고
    • Studies with GIP/Ins cells indicate secretion by gut K cells is KATP channel independent
    • Wang SY, Chi MM, Li L, Moley KH, Wice BM. Studies with GIP/Ins cells indicate secretion by gut K cells is KATP channel independent. Am J Physiol Endocrinol Metab 2003, 284 : E988 E1000.
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Wang, S.Y.1    Chi, M.M.2    Li, L.3    Moley, K.H.4    Wice, B.M.5
  • 13
    • 0030814103 scopus 로고    scopus 로고
    • Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line
    • Boylan MO, Jepeal LI, Jarboe LA, Wolfe MM. Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line. J Biol Chem 1997, 272 : 17438 17443.
    • (1997) J Biol Chem , vol.272 , pp. 17438-17443
    • Boylan, M.O.1    Jepeal, L.I.2    Jarboe, L.A.3    Wolfe, M.M.4
  • 14
    • 11144230786 scopus 로고    scopus 로고
    • Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
    • Jepeal LI, Fujitani Y, Boylan MO, Wilson CN, Wright CV, Wolfe MM. Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1. Endocrinology 2005, 146 : 383 391.
    • (2005) Endocrinology , vol.146 , pp. 383-391
    • Jepeal, L.I.1    Fujitani, Y.2    Boylan, M.O.3    Wilson, C.N.4    Wright, C.V.5    Wolfe, M.M.6
  • 15
    • 12144287255 scopus 로고    scopus 로고
    • Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administration
    • He CX, Shi D, Wu WJ, Ding YF, Feng DM, Lu B, Chen HM et al. Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administration. World J Gastroenterol 2004, 10 : 567 572.
    • (2004) World J Gastroenterol , vol.10 , pp. 567-572
    • He, C.X.1    Shi, D.2    Wu, W.J.3    Ding, Y.F.4    Feng, D.M.5    Lu, B.6    Chen, H.M.7
  • 17
    • 0030948732 scopus 로고    scopus 로고
    • Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression
    • Clark SA, Quaade C, Constandy H, Hansen P, Halban P, Ferber S, Newgard CB et al. Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. Diabetes 1997, 46 : 958 967.
    • (1997) Diabetes , vol.46 , pp. 958-967
    • Clark, S.A.1    Quaade, C.2    Constandy, H.3    Hansen, P.4    Halban, P.5    Ferber, S.6    Newgard, C.B.7
  • 18
    • 0033587485 scopus 로고    scopus 로고
    • Reversal of diabetes in mice by implantation of human fibroblasts genetically engineered to release mature human insulin
    • Falqui L, Martinenghi S, Severini GM, Corbella P, Taqlietti MV, Arcelloni C, Sarugeri E et al. Reversal of diabetes in mice by implantation of human fibroblasts genetically engineered to release mature human insulin. Hum Gene Ther 1999, 10 : 1753 1762.
    • (1999) Hum Gene Ther , vol.10 , pp. 1753-1762
    • Falqui, L.1    Martinenghi, S.2    Severini, G.M.3    Corbella, P.4    Taqlietti, M.V.5    Arcelloni, C.6    Sarugeri, E.7
  • 19
    • 0034628519 scopus 로고    scopus 로고
    • Engineering of a glucose-responsive surrogate cell for insulin replacement therapy of experimental insulin-dependent diabetes
    • Tiedge M, Elsner M, McClenaghan NH, Hedrich HJ, Grube D, Klempnauer J, Lenzen S. Engineering of a glucose-responsive surrogate cell for insulin replacement therapy of experimental insulin-dependent diabetes. Hum Gene Ther 2000, 11 : 403 414.
    • (2000) Hum Gene Ther , vol.11 , pp. 403-414
    • Tiedge, M.1    Elsner, M.2    McClenaghan, N.H.3    Hedrich, H.J.4    Grube, D.5    Klempnauer, J.6    Lenzen, S.7
  • 20
    • 0035038843 scopus 로고    scopus 로고
    • Insulinoma-induced hypoglycemic death in mice is prevented with beta cell-specific gene therapy
    • Tirone TA, Fagan SP, Templeton NS, Wang X, Brunicardi FC. Insulinoma-induced hypoglycemic death in mice is prevented with beta cell-specific gene therapy. Ann Surg 2001, 233 : 603 611.
