Genomic alterations in lung adenocarcinomas detected by multicolor fluorescence in situ hybridization and comparative genomic hybridization

Cancer Genetics and Cytogenetics

Volumn 181, Issue 2, 2008, Pages 100-107

  Shen, Hua ^a   Zhu, Yu ^a   Wu, Yu jie ^a   Qiu, Hai rong ^a   Shu, Yong qian ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 16P; CHROMOSOME 17; CHROMOSOME 5; CHROMOSOME 6; CHROMOSOME ABERRATION; CHROMOSOME REARRANGEMENT; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENOMICS; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ADENOCARCINOMA; MALE; MULTICOLOR FLUORESCENCE IN SITU HYBRIDIZATION; PRIORITY JOURNAL;

ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; COLOR; GENOME, HUMAN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LUNG NEOPLASMS; NUCLEIC ACID HYBRIDIZATION;

EID: 39449137818     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2007.11.012     Document Type: Article

References (34)

1. Tonon G., Wong K.K., Maulik G., Brennan C., Feng B., Zhang Y., Khatry D.B., Protopopov A., You M.J., Aguirre A.J., Martin E.S., Yang Z., Ji H., Chin L., and Depinho R.A. High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A 102 (2005) 9625-9630
2. Travis W.D., Brambilla E., Muller-Hermelink H.K., and Harris C.C. Pathology and genetics of tumours of the lung, pleura, thymus and heart. World Health Organization Classification of Tumours (2004), IARC Press, Lyon
3. Mantripragada K.K., Buckley P.G., de Stahl T.D., and Dumanski J.P. Genomic microarrays in the spotlight. Trends Genet 20 (2004) 87-94
4. Balsara B.R., and Testa J.R. Chromosomal imbalances in human lung cancer. Oncogene 21 (2002) 6877-6883
5. Kallioniemi A., Kallioniemi O.P., Sudar D., Rutovitz D., Gray J.W., Waldman F., and Pinkel D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258 (1992) 818-821
6. Balsara B.R., Sonoda G., du Manoir S., Siegfried J.M., Gabrielson E., and Testa J.R. Comparative genomic hybridization analysis detects frequent, often high-level, overrepresentation of DNA sequences at 3q, 5p, 7p, and 8q in human non-small cell lung carcinomas. Cancer Res 57 (1997) 2116-2120
7. Petersen I., Bujard M., Petersen S., Wolf G., Goeze A., Schwendel A., Langreck H., Gellert K., Reichel M., Just K., du Manoir S., Cremer T., Dietel M., and Ried T. Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung. Cancer Res 57 (1997) 2331-2335
8. Björkqvist A.M., Husgafvel-Pursiainen K., Anttila S., Karjalainen A., Tammilehto L., Mattson K., Vainio H., and Knuutila S. DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma. Genes Chromosomes Cancer 22 (1998) 79-82
9. Speicher M.R., Petersen S., Uhrig S., Jentsch I., Fauth C., Eils R., and Petersen I. Analysis of chromosomal alterations in non-small cell lung cancer by multiplex-FISH, comparative genomic hybridization, and multicolor bar coding. Lab Inves 80 (2000) 1031-1041
10. Speicher M.R., Gwyn Ballard S., and Ward D.C. Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nat Genet 12 (1996) 368-375
11. Ashman J.N.E., Brigham J., Cowen M.E., Bahia H., Greenman J., Lind M., and Cawkwell L. Chromosomal alterations in small cell lung cancer revealed by multicolour fluorescent in situ hybridization. Int J Cancer 102 (2002) 230-236
12. ISCN 1995: an international system for human cytogenetic nomenclature (1995). In: Mitelman F. (Ed) (1995), S. Karger, Basel
13. Gunawan B., Schulten H.J., von Heydebreck A., Schmidt B., Enders C., Höer J., Langer C., Schüler P., Schindler C.G., Kuhlgatz J., and Füzesi L. Site-independent prognostic value of chromosome 9q loss in primary gastrointestinal stromal tumours. J Pathol 202 (2004) 421-429
14. Gunawan B., Mirzaie M., Schulten H.-J., Heidrich B., and Füzesi L. Molecular cytogenetic analysis of two primary squamous cell carcinomas of the lung using multicolor fluorescence in situ hybridization. Virchows Arch 439 (2001) 85-89
15. Luk C., Tsao M.-S., Bayani J., Shepherd F., and Squire J.A. Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization. Cancer Genet Cytogenet 125 (2001) 87-99
16. Balsara B.R., and Testa J.R. Chromosomal imbalances in human lung cancer. Oncogene 21 (2002) 6877-6883
