메뉴 건너뛰기




Volumn 29, Issue 6, 2004, Pages 574-580

Vinflunine: Antimitotic vinca alkaloid

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CISPLATIN; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; L 0070; MITOMYCIN C; NAVELBINE; PLATINUM DERIVATIVE; TAXANE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG; VINCA ALKALOID; VINFLUNINE;

EID: 3943060241     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2004.029.06.816574     Document Type: Article
Times cited : (14)

References (43)
  • 1
    • 3943110888 scopus 로고    scopus 로고
    • (Pierre Fabre Médicament). Novel antimitotic binary alkaloid derivs. extracted from Catharanthus roseus. EP 0710240, FR 2707988, US 5620985, WO 9503312
    • Jacquesy, J.-C., Fahy, J., Berrier, C., Bigg, D., Jouannetaud, M.-P., Zunino, F., Kruczynski, A., Kiss, R. (Pierre Fabre Médicament). Novel antimitotic binary alkaloid derivs. extracted from Catharanthus roseus. EP 0710240, FR 2707988, US 5620985, WO 9503312.
    • Jacquesy, J.-C.1    Fahy, J.2    Berrier, C.3    Bigg, D.4    Jouannetaud, M.-P.5    Zunino, F.6    Kruczynski, A.7    Kiss, R.8
  • 4
    • 3943084790 scopus 로고    scopus 로고
    • (Pierre Fabre Médicament). Vinca alkaloid antimitotic halogenated derivs. EP 0975640, JP 2001518892, US 6127377, WO 9845301
    • Duflos, A., Fahy, J., Thillaye du Boulay, V., Barret, J.-M., Hill, B. (Pierre Fabre Médicament). Vinca alkaloid antimitotic halogenated derivs. EP 0975640, JP 2001518892, US 6127377, WO 9845301.
    • Duflos, A.1    Fahy, J.2    Thillaye Du Boulay, V.3    Barret, J.-M.4    Hill, B.5
  • 5
    • 0032031453 scopus 로고    scopus 로고
    • Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid
    • Kruczynski, A., Barret, J.-M., Etiévant, C., Colpaert, F., Fahy, J., Hill, B.T. Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid. Biochem Pharmacol 1998, 55: 635-48.
    • (1998) Biochem Pharmacol , vol.55 , pp. 635-648
    • Kruczynski, A.1    Barret, J.-M.2    Etiévant, C.3    Colpaert, F.4    Fahy, J.5    Hill, B.T.6
  • 6
    • 0031780236 scopus 로고    scopus 로고
    • A comparison of thermodynamic parameters for vinorelbine- and vinf/unine-induced tubulin self-association by sedimentation velocity
    • Lobert, S., Ingram, J.W., Hill, B.T., Correia, JJ. A comparison of thermodynamic parameters for vinorelbine- and vinf/unine-induced tubulin self-association by sedimentation velocity. Mol Pharmacol 1998, 53: 908-15.
    • (1998) Mol Pharmacol , vol.53 , pp. 908-915
    • Lobert, S.1    Ingram, J.W.2    Hill, B.T.3    Correia, J.J.4
  • 7
    • 0032825746 scopus 로고    scopus 로고
    • Vinflunine, a new vinca alkaloid: Cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells
    • Jean-Decoster, C., Brichese, L., Barret, J.-M., Tollon, Y., Kruczynski, A., Hill, B.T., Wright, M. Vinflunine, a new vinca alkaloid: Cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells. Anti-Cancer Drugs 1999, 10: 537-43.
    • (1999) Anti-Cancer Drugs , vol.10 , pp. 537-543
    • Jean-Decoster, C.1    Brichese, L.2    Barret, J.-M.3    Tollon, Y.4    Kruczynski, A.5    Hill, B.T.6    Wright, M.7
  • 8
    • 0034773326 scopus 로고    scopus 로고
    • Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties
    • Kruczynski, A., Hill, B.T. Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties. Crit Rev Oncol Hematol 2001, 40: 159-73.
    • (2001) Crit Rev Oncol Hematol , vol.40 , pp. 159-173
    • Kruczynski, A.1    Hill, B.T.2
  • 9
    • 0034665163 scopus 로고    scopus 로고
    • Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules
    • Ngan, V.K., Bellman, K., Panda, D., Hill, B.T., Jordan, M.A., Wilson, L. Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules. Cancer Res 2000, 60: 5045-51.
