Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation

Biochemical Pharmacology

Volumn 75, Issue 6, 2008, Pages 1341-1347

  Gao, Zhan Guo ^a   Hechler, Béatrice ^b,c,d   Besada, Pedro ^a   Gachet, Christian ^b,c,d   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b INSERM   (France)

^c ETABLISSEMENT FRANÇAIS DU SANG   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Aggregation; Calcium; G protein coupled receptors; Nucleotides; Phospholipase C

Indexed keywords

2 (METHYLTHIO)ADENOSYL 1 (4,5 DIMETHOXY 2 NITROPHENYL)ETHYLPYROPHOSPHATE; CALCIUM; MRS 2703; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG; 2 METHYLTHIOADENOSINE DIPHOSPHATE; 2-METHYLTHIO-ADP; ADENOSINE DIPHOSPHATE; DRUG DERIVATIVE; NUCLEOTIDE; P1 2 (METHYLTHIO)ADENOSYL P2 1 (4,5 DIMETHOXY 2 NITROPHENYL)ETHYL PYROPHOSPHATE; P1-2-(METHYLTHIO)ADENOSYL-P2-1-(4,5-DIMETHOXY-2-NITROPHENYL)ETHYL PYROPHOSPHATE; P2RY12 PROTEIN, HUMAN; PURINERGIC P2 RECEPTOR;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IRRADIATION; LIGHT; PHOTOSTIMULATION; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; ULTRAVIOLET RADIATION; CELL CULTURE; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; RADIATION EXPOSURE; SYNTHESIS; TUMOR CELL LINE;

ADENOSINE DIPHOSPHATE; CALCIUM; CELL LINE, TUMOR; CELLS, CULTURED; HUMANS; PLATELET AGGREGATION; RECEPTORS, PURINERGIC P2; THIONUCLEOTIDES; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 39749101264     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.10.037     Document Type: Article

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