Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study

Toxicology

Volumn 245, Issue 1-2, 2008, Pages 76-89

  Van der Ven, Leo T M ^a   Van de Kuil, Ton ^a   Verhoef, Aart ^a   Verwer, Cynthia M ^b   Lilienthal, Hellmuth ^c   Leonards, Pim E G ^d   Schauer, Ute M D ^e   Cantón, Rocío F ^f   Litens, Sabina ^g   De Jong, Frank H ^h   Visser, Theo J ^h   Dekant, Wolfgang ^e   Stern, Natalia ^g   Håkansson, Helen ^g   Slob, Wout ^a   Van den Berg, Martin ^f   Vos, Josephus G ^a   Piersma, Aldert H ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d INSTITUTE FOR ENVIRONMENTAL STUDIES   (Netherlands)

^e UNIVERSITY OF WÜRZBURG   (Germany)

^f UTRECHT UNIVERSITY   (Netherlands)

^g KAROLINSKA INSTITUTE   (Sweden)

^h ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Development; Endocrine disruption; Hazard identification; Reproduction; Tetrabromobisphenol A; Thyroid hormones

Indexed keywords

AROMATASE; TESTOSTERONE; TETRABROMOBISPHENOL A; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLUSTER ANALYSIS; COGNITION; CORRELATIONAL STUDY; DOSE CALCULATION; DOSE RESPONSE; ENDOCRINOLOGY; ENDOMETRIUM; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GONAD; HORMONE BLOOD LEVEL; HYPOPHYSIS; MALE; MORTALITY; NONHUMAN; ORGAN WEIGHT; OVARY; PRENATAL EXPOSURE; PRIORITY JOURNAL; QUALITY CONTROL; RAT; REPRODUCTION; SEXUAL DEVELOPMENT; TESTIS; TESTOSTERONE BLOOD LEVEL; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DEVELOPMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; FEMALE; MALE; ORGAN SIZE; POLYBROMINATED BIPHENYLS; RATS; RATS, WISTAR; REPRODUCTION; THYROID HORMONES; TISSUE DISTRIBUTION; TOXICITY TESTS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 39249085703     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.12.009     Document Type: Article

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