    • (2000) Cancer Res , vol.60 , pp. 5045-5051
    • Ngan, V.K.1    Bellman, K.2    Panda, D.3    Hill, B.T.4    Jordan, M.A.5    Wilson, L.6
  • 10
    • 0034960408 scopus 로고    scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative Vinflunine
    • Ngan, V.K., Bellman, K., Hill, B.T., Wilson, L., Jordan, M.A. Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative Vinflunine. Mol Pharmacol 2001, 60: 225-32.
    • (2001) Mol Pharmacol , vol.60 , pp. 225-232
    • Ngan, V.K.1    Bellman, K.2    Hill, B.T.3    Wilson, L.4    Jordan, M.A.5
  • 11
    • 0038674316 scopus 로고    scopus 로고
    • The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics
    • Okouneva, T., Hill, B.T., Wilson, L., Jordan, M.A. The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics. Mol Cancer Ther 2003, 2: 427-36.
    • (2003) Mol Cancer Ther , vol.2 , pp. 427-436
    • Okouneva, T.1    Hill, B.T.2    Wilson, L.3    Jordan, M.A.4
  • 12
    • 0037033711 scopus 로고    scopus 로고
    • Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development
    • Kruczynski, A., Etiévant, C., Perrin, D., Chansard, N., Duflos, A., Hill, B.T. Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development. Br J Cancer 2002, 86: 143-50.
    • (2002) Br J Cancer , vol.86 , pp. 143-150
    • Kruczynski, A.1    Etiévant, C.2    Perrin, D.3    Chansard, N.4    Duflos, A.5    Hill, B.T.6
  • 15
    • 0033105721 scopus 로고    scopus 로고
    • Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts
    • Hill, B.T., Fiebig, H.-H., Waud, W.R., Poupon, M.-F., Colpaert, F., Kruczynski, A. Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts. Eur J Cancer 1999, 35: 512-20.
    • (1999) Eur J Cancer , vol.35 , pp. 512-520
    • Hill, B.T.1    Fiebig, H.-H.2    Waud, W.R.3    Poupon, M.-F.4    Colpaert, F.5    Kruczynski, A.6
  • 16
    • 3943101332 scopus 로고    scopus 로고
    • Anticancer activity of vinflunide, a novel fluorinated vinca alkaloid in human gastric and melanoma models
    • Abst 1999
    • Fiebig, H.H., Hill, B.T., Burger, A.M., Gyselinck, N., Vincenti, M. Anticancer activity of vinflunide, a novel fluorinated vinca alkaloid in human gastric and melanoma models. Proc Am Assoc Cancer Res 2001, 42: Abst 1999.
    • (2001) Proc Am Assoc Cancer Res , vol.42
    • Fiebig, H.H.1    Hill, B.T.2    Burger, A.M.3    Gyselinck, N.4    Vincenti, M.5
  • 17
    • 3943052665 scopus 로고    scopus 로고
    • Anticancer activity of vinflunine, a novel fluorinated vinca alkaloid in human pancreas, renal and non-small cell (NSCL) lung tumor xenografts
    • Abst 1331
    • Fiebig, H.-H., Hill, B.T., Burger, A.M., Gyselinck, N., Vincenti, M. Anticancer activity of vinflunine, a novel fluorinated vinca alkaloid in human pancreas, renal and non-small cell (NSCL) lung tumor xenografts. Proc Am Assoc Cancer Res 2002, 43: Abst 1331.
    • (2002) Proc Am Assoc Cancer Res , vol.43
    • Fiebig, H.-H.1    Hill, B.T.2    Burger, A.M.3    Gyselinck, N.4    Vincenti, M.5
  • 18
    • 3943082709 scopus 로고    scopus 로고
    • Significant antiangiogenic activity and marked inhibition of growth of an orthotopic colon cancer model and colon cancer liver métastases by vinflunine, the most recent vinca alkaloid in clinical development
    • Abst 1332
    • Kruczynski, A., Ricome, C., Astruc, J., Chazottes, E., Dejean, C., Berrichon, G., Hill, B. Significant antiangiogenic activity and marked inhibition of growth of an orthotopic colon cancer model and colon cancer liver métastases by vinflunine, the most recent vinca alkaloid in clinical development. Proc Am Assoc Cancer Res 2002, 43: Abst 1332.