17. Baudis M. Online database and bioinformatics toolbox to support data mining in cancer cytogenetics. Biotechniques 40 (2006) 272-296
18. Tonon G., Wong K.K., Maulik G., Brennan C., Feng B., Zhang Y., Khatry D.B., Protopopov A., You M.J., Aguirre A.J., Martin E.S., Yang Z., Ji H., Chin L., and Depinho R.A. High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A 102 (2005) 9625-9630
19. Astrinidis A., Khare L., Carsillo T., Smolarek T., Au K.S., Northrup H., and Henske E.P. Mutational analysis of the tuberous sclerosis gene TSC2 in patients with pulmonary lymphangioleiomyomatosis. J Med Genet 37 (2000) 55-57
20. Calvo R., West J., Franklin W., Erickson P., Bemis L., Li E., Helfrich B., Bunn P., Roche J., Brambilla E., Rosell R., Gemmill R.M., and Drabkin H.A. Altered HOX and WNT7A expression in human lung cancer. Proc Natl Acad Sci U S A 97 (2000) 12776-12781
21. Chénais B., Derjuga A., Massrieh W., Red-Horse K., Bellingard V., Fisher S.J., and Blank V. Functional and placental expression analysis of the human NRF3 transcription factor. Mol Endocrinol 19 (2005) 125-137
22. Sato J., Sata M., Nakamura H., Inoue S., Wada T., Takabatake N., Otake K., Tomoike H., and Kubota I. Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma. Int J Cancer 106 (2003) 863-870
23. Paez J.G., Jänne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., Herman P., Kaye F.J., Lindeman N., Boggon T.J., Naoki K., Sasaki H., Fujii Y., Eck M.J., Sellers W.R., Johnson B.E., and Meyerson M. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304 (2004) 1497-1500
24. Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., Harris P.L., Haserlat S.M., Supko J.G., Haluska F.G., Louis D.N., Christiani D.C., Settleman J., and Haber D.A. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib. N Engl J Med 350 (2004) 2129-2139
25. Hirsch F.R., and Bunn Jr. P.A. Epidermal growth factor receptor inhibitors in lung cancer: smaller or larger molecules, selected or unselected populations?. J Clin Oncol 23 (2005) 9044-9047
26. Garnis C., Lockwood W.W., Vucic E., Ge Y., Girard L., Minna J.D., Gazdar A.F., Lam S., MacAulay C., and Lam W.L. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer 118 (2006) 1556-1564
27. Petersen S., Aninat-Meyer M., Schlüns K., Gellert K., Dietel M., and Petersen I. Chromosomal alterations in the clonal evolution to the metastatic stage of squamous cell carcinomas of the lung. Br J Cancer 82 (2000) 65-73
28. Massion P.P., Taflan P.M., Jamshedur Rahman S.M., Yildiz P., Shyr Y., Edgerton M.E., Westfall M.D., Roberts J.R., Pietenpol J.A., Carbone D.P., and Gonzalez A.L. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res 63 (2003) 7113-7121
29. Yokoi S., Yasui K., Iizasa T., Imoto I., Fujisawa T., and Inazawa J. TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers. Clin Cancer Res 9 (2003) 4705-4713
30. Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., Yan H., Gazdar A., Powell S.M., Riggins G.J., Willson J.K., Markowitz S., Kinzler K.W., Vogelstein B., and Velculescu V.E. High frequency of mutations of the PIK3CA gene in human cancers. Science 304 (2004) 554
31. Tan D., Deeb G., Wang J., Slocum H.K., Winston J., Wiseman S., Beck A., Sait S., Anderson T., Nwogu C., Ramnath N., and Loewen G. HER-2/neu protein expression and gene alteration in stage I-IIIA non-small-cell lung cancer: a study of 140 cases using a combination of high throughput tissue microarray, immunohistochemistry, and fluorescent in situ hybridization. Diagn Mol Pathol 12 (2003) 201-211
32. Wikman H., Nymark P., Väyrynen A., Jarmalaite S., Kallioniemi A., Salmenkivi K., Vainio-Siukola K., Husgafvel-Pursiainen K., Knuutila S., Wolf M., and Anttila S. CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Genes Chromosomes Cancer 42 (2005) 193-199
33. Yakut T., Egeli U., and Gebitekin C. Investigation of c-myc and p53 gene alterations in the tumor and surgical borderline tissues of NSCLC and effects on clinicopathologic behavior: by the FISH technique. Lung 181 (2003) 245-258
34. Goeze A., Schlüns K., Wolf G., Thäsler Z., Petersen S., and Petersen I. Chromosomal imbalances of primary and metastatic lung adenocarcinomas. J Pathol 196 (2002) 8-16