The expression of HSP27 is associated with poor clinical outcome in intrahepatic cholangiocarcinoma

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Romani, Antonello A ^a   Crafa, Pellegrino ^a   Desenzani, Silvia ^a   Graiani, Gallia ^a   Lagrasta, Costanza ^a   Sianesi, Mario ^a   Soliani, Paolo ^a   Borghetti, Angelo F ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 27; HISTONE H3; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 72; HSPB1 PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; BILE DUCT CARCINOMA; BILIARY TRACT SURGERY; CANCER GROWTH; CANCER INVASION; CANCER SURVIVAL; CARCINOGENESIS; CELL PROLIFERATION; CLINICAL ARTICLE; FEMALE; FISHER EXACT TEST; HAZARD RATIO; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LOG RANK TEST; LYMPHOCYTIC INFILTRATION; MALE; MITOSIS INDEX; NULL HYPOTHESIS; OVERALL SURVIVAL; PROGNOSIS; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR NECROSIS; BILE DUCT TUMOR; ENZYME IMMUNOASSAY; INTRAHEPATIC BILE DUCT; METABOLISM; MIDDLE AGED; MITOSIS; NECROSIS; PATHOLOGY; RETROSPECTIVE STUDY; TUMOR ASSOCIATED LEUKOCYTE;

AGED; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CELL PROLIFERATION; CHOLANGIOCARCINOMA; FEMALE; HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; MITOSIS; NECROSIS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 39649117547     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-232     Document Type: Article

References (51)

1. Malhi H Gores GJ Cholangiocarcinoma: Modern advances in understanding a deadly old disease J Hepatol 2006, 45(6):856-867 1686172 17030071 10.1016/j.jhep.2006.09.001
2. Okuda K Nakanuma Y Miyazaki M Cholangiocarcinoma: Recent progress. Part 1: Epidemiology and etiology J Gastroenterol Hepatol 2002, 17(10):1049-1055 10.1046/j.1440-1746.2002.02781.x 12201863
3. Patel T Cholangiocarcinoma Nat Clin Pract Gastroenterol Hepatol 2006, 3(1):33-42 10.1038/ncpgasthep0389 16397610
4. Georgopoulos C Welch WJ Role of the major heat shock proteins as molecular chaperones Annu Rev Cell Biol 1993, 9:601-634 10.1146/ annurev.cb.09.110193.003125 8280473
5. Guenal I Sidoti-de Fraisse C Gaumer S Mignotte B Bcl-2 and Hsp27 act at different levels to suppress programmed cell death Oncogene 1997, 15(3):347-360 10.1038/sj.onc.1201182 9233769
6. Garrido C Brunet M Didelot C Zermati Y Schmitt E Kroemer G Heat shock proteins 27 and 70: Anti-apoptotic proteins with tumorigenic properties Cell Cycle 2006, 5(22):2592-2601 17106261
7. Didelot C Schmitt E Brunet M Maingret L Parcellier A Garrido C Heat shock proteins: Endogenous modulators of apoptotic cell death Handb Exp Pharmacol 2006, 172:171-198 16610360
8. Manjili MH Wang XY Park J Facciponte JG Repasky EA Subjeck JR Immunotherapy of cancer using heat shock proteins Front Biosci 2002, 7:d43-52 10.2741/manjili 11779704
9. Richards EH Hickey E Weber L Master JR Effect of overexpression of the small heat shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells Cancer Res 1996, 56(10):2446-2451 8625326
10. Mosser DD Morimoto RI Molecular chaperones and the stress of oncogenesis Oncogene 2004, 23(16):2907-2918 10.1038/sj.onc.1207529 15077153
11. Shaib YH El-Serag HB Davila JA Morgan R McGlynn KA Risk factors of intrahepatic cholangiocarcinoma in the United States: A case-control study Gastroenterology 2005, 128(3):620-626 10.1053/j.gastro.2004.12.048 15765398
12. Liver (Including Intrahepatic Bile Ducts), Extrahepatic Bile Ducts Joint Committee on Cancer: AJCC Cancer Staging Manual New York: Springer-Verlag Sixth 2002, 131(138):145-150
13. Romani AA Soliani P Desenzani S Borghetti AF Crafa P The associated expression of Maspin and Bax proteins as a potential prognostic factor in intrahepatic cholangiocarcinoma BMC Cancer 2006, 6:255 1635990 17067385 10.1186/1471-2407-6-255