    • (2002) Proc Am Assoc Cancer Res , vol.43
    • Kruczynski, A.1    Ricome, C.2    Astruc, J.3    Chazottes, E.4    Dejean, C.5    Berrichon, G.6    Hill, B.7
  • 20
    • 0035986530 scopus 로고    scopus 로고
    • Higher antitumor activity of vinflunine than vinorelbine against an orthotopic marine model of transitional cell carcinoma of the bladder
    • Bonfil, R.D., Russo, D.M., Binda, M.M., Delgado, F.M., Vincenti, M. Higher antitumor activity of vinflunine than vinorelbine against an orthotopic marine model of transitional cell carcinoma of the bladder. Urol Oncol 2002, 7: 159-66.
    • (2002) Urol Oncol , vol.7 , pp. 159-166
    • Bonfil, R.D.1    Russo, D.M.2    Binda, M.M.3    Delgado, F.M.4    Vincenti, M.5
  • 22
    • 0031820395 scopus 로고    scopus 로고
    • Vinflunine (20′,20′-difluoro-3′,4′- dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro
    • Etievant, C., Barret, J.-M., Kruczynski, A., Perrin, D., Hill, B.T. Vinflunine (20′,20′-difluoro-3′,4′-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro. Invest New Drugs 1998, 16: 3-17.
    • (1998) Invest New Drugs , vol.16 , pp. 3-17
    • Etievant, C.1    Barret, J.-M.2    Kruczynski, A.3    Perrin, D.4    Hill, B.T.5
  • 23
    • 0034918410 scopus 로고    scopus 로고
    • Markedly diminished drug resistance-inducing properties of vinflunine (20′,20′-difluoro-3′,4′-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro
    • Etiévant, C., Kruczynski, A., Barret, J.-M., Tait, A.S., Kavallaris, M., Hill, B.T. Markedly diminished drug resistance-inducing properties of vinflunine (20′,20′-difluoro-3′,4′- dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro. Cancer Chemother Pharmacol 2001, 48: 62-70.
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 62-70
    • Etiévant, C.1    Kruczynski, A.2    Barret, J.-M.3    Tait, A.S.4    Kavallaris, M.5    Hill, B.T.6
  • 24
    • 0034074044 scopus 로고    scopus 로고
    • In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs
    • Barret, J.-M., Etiévant, C., Hill, B.T. In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs. Cancer Chemother Pharmacol 2000, 45: 471-6.
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 471-476
    • Barret, J.-M.1    Etiévant, C.2    Hill, B.T.3
  • 25
    • 3943075763 scopus 로고    scopus 로고
    • Synergistic effects of the farnesyltransferase inhibitor SCH 66336 and novel Vinca alkaloids in A549 non-small cell lung cancer cells in vitro
    • (Nov 17-21, Boston), Abst 269
    • Etievant, C., Barret, J.M., Cabrol, N., Offrete, V., Hill, B.T. Synergistic effects of the farnesyltransferase inhibitor SCH 66336 and novel Vinca alkaloids in A549 non-small cell lung cancer cells in vitro. AACR-NCI-EORTC Int Conf Mol Targets Cancer Ther (Nov 17-21, Boston) 2003, Abst 269.
    • (2003) AACR-NCI-EORTC Int Conf Mol Targets Cancer Ther
    • Etievant, C.1    Barret, J.M.2    Cabrol, N.3    Offrete, V.4    Hill, B.T.5
  • 26
    • 0842311660 scopus 로고    scopus 로고
    • Vinflunine potentiates the activity of cisplatin but not 5-fluorouracil in a transplantable murine adenocarcinoma model
    • Shnyder, S.D., Cooper, P.A., Gyselinck, N., Hill, B.T., Double, J.A., Bibby, M.C. Vinflunine potentiates the activity of cisplatin but not 5-fluorouracil in a transplantable murine adenocarcinoma model. Anticancer Res 2003, 23: 4815-20.
    • (2003) Anticancer Res , vol.23 , pp. 4815-4820
    • Shnyder, S.D.1    Cooper, P.A.2    Gyselinck, N.3    Hill, B.T.4    Double, J.A.5    Bibby, M.C.6
  • 27
    • 0035150786 scopus 로고    scopus 로고
    • Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model
    • Holwell, S.E., Hill, B.T., Bibby, M.C. Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model. Br J Cancer 2001, 84: 290-5.
