Inhibitory deficits in attention-deficit/hyperactivity disorder are independent of basic processing efficiency and IQ

Journal of Neural Transmission

Volumn 115, Issue 2, 2008, Pages 261-268

  Bitsakou, P ^a   Psychogiou, L ^b   Thompson, M ^a   Sonuga Barke, E J S ^a,c,d  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NEW YORK UNIVERSITY   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Attention deficit hyperactivity disorder; Executive function; Go No Go task; Inhibitory control; Reaction time; Reaction time variability; Stop signal task; Stroop task

Indexed keywords

ADOLESCENCE; ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CHILDHOOD; CONTROLLED STUDY; EFFECT SIZE; FEMALE; HUMAN; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REACTION TIME; STATISTICAL ANALYSIS; TASK PERFORMANCE;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHILD; CHOICE BEHAVIOR; FEMALE; HUMANS; INHIBITION (PSYCHOLOGY); INTELLIGENCE; LEARNING DISORDERS; MALE; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TESTS; REACTION TIME; WECHSLER SCALES;

EID: 39549117412     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0828-z     Document Type: Article

References (43)

1. P Andreou BM Neale W Chen H Christiansen I Gabriels A Heise S Meidad UC Muller H Uebel T Banaschewski I Manor R Oades H Roeyers A Rothenberger P Sham HC Steinhausen P Asherson J Kuntsi 2007 Reaction time performance in ADHD: improvement under fast-incentive condition and familial effects Psychol Med 31 1 13
2. RA Barkley 1997 Behavioural inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD Psychol Bull 121 65 94
3. SK Berument M Rutter C Lord A Pickles A Bailey 1999 Autism screening questionnaire: diagnostic validity Br J Psychiatry 175 444 451
4. Bitsakou P (2007) Dissecting the neuropsychological structure of ADHD: inhibitory control and delay aversion. Unpublished doctoral thesis, University of Southampton, Southampton, UK
5. K Brookes X Xu W Chen K Zhou B Neale N Lowe R Aneley B Franke M Gill R Ebstein J Buitelaar 2006 The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes Mol Psychiatry 11 10 934 953
6. BJ Casey N Tottenham C Liston S Durston 2005 Imaging the developing brain: What have we learned about cognitive development? Trends Cognit Sci 9 3 104 110
7. FX Castellanos R Tannock 2002 Neuroscience of attention-deficit/ hyperactivity disorder: the search for endophenotypes Nat Rev Neurosci 3 617 628
8. FX Castellanos EJS Sonuga-Barke A Scheres A Di Martino C Hyde JR Walters 2005 Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability Biol Psychiatry 57 11 1416 1423
9. J Cohen 1992 A power primer Psychol Bull 112 155 159
10. K Conners 1996 Rating scales in ADHD Duke University Medical Centre Durham NC
11. AE Doyle S Faraone LJ Seidman EG Willcutt JT Nigg ID Waldman BF Pennington J Peart J Biederman 2005 Are endophenotypes based on measures of executive functions useful for molecular genetic studies of ADHD? J Child Psychol Psychiatry 46 7 774 803
12. R Drechsler D Brandeis M Földényi K Imhof H-C Steinhausen 2005 The course of neuropsychological functions in children with attention deficit hyperactivity disorder from late childhood to early adolescence J Child Psychol Psychiatry 46 8 824 836
13. BA Eriksen CW Eriksen 1974 Effects of noise letters upon identification of a target letter in a nonsearch task Percept Psychophys 16 143 149
14. TW Frazier HA Demaree EA Youngstrom 2004 Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder Neuropsychology 8 3 543 555
15. R Goodman 1997 The strengths and difficulties questionnaire: a research note J Child Psychol Psychiatry 38 581 586
16. SP Hinshaw ET Carte C Fan JS Jassy EB Owens 2007 Neuropsychological functioning of girls with attention-deficit/hyperactivity disorder followed prospectively into adolescence: evidence for continuing deficits? Neuropsychology 21 2 263 273
17. AM Hogan F Vergha-Khadem FJ Kirkham T Baldeweg 2005 Maturation of action monitoring from adolescents to adulthood: an ERP study Dev Sci 8 6 525 534
18. J Kuntsi J Oosterlaan J Stevenson 2001 Psychological mechanisms in hyperactivity: I. Response inhibition deficit, working memory impairment, delay aversion, or something else? J Child Psychol Psychiatry 42 199 210
