The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs

Journal of Biomedical Science

Volumn 15, Issue 2, 2008, Pages 227-238

  Chen, Hsing I ^a   Yeh, Diana Yuwung ^b,c   Kao, Shang Jyh ^b,d  

^a TZU CHI UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Alveolar hemorrhage; Autonomic functions; Inducible nitric oxide; Proinflammatory cytokines; Pulmonary microvascular permeability

Indexed keywords

CALCITONIN; CYTOKINE; MESSENGER RNA; METHYLGUANIDINE; NITRATE; NITRIC OXIDE SYNTHASE; PROCALCITONIN; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; EPITHELIUM CELL; HISTOPATHOLOGY; HYPERCALCEMIA; IMMUNOCHEMISTRY; ISOLATED LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG EDEMA; LUNG LAVAGE; LUNG WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

RATTUS;

EID: 39749174978     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-007-9211-1     Document Type: Article

References (42)

1. 1. L.B. Ware M.A Matthay 2000 The acute respiratory distress syndrome N. Engl. J. Med. 342 1334 1349 10793167 10.1056/NEJM200005043421806 1:STN:280:DC%2BD3c3jvFGhsw%3D%3D Ware L.B., Matthay M.A. (2000) The acute respiratory distress syndrome. N. Engl. J. Med. 342: 1334–1349
2. 2. H.I. Chen S.J. Kao D. Wang R.P. Lee C.F. Su 2003 Acute respiratory distress syndrome J. Biomed. Sci. 10 588 592 14576460 10.1007/BF02256308 Chen H.I., Kao S.J., Wang D., Lee R.P., Su C.F. (2003) Acute respiratory distress syndrome. J. Biomed. Sci. 10: 588–592
3. 3. H.I. Chen S.C. Sun C.Y. Chai 2003 Pulmonary edema and hemorrhage resulting from cerebral compression Am. J. Physiol. 224 223 229 Chen H.I., Sun S.C., Chai C.Y. (2003) Pulmonary edema and hemorrhage resulting from cerebral compression. Am. J. Physiol. 224: 223–229
4. 4. H.I. Chen J.F. Liao L. Kuo S.T Ho 1980 Centrogenic pulmonary hemorrhagic edema induced by cerebral compression in rats Circ. Res. 47 366 373 7408118 1:STN:280:DyaL3M%2Fgt1antA%3D%3D Chen H.I., Liao J.F., Kuo L., Ho S.T. (1980) Centrogenic pulmonary hemorrhagic edema induced by cerebral compression in rats. Mechanism of volume and pressure loading in the pulmonary circulation. Circ. Res. 47: 366–373
5. 5. F. Holmes J. Harlan S. Felt J. Ruhlen B Murphy 1974 Pulmonary oedema in hypercalcaemic crisis Lancet 1 311 312 4130490 10.1016/S0140-6736(74)92615-4 1:STN:280:DyaE2c7gtVKltw%3D%3D Holmes F., Harlan J., Felt S., Ruhlen J., Murphy B. (1974) Pulmonary oedema in hypercalcaemic crisis. Lancet 1: 311–312
6. 6. D.F Bohr 1963 Vascular smooth muscle: dual effects of calcium Science 139 597 599 17788298 10.1126/science.139.3555.597 Bohr D.F. (1963) Vascular smooth muscle: dual effects of calcium. Science 139: 597–599
7. 7. D.E Clapham 1995 Intracellular calcium. Replenishing the stores Nature 375 634 635 7791893 10.1038/375634a0 1:CAS:528:DyaK2MXmsFKrsb8%3D Clapham D.E. (1995) Intracellular calcium. Replenishing the stores. Nature 375: 634–635
8. 8. S. Orrenius B. Zhivotovsky P Nicotera 2003 Regulation of cell death: the calcium-apoptosis link Nat. Rev. Mol. Cell. Biol. 4 552 565 12838338 10.1038/nrm1150 1:CAS:528:DC%2BD3sXltVWnu7g%3D Orrenius S., Zhivotovsky B., Nicotera P. (2003) Regulation of cell death: the calcium-apoptosis link. Nat. Rev. Mol. Cell. Biol. 4: 552–565
