Adenosine prompts the heart to recruit endothelial progenitors

Circulation Research

Volumn 102, Issue 3, 2008, Pages 280-282

  Shen, Jianzhong ^a   DiCorleto, Paul E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Adenosine; Endothelial progenitor cells; Microvasculature; Receptors

Indexed keywords

ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE;

CARDIOVASCULAR SYSTEM; CELL GROWTH; CELL MEMBRANE; CORONARY ARTERY DILATATION; EDITORIAL; ENDOTHELIUM CELL; HEART FUNCTION; HUMAN; HYPOXIA; NONHUMAN; NUTRITION; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

ADENOSINE; ANIMALS; CELL ADHESION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; MEMBRANE GLYCOPROTEINS; MICE; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; P-SELECTIN; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2B; STEM CELL TRANSPLANTATION; STEM CELLS; VASODILATOR AGENTS;

EID: 39449128093     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.107.170522     Document Type: Editorial

References (23)

1. Drury AN, Szent-Györgyi A. The physiological activity of adenine compounds with special reference to their action upon the mammalian heart. J Physiol. 1929;68:213-237.
2. Berne RM, Knabb RM, Ely SW, Rubio R. Adenosine in the local regulation of blood flow: a brief overview. Fed Proc. 1983;42:3136-3142.
3. Feigl EO. Berne's adenosine hypothesis of coronary blood flow control. Am J Physiol. 2004;287:H1891-H1894.
4. Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev. 2001;53:527-552.
5. Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K. The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J Clin Invest. 2006;116:1913-1923.
6. Yoshioka K, Saitoh O, Nakata H. Heteromeric association creates a P2Y-like adenosine receptor. Proc Natl Acad Sci U S A. 2001;98:7617-7622.
7. 1 receptors form functionally interacting heteromeric complexes. Proc Natl Acad Sci U S A. 2000;97:8606-8611.
8. 2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J Biol Chem. 2003;278:46741-46749.
9. Tabrizchi R, Bedi S. Pharmacology of adenosine receptors in the vasculature. Pharmacol Ther. 2001;91:133-147.
10. Hansen PB, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol. 2003;285:F590-F599.
11. Tawfik HE, Teng B, Morrison RR, Schnermann J, Mustafa SJ. Role of A1 adenosine receptor in the regulation of coronary flow. Am J Physiol. 2006;291:H467-H472.
12. 2B receptors in angiogenic factor regulation. Circ Res. 2002;90:531-538.
13. 2B receptors in cultured human and porcine coronary artery endothelial cells. Am J Physiol. 2000;279:H650-H656.
14. Linden J. Autoregulation of cyclic AMP in vascular smooth muscle: a role for adenosine receptors. Mol Pharmacol. 2002;62:969-970.
15. Adair TH. Growth regulation of the vascular system: an emerging role for adenosine. Am J Physiol. 2005;289:R283-R296.
16. Dubey RK, Gillespie DG, Jackson EK. A2B adenosine receptors stimulate growth of porcine and rat arterial endothelial cells. Hypertension. 2002;39:530-535.
17. 2b receptors mediate antimitogenesis in vascular smooth muscle cells. Hypertension. 2000;35:267-272.
18. 1 adenosine receptor. Circ Res. 2005;96:982-990.
19. 1 adenosine receptor. Circ Res. 2005;97:574-582.
20. Auchampach JA. Adenosine receptors and angiogenesis. Circ Res. 2007;101:1075-1077.
21. Clark AN, Youkey R, Liu X, Jia L, Blatt R, Day YJ, Sullivan GW, Linden J, Tucker AL. A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res. 2007;101:1130-1138.
22. Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, Cronstein BN. Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A2A receptors. Am J Pathol. 2002;160:2009-1018.
23. Ryzhov S, Solenkova NV, Goldstein AE, Lamparter M, Fleenor T, Young PP, Greelish JP, Byrne JG, Vaughan DE, Biaggioni I, Hatzopoulos AK, Feoktistov I. Adenosine receptor-mediated adhesion of endothelial progenitors to cardiac microvascular endothelial cells. Circ Res. 2008;102:356-363.