Increased granzyme B production from peripheral blood mononuclear cells in patients with acute coronary syndrome

Heart

Volumn 94, Issue 3, 2008, Pages 305-310

  Tsuru, R ^a   Kondo, H ^a   Hojo, Yukihiro ^a   Gama, M ^a   Mizuno, O ^a   Katsuki, T ^a   Shimada, K ^a   Kikuchi, M ^a   Yashiro, T ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CD3 ANTIGEN; GRANZYME B;

ACUTE CORONARY SYNDROME; ADULT; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL ISOLATION; CENTRIFUGATION; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; FEMALE; FLOW CYTOMETRY; HUMAN; INCUBATION TIME; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STABLE ANGINA PECTORIS; STATISTICAL SIGNIFICANCE; SUPERNATANT; UNSTABLE ANGINA PECTORIS;

ACUTE CORONARY SYNDROME; ADULT; AGED; AGED, 80 AND OVER; ANGINA PECTORIS; ANGINA, UNSTABLE; APOPTOSIS; CORONARY DISEASE; FEMALE; FLOW CYTOMETRY; GRANZYMES; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT;

EID: 39749118627     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.2006.110023     Document Type: Article

References (33)

1. Richardson PD, Davies MJ, Born GVR. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet 1989;2:941-4.
2. Cheng GC, Loree HM, Kamm RD, et al. Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. Circulation 1993;87:1179-87.
3. Davies MJ, Richardson PD, Woolf N, et al. Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content. Br Heart J 1993;69:377-81.
4. Moreno PR, Falk E, Palacios IF, et al. Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation 1994;90:775-8.
5. Lendon CL, Davies M, Born GVR, et al. Atherosclerotic plaque caps are locally weakened when macrophages density is increased. Atherosclerosis 1991;87:87-90.
6. Van der Wal AC, Becker AE, van der Loos CM, et al. Site of rupture or erosion of thrombosed coronary atherosclerotic plaque is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994;89:36-44.
7. Kaartinen M, Pettila A, Kovanen PT. Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture. Circulation 1994;90:1669-78.
8. Lee RT, Schoen F, Loree HM, et al. Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture. Arterioscler Thromb Vasc Biol 1996;16:1070-3.
9. Gallis ZS, Sukhova GK, Lark MW, et al. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaque. J Clin Invest 1994;94:2493-2503.
10. Baldus S, Heeschen C, Meinertz T, et al. CAPTURE Investigators. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation 2003;108:1440-5.
11. Naruko T, Ueda M, Haze K, et al. Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation 2002;106:2894-2900.
12. Sugiyama S, Okada Y, Sukhova GK, et al. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol 2001;158:879-91.
13. Elneihoum AM, Falke P, Hedblad B, et al. Leukocyte activation in atherosclerosis: correlation with risk factors. Atherosclerosis 1997;131:79-84.
14. Darmon AJ, Nicholson DW, Bleackley RC. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 1995;377:446-8.
15. Heibein JA, Goping IS, Barry M, et al. Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax. J Exp Med 2000;192:1391-402.
16. Barry M, Heibein JA, Pinkoski MJ, et al. Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid. Mol Cell Biol 2000;20:3781-94.
17. Edwards KM, Kam CM, Powers JC, et al. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes. J Biol Chem 1999;274:30468-73.
18. Froelich CJ, Zhang X, Turbov J, et al. Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes. J Immunol 1993;151:7161-71.
19. Buzza MS, Zamurs L, Sun J, et al. Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin. J Biol Chem 2005;280:23549-58.
20. World Medical Association Declaration of Helsinki. Recommendations guiding physicians in biomedical research involving human subjects. Cardiovasc Res 1997;35:2-3.
21. Cannon CP, Braunwald E. Unstable Angina. In: Braunwald E, Zeipes DP, Libby P, eds. Heart Disease. Philadelphia, Pennsylvania: W.B. Saunders Company, 2001:1232-71.
22. Ninomiya JK, L'Italien G, Criqui MH, et al. Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation 2004;109:42-6.
23. Ledue TB, Weiner DL, Sipe JD, et al. Analytical evaluation of particle-enhanced immunonephelometric assays for C-reactive protein, serum amyloid A and mannose-binding protein in human serum. Ann Clin Biochem 1998;35:745-53.
24. Antman EM, Cohen M, Bernink PJ, et al. The TIMI risk score for unstable angina/ non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA 2000;284:835-42.
25. Nakajima T, Schulte S, Warrington KJ, et al. T-cell-mediated lysis of endothelial cells in acute coronary syndromes. Circulation 2002;105:570-5.
26. Choy JC, Hung VH, Hunter AL, et al. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arterioscler Thromb Vasc Biol 2004;24:2245-50.
27. Lindstedt KA, Kovanen PT. Proteolysis of pericellular matrix: a process linking inflammation to plaque destabilization and rupture. Arterioscler Thromb Vasc Biol 2004;24:2205-6.
28. Buzza MS, Zamurs L, Sun J, et al. Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin. J Biol Chem 2005;280:23549-58.
29. Momiyama Y, Ohmori R, Taniguchi H, et al. Association of Mycoplasma pneumoniae infection with coronary artery disease and its interaction with chlamydial infection. Atherosclerosis 2004;176:139-44.
30. Rupprecht HJ, Blankenberg S, Bickel C, et al. AutoGene Investigators. Impact of viral and bacterial infectious burden on long-term prognosis in patients with coronary artery disease. Circulation 2001;104:25-31.
31. Sun Y, Pei W, Welte T, et al. Cytomegalovirus infection is associated with elevated interleukin-10 in coronary artery disease. Atherosclerosis 2005;179:133-7.
32. Folsom AR, Nieto FJ, Sorlie P, et al. Atherosclerosis Risk In Communities (ARIC) Study Investigators. Helicobacter pylori seropositivity and coronary heart disease incidence. Circulation 1998;98:845-50.
33. Yap SH, Morshage HJ, Hanzenberg BP, et al. Tumor necrosis factor (TNF) inhibits interleukin (IL)-1 and/or IL-6 stimulated synthesis of C-reactive protein (CRP) and serum amyloid A (SAA) in primary cultures of human hepatocytes. Biochim Biophys Acta 1991;1091:405-8.