9. 9. R.P. Lee D. Wang N.T. Lin Y.W. Chou H.I Chen 2002 A modified technique for tail cuff pressure measurement in unrestrained conscious rats J. Biomed. Sci. 9 424 427 12218357 10.1007/BF02256536 Lee R.P., Wang D., Lin N.T., Chou Y.W., Chen H.I. (2002) A modified technique for tail cuff pressure measurement in unrestrained conscious rats. J. Biomed. Sci. 9: 424–427
10. 10. R.P. Lee D. Wang S.J. Kao H.I. Chen 2001 The lung is the major site that produces nitric oxide to induce acute pulmonary oedema in endotoxin shock Clin. Exp. Pharmacol. Physiol. 28 315 320 11251647 10.1046/j.1440-1681.2001.03446.x 1:CAS:528:DC%2BD3MXjt1Oitrk%3D Lee R.P., Wang D., Kao S.J., Chen H.I. (2001) The lung is the major site that produces nitric oxide to induce acute pulmonary oedema in endotoxin shock. Clin. Exp. Pharmacol. Physiol. 28: 315–320
11. 11. S.J. Kao D. Wang D.Y. Yeh K. Hsu Y.H. Hsu H.I Chen 2004 Static inflation attenuates ischemia/reperfusion injury in an isolated rat lung in situ Chest 126 552 558 15302744 10.1378/chest.126.2.552 Kao S.J., Wang D., Yeh D.Y., Hsu K., Hsu Y.H., Chen H.I. (2004) Static inflation attenuates ischemia/reperfusion injury in an isolated rat lung in situ. Chest 126: 552–558
12. 12. C.C. Yang T.C. Chao T.B. Kuo C.S. Yin H.I Chen 2000 Preeclampic pregnancy is associated with increased sympathetic and decreased parasympathetic control of HR Am. J. Physiol. 278 1269 1273 Yang C.C., Chao T.C., Kuo T.B., Yin C.S., Chen H.I. (2000) Preeclampic pregnancy is associated with increased sympathetic and decreased parasympathetic control of HR. Am. J. Physiol. 278: 1269–1273
13. 13. C.F. Su T.B Kuo J.S. Kuo H.Y. Lai H.I Chen 2005 Sympathetic and parasympathetic activities evaluated by heart-rate variability in head injury of various severities Clin. Neurophysiol. 116 1273 1279 15978489 10.1016/j.clinph.2005.01.010 Su C.F., Kuo T.B, Kuo J.S., Lai H.Y., Chen H.I. (2005) Sympathetic and parasympathetic activities evaluated by heart-rate variability in head injury of various severities. Clin. Neurophysiol. 116: 1273–1279
14. 14. H.I. Chen D.Y. Yeh H.L. Liou S.J Kao 2006 Insulin attenuates endotoxin-induced acute lung injury in conscious rats Crit. Care Med. 34 758 764 16505662 10.1097/01.CCM.0000201902.37115.22 1:CAS:528:DC%2BD28Xhs12gu7w%3D Chen H.I., Yeh D.Y., Liou H.L., Kao S.J. (2006) Insulin attenuates endotoxin-induced acute lung injury in conscious rats. Crit. Care Med. 34: 758–764
15. 15. S.J. Kao D. Wang H.I. Lin H.I Chen 2006 N-Acetylcysteine abrogates acute lung injury induced by endotoxin Clin. Exp. Pharmacol. Physiol. 33 33 40 16445696 10.1111/j.1440-1681.2006.04320.x 1:CAS:528:DC%2BD28XitlGntrk%3D Kao S.J., Wang D., Lin H.I., Chen H.I. (2006) N-Acetylcysteine abrogates acute lung injury induced by endotoxin. Clin. Exp. Pharmacol. Physiol. 33: 33–40
16. 16. G. Thurston J.S. Rudge E. Ioffe H. Zhou L. Ross S.D. Croll N. Glazer J. Holash D.M. McDonald G.D Yancopoulos 2000 Angiopoietin-1 protects the adult vasculature against plasma leakage Nat. Med. 6 460 463 10742156 10.1038/74725 1:CAS:528:DC%2BD3cXisVygsbc%3D Thurston G., Rudge J.S., Ioffe E., Zhou H., Ross L., Croll S.D., Glazer N., Holash J., McDonald D.M., Yancopoulos G.D. (2000) Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat. Med. 6: 460–463
