Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses

International Journal of Cancer

Volumn 122, Issue 7, 2008, Pages 1573-1584

  Lee, Jin Hee ^a   Byun, Do Sun ^a   Lee, Min Goo ^a   Ryu, Byung Kyu ^a   Kang, Min Ju ^a   Chae, Kwon Seok ^a,b   Lee, Kil Yeon ^c   Kim, Hyo Jong ^c   Park, Heonyong ^d   Chi, Sung Gil ^a  

^a Korea University   (South Korea)

^b Kyungpook National University   (South Korea)

^c Kyung Hee University Hospital   (South Korea)

^d Dankook University   (South Korea)

Author keywords

Gastric cancer; hSRBC; p53; Promoter hypermethylation; Tumor suppressor gene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYCLIN DEPENDENT KINASE INHIBITOR 1; ETOPOSIDE; FLUOROURACIL; PROTEIN NOXA; PROTEIN P53; PUMA PROTEIN; TUMOR ANTIGEN; PRKCDBP PROTEIN, HUMAN; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ALLELE; APOPTOSIS; ARTICLE; BENIGN TUMOR; CANCER CELL CULTURE; CANCER STAGING; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CORRELATION ANALYSIS; CPG ISLAND; EPIGENETICS; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; GENE TARGETING; GENETIC ASSOCIATION; GENOTOXICITY; HSRBC GENE; HUMAN; HUMAN TISSUE; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; SOMATIC MUTATION; STOMACH CANCER; STRESS; TUMOR CELL; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION; ADENOCARCINOMA; ADENOMA; CANCER STEM CELL; DNA METHYLATION; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENETICS; HAMARTOMA; IMMUNOBLOTTING; METABOLISM; NICK END LABELING; NORTHERN BLOTTING; POLYP; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH TUMOR; TUMOR CELL LINE; XENOGRAFT;

ADENOCARCINOMA; ADENOMA; APOPTOSIS; BLOTTING, NORTHERN; CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; HAMARTOMA; HUMANS; IMMUNOBLOTTING; IN SITU NICK-END LABELING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASTIC STEM CELLS; POLYPS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 39649094115     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23166     Document Type: Article

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