19. J Kuntsi TC Eley A Taylor C Hughes P Asherson A Caspi TE Moffitt 2004 Co-occurrence of ADHD and low IQ has genetic origins Am J Med Genet B Neuropsychiatry Genet 124 1 41 47
20. GD Logan 1994 On the ability to inhibit thought and action: a users' guide to the stop signal paradigm D Dagenbach TH Carr Inhibitory processes in attention, memory, and language Academic Press San Diego 189 239
21. F Nichelli G Scala C Vago D Riva S Bulgheroni 2005 Age-related trends in stroop and conflicting motor response task findings Child Neuropsychol 11 431 443
22. JT Nigg 2001 Is ADHD a disinhibitory disorder? Psychol Bull 127 571 598
23. JT Nigg 2005 Neuropsychologic theory and finding in attention-deficit/ hyperactivity disorder: the state of the field and salient challenges from the coming decade Biol Psychiatry 57 1424 1435
24. JT Nigg 2006 What causes ADHD? Understanding what goes wrong and why Guilford Press New York
25. JT Nigg EG Willcutt AE Doyle EJS Sonuga-Barke 2005 Causal heterogeneity in attention-deficit/hyperactivity disorder: do we need neuropsychologically impaired subtypes? Biol Psychiatry 57 1224 1230
26. J Oosterlaan GD Logan J Sergeant 1998 Response inhibition in ADHD, CD, comorbid ADHD+CD, anxious, and control children: a meta-analysis of studies with the stop task J Child Psychol Psychiatry 39 411 425
27. TJ Polderman MF Gosso D Posthuma TC van Beijsterveldt P Heutink FC Verhulst DI Boomsma 2006 A longitudinal twin study on IQ, executive functioning, and attention problems during childhood and early adolescence Acta Neurol Belg 106 4 191 207
28. SM Rhodes DR Coghill K Matthews 2006 Acute neuropsychological effects of methylphenidate in stimulant drug-naïve boys with ADHD II - broader executive and non-executive domains J Child Psychol Psychiatry 47 11 1184 1194
29. CA Riccio S Homack KP Jarratt ME Wolfe 2006 Differences in academic and executive function domains among children with ADHD Predominantly Inattentive and Combined Types Arch Clin Neuropsychol 21 7 657 667
30. K Rubia E Taylor AB Smith H Oksannen S Overmeyer ET Bullmore S Newman 2001 Neuropsychological analyses of impulsiveness in childhood hyperactivity Br J Psychiatry 179 138 143
31. K Rubia A Smith E Taylor 2007 Performance of children with attention deficit hyperactivity disorder (ADHD) on a test battery of impulsiveness Child Neuropsychol 13 3 276 304
32. JM Sattler 1992 Assessment of children: WISC-III and WPPSI-R Supplement Sattler JM San Diego, CA
33. JA Sergeant 2005 Modelling ADHD: a critical appraisal of the cognitive-energetic model Biol Psychiatry 57 11 1248 1255
34. Sergeant JA, Willcutt E, Nigg J (in press) How clinically functional are executive function measures of ADHD? In: Shaffer D, Leibenluft E, Rohde LA, Sirovatka P, Regier DA (eds) Externalizing disorders of childhood: refining the research agenda for DSM-V. American Psychiatric Association, Arlington, VA
35. EJ Sonuga-Barke 2002 Psychological heterogeneity in AD/HD - a dual pathway model of behaviour and cognition Behav Brain Res 130 29 36
36. EJ Sonuga-Barke 2003 The dual pathway model of AD/HD: an elaboration of neuro-developmental characteristics Neurosci Biobehav Rev 27 593 604
37. EJ Sonuga-Barke 2005 Causal models of attention-deficit/hyperactivity disorder: from common simple deficits to multiple developmental pathways Biol Psychiatry 57 11 1231 1238
38. Sonuga-Barke EJ, Sergeant J, Nigg J, Willcutt E (2007) Executive dysfunction and delay aversion in ADHD: nosological and diagnostic implications. Child Adolesc Psychiatry Clin N Am (in press)
39. JR Stroop 1935 Studies of interference in serial verbal reactions J Expl Psychol 18 643 662
40. E Taylor G Sandberg G Thorley S Giles 1991 The epidemiology of childhood hyperactivity. Maudsley Monograph No. 33 Oxford University Press Oxford
41. R van Mourik J Oosterlaan JA Sergeant 2005 The Stroop revisited: a meta-analysis of interference control in AD/HD J Child Psychol Psychiatry 46 150 165
42. D Wechsler 1991 Wechsler Intelligence Scale for Children 3 Psychological Corporation San Antonio, TX
43. EG Willcutt AE Doyle JT Nigg SV Faraone BF Pennington 2005 Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review Biol Psychiatry 57 1336 1346