17. 17. M.N. Muscara G Nucci 1996 Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions J. Chromatogr. B Biomed. Appl. 686 157 164 8971596 10.1016/S0378-4347(96)00229-0 1:CAS:528:DyaK2sXkvVGm Muscara M.N., Nucci G. (1996) Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions. J. Chromatogr. B Biomed. Appl. 686: 157–164
18. 18. R.P. Lee D. Wang N.T. Lin H.I Chen 2002 Physiological and chemical indicators for early and late stages of sepsis in conscious rats J. Biomed. Sci. 9 613 621 12432227 10.1007/BF02254989 1:CAS:528:DC%2BD3sXptVOjsA%3D%3D Lee R.P., Wang D., Lin N.T., Chen H.I. (2002) Physiological and chemical indicators for early and late stages of sepsis in conscious rats. J. Biomed. Sci. 9: 613–621
19. 19. K. Nakamura K Ienaga T. Yokozawa N. Fujitsuka H Oura 1991 Production of methylguanidine from creatinine via creatol by active oxygen species: analyses of the catabolism in vitro Nephron 58 42 46 1649975 1:CAS:528:DyaK3MXit1OjsLo%3D 10.1159/000186376 Nakamura K., Ienaga K, Yokozawa T., Fujitsuka N., Oura H. (1991) Production of methylguanidine from creatinine via creatol by active oxygen species: analyses of the catabolism in vitro. Nephron 58: 42–46
20. 20. Q. Jiang L. DeTolla N. Rooijen van I.S. Singh B. Fitzgerald M.M. Lipsky A.S. Kane A.S. Cross J.D Hasday 1999 Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin Infect. Immun. 67 1539 1546 10084984 1:CAS:528:DyaK1MXitFCkurc%3D Jiang Q., DeTolla L., van Rooijen N., Singh I.S., Fitzgerald B., Lipsky M.M., Kane A.S., Cross A.S., Hasday J.D. (1999) Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin. Infect. Immun. 67: 1539–1546
21. 21. H. Ugarte E. Silva D. Mercan A. Mendonca De J.L Vincent 1999 Procalcitonin used as a marker of infection in the intensive care unit Crit. Care Med. 27 498 504 10199528 10.1097/00003246-199903000-00024 1:STN:280:DyaK1M3htlKhsg%3D%3D Ugarte H., Silva E., Mercan D., De Mendonca A., Vincent J.L. (1999) Procalcitonin used as a marker of infection in the intensive care unit. Crit. Care Med. 27: 498–504
22. 22. G.A. Wanner M. Keel U. Steckholzer W. Beier R. Stocker W Ertel 2000 Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients Crit. Care Med. 28 950 957 10809265 10.1097/00003246-200004000-00007 1:STN:280:DC%2BD3c3mslalsA%3D%3D Wanner G.A., Keel M., Steckholzer U., Beier W., Stocker R., Ertel W. (2000) Relationship between procalcitonin plasma levels and severity of injury, sepsis, organ failure, and mortality in injured patients. Crit. Care Med. 28: 950–957
23. 23. C. Balci H. Sungurtekin E. Gurses U. Sungurtekin B Kaptanoglu 2002 Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit Crit. Care 7 85 90 12617745 10.1186/cc1843 Balci C., Sungurtekin H., Gurses E., Sungurtekin U., Kaptanoglu B. (2002) Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit. Crit. Care 7: 85–90
24. 24. S.R. Shi M.E. Key K.L Kalra 1991 Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections J. Histochem. Cytochem. 39 741 748 1709656 1:CAS:528:DyaK3MXkt1Gns7c%3D Shi S.R., Key M.E., Kalra K.L. (1991) Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J. Histochem. Cytochem. 39: 741–748
25. 25. N.T. Lin F.L. Yang R.P. Lee T.C. Peng H.I Chen 2006 Inducible nitric oxide synthase mediates cytokine release: the time course in conscious septic rats Life Sci. 78 1038 1043 16181643 10.1016/j.lfs.2005.05.091 1:CAS:528:DC%2BD28XotVOhtA%3D%3D Lin N.T., Yang F.L., Lee R.P., Peng T.C., Chen H.I. (2006) Inducible nitric oxide synthase mediates cytokine release: the time course in conscious septic rats. Life Sci. 78: 1038–1043