    • (2001) Br J Cancer , vol.84 , pp. 290-295
    • Holwell, S.E.1    Hill, B.T.2    Bibby, M.C.3
  • 28
    • 3943070330 scopus 로고    scopus 로고
    • In vitro and in vivo synergistic and additive effects of vinflunine, a novel fluorinated Vinca alkaloid currently in phase II trials in combination with other anticancer drugs
    • Abst 2138
    • Hill, B.T, Barret, J.-M., Fahy, J., Kruczynski, A. In vitro and in vivo synergistic and additive effects of vinflunine, a novel fluorinated Vinca alkaloid currently in phase II trials in combination with other anticancer drugs. Proc Am Soc Clin Oncol 2001, 20(Part 2): Abst 2138.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 2
    • Hill, B.T.1    Barret, J.-M.2    Fahy, J.3    Kruczynski, A.4
  • 29
    • 27144504311 scopus 로고    scopus 로고
    • Markedly augmented in vivo experimental antitumor activity with vinflunine, the most recent Vinca alkaloid to show activity in phase I clinical trials, when combined with DNA damaging anticancer agents
    • Abst 1333
    • Kruczynski, A., Ricome, C., Astruc, J., Chazottes, E., Dejean, C., Hill, B.T. Markedly augmented in vivo experimental antitumor activity with vinflunine, the most recent Vinca alkaloid to show activity in phase I clinical trials, when combined with DNA damaging anticancer agents. Proc Am Assoc Cancer Res 2002, 43: Abst 1333.
    • (2002) Proc Am Assoc Cancer Res , vol.43
    • Kruczynski, A.1    Ricome, C.2    Astruc, J.3    Chazottes, E.4    Dejean, C.5    Hill, B.T.6
  • 31
    • 0037819331 scopus 로고    scopus 로고
    • Phase I pharmacokinetic study of the new vinca alkaloid vinflunine administered as a 10-min infusion every 3 weeks in patients with advanced solid tumours
    • Bennouna, J., Fumoleau, P., Armand, J.-P, Raymond, E., Campone, M., Delgado, F.M., Puozzo, C., Marty, M. Phase I and pharmacokinetic study of the new vinca alkaloid vinflunine administered as a 10-min infusion every 3 weeks in patients with advanced solid tumours. Ann Oncol 2003, 14: 630-7.
    • (2003) Ann Oncol , vol.14 , pp. 630-637
    • Bennouna, J.1    Fumoleau, P.2    Armand, J.-P.3    Raymond, E.4    Campone, M.5    Delgado, F.M.6    Puozzo, C.7    Marty, M.8
  • 32
    • 0001571414 scopus 로고    scopus 로고
    • Pharmacokinetics of vinflunine, a novel vinca alkaloid, during the phase I dose escalation study (D1 Q 3 weeks)
    • Abst 2050
    • Armand, J-P., Fumoleau, P., Marty, M., Variol, P., Pinel, M.-C., Picard, M., Puozzo, C. Pharmacokinetics of vinflunine, a novel vinca alkaloid, during the phase I dose escalation study (D1 Q 3 weeks). Proc Am Assoc Cancer Res 2001, 42: Abst 2050.
    • (2001) Proc Am Assoc Cancer Res , vol.42
    • Armand, J.-P.1    Fumoleau, P.2    Marty, M.3    Variol, P.4    Pinel, M.-C.5    Picard, M.6    Puozzo, C.7
  • 34
    • 3943102041 scopus 로고    scopus 로고
    • A phase I pharmacokinetic study of vinflunine given on days 1 and 8 every 3 weeks
    • Abst 2070
    • Zorza, G., Johnson, P., Judson, I., Fumoleau, P., Diamand, F. A phase I pharmacokinetic study of vinflunine given on days 1 and 8 every 3 weeks. Proc Am Soc Clin Oncol 2001, 20(Part 2): Abst 2070.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 2
    • Zorza, G.1    Johnson, P.2    Judson, I.3    Fumoleau, P.4    Diamand, F.5
  • 35
    • 3943095303 scopus 로고    scopus 로고
    • A phase I pharmacokinetic study of vinflunine given on a weekly schedule
    • Abst 2107
    • Puozzo, C., Vermorken, J.B., Bauer, J., Bugat, R., Pinel, M.-C. A phase I pharmacokinetic study of vinflunine given on a weekly schedule. Proc Am Soc Clin Oncol 2001, 20(Part 2): Abst 2107.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 2
    • Puozzo, C.1    Vermorken, J.B.2    Bauer, J.3    Bugat, R.4    Pinel, M.-C.5
  • 37
    • 4243813549 scopus 로고    scopus 로고
    • Phase I study of vinflunine given as a 10 minute intravenous (IV) infusion on a weekly schedule in patients (pts) with advanced solid tumors
    • Abst 441
    • Delord, J.P., Stupp, R., Pinel, M.C., Nguyen, L., Vermerken, J.B. Phase I study of vinflunine given as a 10 minute intravenous (IV) infusion on a weekly schedule in patients (pts) with advanced solid tumors. Proc Am Soc Clin Oncol 2001, 20(Part 1): Abst 441.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 1
    • Delord, J.P.1    Stupp, R.2    Pinel, M.C.3    Nguyen, L.4    Vermerken, J.B.5
  • 38
    • 27144495909 scopus 로고    scopus 로고
    • Phase I study of IV vinflunine given on a weekly schedule in previously untreated patients (pts) with advanced solid tumors
    • Abst 887
    • Vermorken, J.B., Stupp, R., Nguyen, L., Pinel, M.-C., Delord, J.-P. Phase I study of IV vinflunine given on a weekly schedule in previously untreated patients (pts) with advanced solid tumors. Proc Am Soc Clin Oncol 2003, 22: Abst 887.