    • (2001) Ann Surg , vol.233 , pp. 603-611
    • Tirone, T.A.1    Fagan, S.P.2    Templeton, N.S.3    Wang, X.4    Brunicardi, F.C.5
  • 21
    • 0029874328 scopus 로고    scopus 로고
    • Loss of ganciclovir sensitivity by exclusion of thymidine kinase gene from transplanted proinsulin-producing fibroblasts as a gene therapy model for diabetes
    • Yoshimoto K, Murakami R, Moritani M, Ohta M, Iwahana H, Nakauchi H, Itakura M. Loss of ganciclovir sensitivity by exclusion of thymidine kinase gene from transplanted proinsulin-producing fibroblasts as a gene therapy model for diabetes. Gene Ther 1996, 3 : 230 234.
    • (1996) Gene Ther , vol.3 , pp. 230-234
    • Yoshimoto, K.1    Murakami, R.2    Moritani, M.3    Ohta, M.4    Iwahana, H.5    Nakauchi, H.6    Itakura, M.7
  • 22
    • 0031171411 scopus 로고    scopus 로고
    • Constant delivery of proinsulin by encapsulation of transfected cells
    • Taniguchi H, Fukao K, Nakauchi H. Constant delivery of proinsulin by encapsulation of transfected cells. J Surg Res 1997, 70 : 41 45.
    • (1997) J Surg Res , vol.70 , pp. 41-45
    • Taniguchi, H.1    Fukao, K.2    Nakauchi, H.3
  • 24
    • 0031593872 scopus 로고    scopus 로고
    • In vitro and in vivo assessment of adenovirus 41 as a vector for gene delivery to the intestine
    • Croyle MA, Stone M, Amidon GL, Roessler BJ. In vitro and in vivo assessment of adenovirus 41 as a vector for gene delivery to the intestine. Gene Ther 1998, 5 : 645 654.
    • (1998) Gene Ther , vol.5 , pp. 645-654
    • Croyle, M.A.1    Stone, M.2    Amidon, G.L.3    Roessler, B.J.4
  • 25
    • 0031721136 scopus 로고    scopus 로고
    • Peroral gene therapy of lactose intolerance using an adeno-associated virus vector
    • During MJ, Xu R, Young D, Kaplitt MG, Sherwin RS, Leone P. Peroral gene therapy of lactose intolerance using an adeno-associated virus vector. Nat Med 1998, 4 : 1131 1135.
    • (1998) Nat Med , vol.4 , pp. 1131-1135
    • During, M.J.1    Xu, R.2    Young, D.3    Kaplitt, M.G.4    Sherwin, R.S.5    Leone, P.6
  • 26
    • 0141455064 scopus 로고    scopus 로고
    • PEGylated adenoviruses for gene delivery to the intestinal epithelium by the oral route
    • Cheng X, Ming X, Croyle MA. PEGylated adenoviruses for gene delivery to the intestinal epithelium by the oral route. Pharm Res 2003, 20 : 1444 1451.
    • (2003) Pharm Res , vol.20 , pp. 1444-1451
    • Cheng, X.1    Ming, X.2    Croyle, M.A.3
  • 27
    • 33644843061 scopus 로고    scopus 로고
    • Regulated production of mature insulin in rat hepatoma cells: Insulin production is up-regulated by dexamethasone and down-regulated by insulin
    • Qin XY, Shen KT, Song LJ, Zhang X, Han ZG. Regulated production of mature insulin in rat hepatoma cells: insulin production is up-regulated by dexamethasone and down-regulated by insulin. Acta Biochim Biophys Sin 2006, 38 : 89 94.
    • (2006) Acta Biochim Biophys Sin , vol.38 , pp. 89-94
    • Qin, X.Y.1    Shen, K.T.2    Song, L.J.3    Zhang, X.4    Han, Z.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.