26. 26. U.B. Chaudhary D.L. Milling N.K Bissada 2004 Transitional cell carcinoma of the bladder producing parathyroid hormone-related protein (PTHrP) Can. J. Urol. 11 2136 2138 15003153 Chaudhary U.B., Milling D.L., Bissada N.K. (2004) Transitional cell carcinoma of the bladder producing parathyroid hormone-related protein (PTHrP). Can. J. Urol. 11: 2136–2138
27. 27. P Esbrit 2001 Hypercalcemia of malignancy—new insights into an old syndrome Clin. Lab. 47 67 71 11214225 1:CAS:528:DC%2BD3MXhtF2htbc%3D Esbrit P. (2001) Hypercalcemia of malignancy—new insights into an old syndrome. Clin. Lab. 47: 67–71
28. 28. R.C. Bone C.J. Grodzin R.A Balk 1997 Sepsis, a new hypothesis for pathogenesis of the disease process Chest 112 235 243 9228382 10.1378/chest.112.1.235 1:STN:280:DyaK2sznt1Wiug%3D%3D Bone R.C., Grodzin C.J., Balk R.A. (1997) Sepsis, a new hypothesis for pathogenesis of the disease process. Chest 112: 235–243
29. 29. A.P. Wheeler G.R Bernard 1999 Treating patients with severe sepsis N. Engl. J. Med. 340 207 214 9895401 10.1056/NEJM199901213400307 1:STN:280:DyaK1M7gtFylug%3D%3D Wheeler A.P., Bernard G.R. (1999) Treating patients with severe sepsis. N. Engl. J. Med. 340: 207–214
30. 30. G. Camussi C. Ronco G. Montrucchio G Piccoli 1998 Role of soluble mediators in sepsis and renal failure Kidney Int. 66 S38 S42 1:CAS:528:DyaK1cXjtV2iur4%3D Camussi G., Ronco C., Montrucchio G., Piccoli G. (1998) Role of soluble mediators in sepsis and renal failure. Kidney Int. 66: S38–S42
31. 31. K.L. Huang K.P. Shaw D. Wang K. Hsu T.S. Huang H.I Chen 2002 Free radicals mediate amphetamine-induced acute pulmonary edema in isolated rat lung Life Sci. 71 1237 1244 12106589 10.1016/S0024-3205(02)01847-7 1:CAS:528:DC%2BD38XltFWjt7o%3D Huang K.L., Shaw K.P., Wang D., Hsu K., Huang T.S., Chen H.I. (2002) Free radicals mediate amphetamine-induced acute pulmonary edema in isolated rat lung. Life Sci. 71: 1237–1244
32. 32. B.G. Hsu F.L. Yang R.P. Lee T.C. Peng H.I Chen 2005 Effects of post-treatment with low-dose propofol on inflammatory responses to lipopolysaccharide-induced shock in conscious rats Clin. Exp. Pharmacol. Physiol. 32 24 29 15730430 10.1111/j.1440-1681.2005.04155.x Hsu B.G., Yang F.L., Lee R.P., Peng T.C., Chen H.I. (2005) Effects of post-treatment with low-dose propofol on inflammatory responses to lipopolysaccharide-induced shock in conscious rats. Clin. Exp. Pharmacol. Physiol. 32: 24–29
33. 33. C.C. Lee N.T. Lin Y.H. Hsu H.I Chen 2005 Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats J. Cardiovasc. Pharmacol. 45 396 403 15821434 10.1097/01.fjc.0000157438.72483.ae 1:CAS:528:DC%2BD2MXjtVOju7k%3D Lee C.C., Lin N.T., Hsu Y.H., Chen H.I. (2005) Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats. J. Cardiovasc. Pharmacol. 45: 396–403
34. 34. P. Agouridakis D. Kyriakou M.G. Alexandrakis A. Prekates K. Perisinakis N. Karkavitsas D Bouros 2002 The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome Respir. Res. 3 25 33 12537603 10.1186/rr193 Agouridakis P., Kyriakou D., Alexandrakis M.G., Prekates A., Perisinakis K., Karkavitsas N., Bouros D. (2002) The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome. Respir. Res. 3: 25–33