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Vermorken, J.B.1    Stupp, R.2    Nguyen, L.3    Pinel, M.-C.4    Delord, J.-P.5
  • 39
    • 2942550368 scopus 로고    scopus 로고
    • Preliminary results of a phase II study testing intravenous (iv) vinflunine (VFL) as second line therapy in patients with advanced transitional cell cancer (TCC) of the bladder
    • Abst 1571
    • Bui, B., Theodore, C., Culine, S., De Santis, M., Demkow, T., Lorenz, J., Rolland, F., Fabry, F., Puget, J.C., James, N. Preliminary results of a phase II study testing intravenous (iv) vinflunine (VFL) as second line therapy in patients with advanced transitional cell cancer (TCC) of the bladder. Proc Am Soc Clin Oncol 2003, 22: Abst 1571.
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Bui, B.1    Theodore, C.2    Culine, S.3    De Santis, M.4    Demkow, T.5    Lorenz, J.6    Rolland, F.7    Fabry, F.8    Puget, J.C.9    James, N.10
  • 40
    • 3943091822 scopus 로고    scopus 로고
    • Preliminary results of a phase II study of intravenous vinflunine as second line therapy in patients with metastatic breast cancer after anthracycline-taxane based regimen failure
    • (Dec 3-6, San Antonio), Abst 355
    • Campone, M., Vorobiof, D., Cotes-Runes, H., Verrill, M., Khoo, K.S., Slabber, C.R, Caroff, I., Pouget, J.C., Pumoleau, P. Preliminary results of a phase II study of intravenous vinflunine as second line therapy in patients with metastatic breast cancer after anthracycline-taxane based regimen failure. 26th Annu San Antonio Breast Cancer Symp (Dec 3-6, San Antonio) 2003, Abst 355.
    • (2003) 26th Annu San Antonio Breast Cancer Symp
    • Campone, M.1    Vorobiof, D.2    Cotes-Runes, H.3    Verrill, M.4    Khoo, K.S.5    Slabber, C.R.6    Caroff, I.7    Pouget, J.C.8    Pumoleau, P.9
  • 41
    • 3943083388 scopus 로고    scopus 로고
    • Phase I/II and pharmacokinetic study of vinflunine (VFL) in combination with cisplatin (CDDP) for treatment of advanced non-small cell lung cancer (NSCLC) in chemonaive patients: Preliminary results
    • Abst 803
    • Krzakowski, M., Ramlau, R., Pinel, M., Zorza, G., Colin, C., Souquet, P. Phase I/II and pharmacokinetic study of vinflunine (VFL) in combination with cisplatin (CDDP) for treatment of advanced non-small cell lung cancer (NSCLC) in chemonaive patients: Preliminary results. Eur J Cancer - Suppl 2003, 1(Suppl. 5): Abst 803.
    • (2003) Eur J Cancer - Suppl , vol.1 , Issue.SUPPL. 5
    • Krzakowski, M.1    Ramlau, R.2    Pinel, M.3    Zorza, G.4    Colin, C.5    Souquet, P.6
  • 42
    • 3943092522 scopus 로고    scopus 로고
    • Javlor enters two new phase III trials in NSCLC and bladder cancer
    • September 15
    • Javlor enters two new phase III trials in NSCLC and bladder cancer. DailyDrugNews.com (Daily Essentials) September 15, 2003.
    • (2003) DailyDrugNews.com (Daily Essentials)
  • 43
    • 3943110201 scopus 로고    scopus 로고
    • Bristol-Myers Squibb receives North American and Asian license for Javlor
    • April 22
    • Bristol-Myers Squibb receives North American and Asian license for Javlor. DailyDrugNews.com (Daily Essentials) April 22, 2004.
    • (2004) DailyDrugNews.com (Daily Essentials)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.