Left ventricle volume measurements in cardiac micro-CT: The impact of radiation dose and contrast agent

Computerized Medical Imaging and Graphics

Volumn 32, Issue 3, 2008, Pages 239-250

  Badea, Cristian T ^a   Wetzel, Arthur W ^b   Mistry, Nilesh ^a   Pomerantz, Stuart ^b   Nave, Demian ^b   Johnson, G Allan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Cardiac; Micro CT; Phenotyping; Segmentation; Small animal imaging; Volume measurement

Indexed keywords

BINARY MIXTURES; COMPUTERIZED TOMOGRAPHY; CONTRAST MEDIA; DATA STRUCTURES; DATABASE SYSTEMS; DOSIMETRY; VOLUME MEASUREMENT;

CARDIAC CYCLE; CONTRAST AGENT; SMALL ANIMAL IMAGING;

MEDICAL IMAGING;

CONTRAST MEDIUM;

ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; HEART FUNCTION; HEART VENTRICLE VOLUME; IMAGE ANALYSIS; IMAGE QUALITY; IMAGE RECONSTRUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; X RAY;

ANIMALS; CONTRAST MEDIA; HEART VENTRICLES; IMAGING, THREE-DIMENSIONAL; MICE; MICE, INBRED C57BL; RADIATION DOSAGE; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 39249084014     PISSN: 08956111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compmedimag.2007.12.004     Document Type: Article

References (42)

