How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia?

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 24, Issue 8, 2004, Pages 1334-1336

  Jirholt, Pernilla ^a   Adiels, Martin ^a   Borén, Jan ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B100; ENZYME PRECURSOR; FAT DROPLET; INTERMEDIATE DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MUTANT PROTEIN; NEURAL APOPTOSIS REGULATED CONVERTASE 1; PROTEINASE; SECRETORY PROTEIN; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

AMINO ACID SUBSTITUTION; APOPTOSIS; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE DISORDER; CHOLESTEROL BLOOD LEVEL; EDITORIAL; ENZYME ACTIVITY; FAMILIAL HYPERCHOLESTEROLEMIA; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC DISORDER; GENETIC LINKAGE; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN SECRETION; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

AMINO ACID SUBSTITUTION; APOLIPOPROTEIN B-100; APOLIPOPROTEINS B; CHOLESTEROL ESTERS; GENES, DOMINANT; GENETIC HETEROGENEITY; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; LIPOPROTEINS; LIPOPROTEINS, IDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MUTATION, MISSENSE; POINT MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; SERINE ENDOPEPTIDASES;

EID: 3943075161     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000133682.97348.ff     Document Type: Editorial

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