Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats

BJU International

Volumn 101, Issue 6, 2008, Pages 775-780

  Masuda, Hitoshi ^a,b   Kihara, Kazunori ^a   Saito, Kazutaka ^a   Matsuoka, Yoh ^a   Yoshida, Soichiro ^a   Chancellor, Michael B ^b   De Groat, William C ^b   Yoshimura, Naoki ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Bladder; C fibre; Cyclooxygenase; Hydrogen peroxide; Reactive oxygen species

Indexed keywords

CAPSAICIN; CATALASE; CHELATING AGENT; DEFEROXAMINE; DIMETHYLTHIOUREA; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INDOMETACIN; KETOPROFEN; PROSTAGLANDIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; URETHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYSTOMETRY; FEMALE; IN VIVO STUDY; KIDNEY ISCHEMIA; MICTURITION REFLEX; NONHUMAN; OVERACTIVE BLADDER; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; RAT; SENSITIZATION; SENSORY NERVE; STATISTICAL SIGNIFICANCE;

AFFERENT PATHWAYS; ANIMALS; ANTIOXIDANTS; CAPSAICIN; CATALASE; CYCLOOXYGENASE INHIBITORS; DEFEROXAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; INDOMETHACIN; KETOPROFEN; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SENSORY SYSTEM AGENTS; SIDEROPHORES; SUPEROXIDE DISMUTASE; THIOUREA; URINARY BLADDER; URINARY BLADDER, OVERACTIVE; URINATION;

EID: 39449137869     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2007.07310.x     Document Type: Article

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