35. 35. A.K. Hesse M. Dörger C. Kupatt F Krombach 2004 Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury Respir. Res. 5 11 20 15377396 10.1186/1465-9921-5-11 1:CAS:528:DC%2BD2cXoslSrsbs%3D Hesse A.K., Dörger M., Kupatt C., Krombach F. (2004) Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury. Respir. Res. 5: 11–20
36. 36. W.M. Zapol S. Rimar N. Gillis M. Marletta C.H. Bosken 1994 Nitric oxide and the lung Am. J. Respir. Crit. Care Med. 149 1375 1380 8173780 1:STN:280:DyaK2c3ivVSrtg%3D%3D Zapol W.M., Rimar S., Gillis N., Marletta M., Bosken C.H. (1994) Nitric oxide and the lung. Am. J. Respir. Crit. Care Med. 149: 1375–1380
37. 37. D. Wang J. Wei K. Hsu J. Jau M.W. Lieu T.J. Chao H.I Chen 1999 Effects of nitric oxide synthase inhibitors on systemic hypotension, cytokines and inducible nitric oxide synthase expression and lung injury following endotoxin administration in rats J. Biomed. Sci. 6 28 35 9933740 10.1007/BF02256421 Wang D., Wei J., Hsu K., Jau J., Lieu M.W., Chao T.J., Chen H.I. (1999) Effects of nitric oxide synthase inhibitors on systemic hypotension, cytokines and inducible nitric oxide synthase expression and lung injury following endotoxin administration in rats. J. Biomed. Sci. 6: 28–35
38. 38. O.V. Evgenov O. Hevroy K.E. Bremnes L.J Bjertnaes 2000 Effect of aminoguanidine on lung fluid filtration after endotoxin in awake sheep Am. J. Respir. Crit. Care Med. 162 465 470 10934072 1:STN:280:DC%2BD3cvjtlCitg%3D%3D Evgenov O.V., Hevroy O., Bremnes K.E., Bjertnaes L.J. (2000) Effect of aminoguanidine on lung fluid filtration after endotoxin in awake sheep. Am. J. Respir. Crit. Care Med. 162: 465–470
39. 39. S. Cuzzocrea E. Mazzon G. Calabro L. Dugo A. Sarro De F.A. Loo van De A.P Caputi 2000 Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan Am. J. Respir. Crit. Care Med. 162 1859 1866 11069827 1:STN:280:DC%2BD3M%2FkvF2itA%3D%3D Cuzzocrea S., Mazzon E., Calabro G., Dugo L., De Sarro A., van De Loo F.A., Caputi A.P. (2000) Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan. Am. J. Respir. Crit. Care Med. 162: 1859–1866
40. 40. S.J. Kao T.C. Peng R.P. Lee K. Hsu C.F. Chen Y.K. Hung D. Wang H.I Chen 2003 Nitric oxide mediates lung injury induced by ischemia-reperfusion in rats J. Biomed. Sci. 10 58 64 12566987 10.1007/BF02255998 1:CAS:528:DC%2BD3sXjsF2lsw%3D%3D Kao S.J., Peng T.C., Lee R.P., Hsu K., Chen C.F., Hung Y.K., Wang D., Chen H.I. (2003) Nitric oxide mediates lung injury induced by ischemia-reperfusion in rats. J. Biomed. Sci. 10: 58–64
41. 41. C. Tiruppathi G.U. Ahmmed S.M. Vogel A.B Malik 2006 Ca2+ signaling, TRP channels, and endothelial permeability Microcirculation 13 693 708 17085428 10.1080/10739680600930347 1:CAS:528:DC%2BD2sXhvVynsg%3D%3D Tiruppathi C., Ahmmed G.U., Vogel S.M., Malik A.B. (2006) Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation 13: 693–708
42. 42. S.J. F.L. Kao Yang Y.H. Hsu H.I. Chen 2004 Mechanism of fulminant pulmonary edema caused by enterovirus 71 Clin. Infect. Dis. 38 1784 1788 10.1086/380644 Kao S.J. Yang F.L., Hsu Y.H., Chen H.I. (2004) Mechanism of fulminant pulmonary edema caused by enterovirus 71. Clin. Infect. Dis. 38: 1784–1788