14. Colman H Giannini C Huang L Gonzalez J Hess K Bruner J Fuller G Langford L Pelloski C Aaron J Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas Am J Surg Pathol 2006, 30(5):657-664 10.1097/01.pas.0000202048.28203.25 16699322
15. Kaarniranta K Elo MA Sironen RK Karjalainen HM Helminen HJ Lammi MJ Stress responses of mammalian cells to high hydrostatic pressure Biorheology 2003, 40(1-3):87-92 12454391
16. Nakagohri T Asano T Kinoshita H Kenmochi T Urashima T Miura F Ochiai T Aggressive surgical resection for hilar-invasive and peripheral intrahepatic cholangiocarcinoma World J Surg 2003, 27(3):289-293 10.1007/ s00268-002-6696-7 12607053
17. Fiorentino M Altimari A D'Errico A Gabusi E Chieco P Masetti M Grigioni WF Low p27 expression is an independent predictor of survival for patients with either hilar or peripheral intrahepatic cholangiocarcinoma Clin Cancer Res 2001, 7(12):3994-3999 11751492
18. Shibahara H Tamada S Higashi M Goto M Batra SK Hollingsworth MA Imai K Yonezawa S MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type Hepatology 2004, 39(1):220-229 10.1002/hep.20031 14752841
19. Su MC Hsu C Kao HL Jeng YM CD24 expression is a prognostic factor in intrahepatic cholangiocarcinoma Cancer Lett 2006, 235(1):34-39 10.1016/ j.canlet.2005.03.059 16125303
20. Okaro AC Deery AR Hutchins RR Davidson BR The expression of antiapoptotic proteins Bcl-2, Bcl-X(L), and Mcl-1 in benign, dysplastic, and malignant biliary epithelium J Clin Pathol 2001, 54(12):927-932 1731328 11729212
21. Taniai M Grambihler A Higuchi H Werneburg N Bronk SF Farrugia DJ Kaufmann SH Gores GJ Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells Cancer Res 2004, 64(10):3517-3524 10.1158/0008-5472.CAN-03-2770 15150106
22. Takayama S Reed JC Homma S Heat-shock proteins as regulators of apoptosis Oncogene 2003, 22(56):9041-9047 10.1038/sj.onc.1207114 14663482
23. Garrido C Schmitt E Cande C Vahsen N Parcellier A Kroemer G HSP27 and HSP70: Potentially oncogenic apoptosis inhibitors Cell Cycle 2003, 2(6):579-584 14512773
24. Concannon CG Gorman AM Samali A On the role of Hsp27 in regulating apoptosis Apoptosis 2003, 8(1):61-70 10.1023/A:1021601103096 12510153
25. Charette SJ Landry J The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis Ann N Y Acad Sci 2000, 926:126-131 11193028
26. Arrigo AP Firdaus WJ Mellier G Moulin M Paul C Diaz-latoud C Kretz-remy C Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression Methods 2005, 35(2):126-138 10.1016/j.ymeth.2004.08.003 15649839
27. Pan G Ahn EY Chen Y Feng G Reddy V Jhala NC McDonald JM Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma Int J Oncol 2007, 31(4):843-850 17786316
28. Lebret T Watson RW Molinie V O'Neill A Gabriel C Fitzpatrick JM Botto H Heat shock proteins HSP27, HSP60, HSP70, and HSP90: Expression in bladder carcinoma Cancer 2003, 98(5):970-977 10.1002/cncr.11594 12942564
29. Kapranos N Kominea A Konstantinopoulos PA Savva S Artelaris S Vandoros G Sotiropoulou-Bonikou G Papavassiliou AG Expression of the 27-kDa heat shock protein (HSP27) in gastric carcinomas and adjacent normal, metaplastic, and dysplastic gastric mucosa, and its prognostic significance J Cancer Res Clin Oncol 2002, 128(8):426-432 10.1007/ s00432-002-0357-y 12200599
30. Langdon SP Rabiasz GJ Hirst GL King RJ Hawkins RA Smyth JF Miller WR Expression of the heat shock protein HSP27 in human ovarian cancer Clin Cancer Res 1995, 1(12):1603-1609 9815962
31. Elpek GO Karaveli S Simsek T Keles N Aksoy NH Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries Apmis 2003, 111(4):523-530 10.1034/j.1600-0463.2003.1110411.x 12780528