1. James J.F., Hewett T.E., and Robbins J. Cardiac physiology in transgenic mice. Circ Res 82 4 (1998) 407-415
2. Hoit B.D. New approaches to phenotypic analysis in adult mice. J Mol Cell Cardiol 33 (2001) 27-35
3. Camici P.G. Gated PET and ventricular volume. J Nucl Med 44 10 (2003) 1662
4. Hoit B.D., and Walsh R.A. Cardiovascular physiology in the genetically engineered mouse (2001), Kluwer Academic Publishers
5. Slawson S.E., Roman B.B., Williams D.S., and Koretsky A.P. Cardiac MRI of the normal and hypertrophied mouse heart. Magn Res Med 39 (1998) 980-987
6. Franco F., Dubois S.K., Peshock R.M., and Shohet R.V. Magnetic resonance imaging accurately estimates LV mass in a transgenic mouse model of cardiac hypertrophy. Am J Physiol 274 2 Pt 2 (1998) H679-H683
7. Wiesmann F., Ruff J., Hiller K.H., Rommel E., Haase A., and Neubauer S. Developmental changes of cardiac function and mass assessed with MRI in neonatal, juvenile, and adult mice. Am J Physiol Heart Circ Physiol 278 2 (2000) H652-H657
8. Ruff J., Wiesmann F., Hiller K.-H., Voll S., von Kienlin M., Bauer W.R., et al. Magnetic resonance microimaging for noninvasive quantification of myocardial function and mass in the mouse. Magn Res Med 40 (1998) 43-48
9. Brau A.C.S., Hedlund L.W., and Johnson G.A. Cine magnetic resonance microscopy of the rat heart using cardiorespiratory-synchronous projection reconstruction imaging. J Magn Reson Imaging 20 (2004) 31-38
10. Badea C.T., Bucholz E., Hedlund L.W., Rockman H.A., and Johnson G.A. Imaging methods for morphological and functional phenotyping of the rodent heart. Toxicol Pathol 34 1 (2006) 111-117
11. Nahrendorf M., Wiesmann F., Hiller K.H., Hu K., Waller C., Ruff J., et al. Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats. J Magn Reson Imaging 14 5 (2001) 547-555
12. Drangova M., Ford N.L., Detombe S.A., Wheatley A.R., and Holdsworth D.W. Fast retrospectively gated quantitative four-dimensional (4D) cardiac micro computed tomography imaging of free-breathing mice. Invest Radiol 42 2 (2007) 85-94
13. Ford N.L., Thornton M.M., and Holdsworth D.W. Fundamental image quality limits for microcomputed tomography in small animals. Med Phys 30 (2003) 2869-2877
14. Itoh S., Koyama S., Ikeda M., Ozaki M., Sawaki A., Iwano S., et al. Further reduction of radiation dose in helical CT for lung cancer screening using small tube current and a newly designed filter. J Thorac Imaging 16 (2001) 81-88
15. Kachelriess M., Watzke O., and Kalender W.A. Generalized multi-dimensional adaptive filtering for conventional and spiral single-slice, multi-slice, and cone-beam CT. Med Phys 28 (2001) 475-490
16. Donnelly L.F., Emery K.H., Brody A.S., Laor T., Gylys-Morin V.M., Anton C.G., et al. Minimizing radiation dose for pediatric body applications of single-detector helical CT: strategies at a large Children's Hospital. AJR Am J Roentgenol 176 (2001) 303-306
17. Paterson A., Frush D.P., and Donnelly L.F. Helical CT of the body: are settings adjusted for pediatric patients?. AJR Am J Roentgenol 176 (2001) 297-301
18. Kalra M.K., Prasad S., Saini S., Blake M.A., Varghese J., Halpern E.F., et al. Clinical comparison of standard-dose and 50% reduced-dose abdominal CT: effect on image quality. AJR Am J Roentgenol 179 (2002) 1101-1106
19. Kalender W.A., Wolf H., Suess C., Gies M., Greess H., and Bautz W.A. Dose reduction in CT by on-line tube current control: principles and validation on phantoms and cadavers. Eur Radiol 9 (1999) 323-328
20. Greess H., Wolf H., Baum U., Lell M., Pirkl M., Kalender W., et al. Dose reduction in computed tomography by attenuation-based on-line modulation of tube current: evaluation of six anatomical regions. Eur Radiol 10 (2000) 391-394
21. Greess H., Nomayr A., Wolf H., Baum U., Lell M., Bowing B., et al. Dose reduction in CT examination of children by an attenuation-based on-line modulation of tube current (care dose). Eur Radiol 12 (2002) 1571-1576
22. Greess H., Baum U., Wolf H., Lell M., Nomayr A., Schmidt B., et al. Dose reduction in spiral-CT: detection of pulmonary coin lesions with and without anatomically adjusted modulation of tube current. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 173 (2001) 466-470
23. Mastora I., Remy-Jardin M., Suess C., Scherf C., Guillot J.P., and Remy J. Dose reduction in spiral CT angiography of thoracic outlet syndrome by anatomically adapted tube current modulation. Eur Radiol 11 (2001) 590-596
24. Greess H., Wolf H., Baum U., Kalender W.A., and Bautz W. Dosage reduction in computed tomography by anatomy-oriented attenuation-based tube-current modulation: the first clinical results. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 170 (1999) 246-250
25. Lehmann K.J., Wild J., and Georgi M. Clinical use of software-controlled X-ray tube modulation with "Smart-Scan" in spiral CT. Aktuelle Radiol 7 (1997) 156-158
26. Giacomuzzi S.M., Erckert B., Schopf T., Freund M.C., Springer P., Dessl A., et al. The smart-scan procedure of spiral computed tomography. A new method for dose reduction. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 165 (1996) 10-16
27. Otsu N. A threshold selection method for gray level histogram. IEEE Trans Syst Man Cybern (1979) 62-66 SMC-9(1)
28. Haraokawa T, Kido T, Higashino H, Mochizuki T, Shen Y. Accuracy of LV Volume Assessment Using Cardiac MSCT in RSNA. Chicago; 2004.
29. Johnson G., and O'Foghludha F.R. An experimental transmolybdenum tube for mammography. Radiology 127 (1978) 511-516
30. Vera D.R., and Mattrey R.F. A molecular CT blood pool contrast agent. Acad Radiol 9 (2002) 784-792
31. Weichert J.P., Lee F.T.J., Longino M.A., Chosey S.G., and Counsell R.E. Lipid-based blood pool CT imaging of the liver. Acad Radiol 5 (1998) S16-S19
32. Badea C.T., Fubara B., Hedlund L.W., and Johnson G.A. 4-D micro-CT of the mouse heart. Mol Imaging 4 2 (2005) 110-116
33. Badea C.T., Hedlund L.W., and Johnson G.A. Micro-CT with respiratory and cardiac gating. Med Phys 31 12 (2004) 3324-3329
34. Paulus M.J., Gleason S.S., Kennel S.J., Hunsicker P.R., and Johnson D.K. High resolution X-ray computed tomography: an emerging tool for small animal cancer research. Neoplasia 2 1/2 (2000) 62-70
35. Paulus M.J., Gleason S.S., Easterly M.E., and Foltz C.J. A review of high-resolution X-ray computed tomography and other imaging modalities for small animal research. Lab Anim (NY) 30 3 (2001) 36-45
36. Wang G., and Vannier M. Micro-CT scanners for biomedical applications: an overview. Adv Imaging 16 7 (2001) 18-27
37. Hedlund L.W., and Johnson G.A. Mechanical ventilation for imaging the small animal lung. ILAR J 43 3 (2002) 159-174
38. Feldkamp L.A., Davis L.C., and Kress J.W. Practical cone-beam algorithm. J Opt Soc Am 1 6 (1984) 612-619
39. Rose A. The sensitivity performance of the human eye on an absolute scale. J Opt Soc Am 38 (1948) 196-208
40. Mukundan Jr. S., Ghaghada K.B., Badea C.T., Kao C.Y., Hedlund L.W., Provenzale J.M., et al. A liposomal nanoscale contrast agent for preclinical CT in mice. AJR Am J Roentgenol 186 2 (2006) 300-307
41. Gordon R., Bender R., and Herman G.T. Algebraic reconstruction techniques (ART) for three-dimensional electron microscopy and X-ray photography. J Theor Biol 29 (1970) 471-481
42. Guan H., and Gordon R. Computed tomography using algebraic reconstruction techniques (ARTs) with different projection access schemes: a comparison study under practical situations. Phys Med Biol 41 9 (1996) 1727-1743