32. Geisler JP Tammela JE Manahan KJ Geisler HE Miller GA Zhou Z Wiemann MC HSP27 in patients with ovarian carcinoma: Still an independent prognostic indicator at 60 months follow-up Eur J Gynaecol Oncol 2004, 25(2):165-168 15032273
33. Mese H Sasaki A Nakayama S Yoshioka N Yoshihama Y Kishimoto K Matsumura T Prognostic significance of heat shock protein 27 (HSP27) in patients with oral squamous cell carcinoma Oncol Rep 2002, 9(2):341-344 11836604
34. Hsu PL Hsu SM Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease Cancer Res 1998, 58(23):5507-5513 9850087
35. Joo M Chi JG Lee H Expressions of HSP70 and HSP27 in hepatocellular carcinoma J Korean Med Sci 2005, 20(5):829-834 16224158
36. Lim SO Park SG Yoo JH Park YM Kim HJ Jang KT Cho JW Yoo BC Jung GH Park CK Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules World J Gastroenterol 2005, 11(14):2072-2079 15810071
37. Rocchi P Jugpal P So A Sinneman S Ettinger S Fazli L Nelson C Gleave M Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro BJU Int 2006, 98(5):1082-1089 10.1111/ j.1464-410X.2006.06425.x 16879439
38. Kamada M So A Muramaki M Rocchi P Beraldi E Gleave M Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells Mol Cancer Ther 2007, 6(1):299-308 10.1158/1535-7163.MCT-06-0417 17218637
39. Ciocca DR Calderwood SK Heat shock proteins in cancer: Diagnostic, prognostic, predictive, and treatment implications Cell Stress Chaperones 2005, 10(2):86-103 1176476 16038406 10.1379/CSC-99r.1
40. Jaattela M Escaping cell death: Survival proteins in cancer Exp Cell Res 1999, 248(1):30-43 10.1006/excr.1999.4455 10094811
41. Helmbrecht K Zeise E Rensing L Chaperones in cell cycle regulation and mitogenic signal transduction: A review Cell Prolif 2000, 33(6):341-365 10.1046/j.1365-2184.2000.00189.x 11101008
42. Jolly C Morimoto RI Role of the heat shock response and molecular chaperones in oncogenesis and cell death J Natl Cancer Inst 2000, 92(19):1564-1572 10.1093/jnci/92.19.1564 11018092
43. Thanner F Sutterlin MW Kapp M Rieger L Morr AK Kristen P Dietl J Gassel AM Muller T Heat shock protein 27 is associated with decreased survival in node-negative breast cancer patients Anticancer Res 2005, 25(3A):1649-1653 16033076
44. Geisler JP Geisler HE Tammela J Miller GA Wiemann MC Zhou Z A study of heat shock protein 27 in endometrial carcinoma Gynecol Oncol 1999, 72(3):347-350 10.1006/gyno.1998.5283 10053106
45. Zagorianakou N Ioachim E Mitselou A Kitsou E Zagorianakou P Makrydimas G Salmas M Agnantis NJ Immunohistochemical expression of heat shock protein 27, in normal hyperplastic and neoplastic endometrium: correlation with estrogen and progesterone receptor status, p53, pRb and proliferation associated indices (PCNA, MIB1) Eur J Gynaecol Oncol 2003, 24(3-4):299-304 12807244
46. Witkin SS Heat shock protein expression and immunity: Relevance to gynecologic oncology Eur J Gynaecol Oncol 2001, 22(4):249-256 11695802
47. Nakajima M Kuwano H Miyazaki T Masuda N Kato H Significant correlation between expression of heat shock proteins 27, 70 and lymphocyte infiltration in esophageal squamous cell carcinoma Cancer Lett 2002, 178(1):99-106 10.1016/S0304-3835(01)00825-4 11849747
48. Santarosa M Favaro D Quaia M Galligioni E Expression of heat shock protein 72 in renal cell carcinoma: Possible role and prognostic implications in cancer patients Eur J Cancer 1997, 33(6):873-877 10.1016/ S0959-8049(97)00002-6 9291808
49. Tsan MF Gao B Heat shock protein and innate immunity Cell Mol Immunol 2004, 1(4):274-279 16225770
50. Harada M Kimura G Nomoto K Heat shock proteins and the antitumor T cell response Biotherapy 1998, 10(3):229-235 10.1007/BF02678301 9559978
51. Multhoff G Heat shock proteins in immunity Handb Exp Pharmacol 2006, 172:279-304 16610364