Listeria monocytogenes desensitizes immune cells to subsequent Ca 2+ signaling via listeriolysin O-induced depletion of intracellular Ca2+ stores

Infection and Immunity

Volumn 76, Issue 2, 2008, Pages 857-862

  Gekara, Nelson O ^a   Groebe, Lothar ^a   Viegas, Nuno ^a   Weiss, Siegfried ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LISTERIOLYSIN O; THAPSIGARGIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; LISTERIA MONOCYTOGENES; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BACTERIAL TOXINS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; HEAT-SHOCK PROTEINS; HEMOLYSIN PROTEINS; LISTERIA MONOCYTOGENES; MAST CELLS; MICE;

EID: 39149112798     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00622-07     Document Type: Article

References (32)

1. Andris, F., M. Van Mechelen, F. De Mattia, E. Baus, J. Urbain, and O. Leo. 1996. Induction of T cell unresponsiveness by anti-CD3 antibodies occurs independently of co-stimulatory functions. Eur. J. Immunol. 26:1187-1195.
2. Ben-Amor, A., M. Leite-De-Moraes, F. Lepault, E. Schneider, F. Machavoine, A. Arnould, L. Chatenoud, and M. Dy. 1995. Role of interleukin-2 receptors in the suppressive effect of spleen cells from anti-CD3-treated mice. Eur. Cytokine Netw. 6:221-224.
3. Berridge, M. J., M. D. Bootman, and H. L. Roderick. 2003. Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol. 4:517-529.
4. Boncristiano, M., S. R. Paccani, S. Barone, C. Ulivieri, L. Patrussi, D. Ilver, A. Amedei, M. M. D'Elios, J. L. Telford, and C. T. Baldari. 2003. The Helicobacter pylori vacuolating toxin inhibits T-cell activation by two independent mechanisms. J. Exp. Med. 198:1887-1897.
5. Carrero, J. A., B. Calderon, and E. R. Unanue. 2004. Listeriolysin O from Listeria monocytogenes is a lymphocyte apoptogenic molecule. J. Immunol. 172:4866-4874.
6. Carrero, J. A., B. Calderon, and E. R. Unanue. 2004. Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. J. Exp. Med. 200:535-540.
7. Darji, A., T. Chakraborty, K. Niebuhr, N. Tsonis, J. Wehland, and S. Weiss. 1995. Hyperexpression of listeriolysin in the nonpathogenic species Listeria innocua and high yield purification. J. Biotechnol. 43:205-212.
8. de Bernard, M., A. Cappon, L. Pancotto, P. Ruggiero, J. Rivera, G. Del Giudice, and C. Montecucco. 2005. The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations. Cell. Microbiol. 7:191-198.
9. Dramsi, S., and P. Cossart. 2003. Listeriolysin O-mediatcd calcium influx potentiates entry of Listeria monocytogenes into the human Hep-2 epithelial cell line. Infect. Immun. 71:3614-3618.
10. Edelson, B. T., Z. Li, L. K. Pappan, and M. M. Zutter. 2004. Mast cell-mediated inflammatory responses require the alpha 2 beta 1 integrin. Blood 103:2214-2220.
11. Edelson, B. T., T. P. Stricker, Z. Li, S. K. Dickeson, V. L. Shepherd, S. A. Santoro, and M. M. Zutter. 2006. Novel collectin/C1q receptor mediates mast cell activation and innate immunity. Blood 107:143-150.
12. Gekara, N. O., T. Jacobs, T. Chakraborty, and S. Weiss. 2005. The cholesterol-dependent cytolysin listeriolysin O aggregates rafts via oligomerization. Cell. Microbiol. 7:1345-1356.
13. Gekara, N. O., and S. Weiss. 2004. Lipid rafts clustering and signalling by listeriolysin O. Biochem. Soc. Trans. 32:712-714.
14. 2+ signalling by listeriolysin O, the cholesterol-dependent cytolysin of Listeria monocytogenes. Cell. Microbiol. 9:2008-2021.
15. Goldfine, H., and S. J. Wadsworth. 2002. Macrophage intracellular signaling induced by Listeria monocytogenes. Microbes Infect. 4:1335-1343.
16. Heissmeyer, V., F. Macian, S. H. Im, R. Varma, S. Feske, K. Venuprasad, H. Gu, Y. C. Liu, M. L. Dustin, and A. Rao. 2004. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat. Immunol. 5:255-265.
17. Heissmeyer, V., F. Macian, R. Varma, S. H. Im, F. Garcia-Cozar, H. F. Horton, M. C. Byrne, S. Feske, K. Venuprasad, H. Gu, Y. C. Liu, M. L. Dustin, and A. Rao. 2005. A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling. Novartis Found. Symp. 267:165-174.
18. Kanner, B. I., and H. Metzger. 1984. Initial characterization of the calcium channel activated by the cross-linking of the receptors for immunoglobulin E. J. Biol. Chem. 259:10188-10193.
19. Macian, F., F. Garcia-Cozar, S. H. Im, H. F. Horton, M. C. Byrne, and A. Rao. 2002. Transcriptional mechanisms underlying lymphocyte tolerance. Cell 109:719-731.
20. Maeyama, K., R. J. Hohman, H. Metzger, and M. A. Beaven. 1986. Quantitative relationships between aggregation of IgE receptors, generation of intracellular signals, and histamine secretion in rat basophilic leukemia (2H3) cells. Enhanced responses with heavy water. J. Biol. Chem. 261:2583-2592.
21. Nishibori, T., H. Xiong, I. Kawamura, M. Arakawa, and M. Mitsuyama. 1996. Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells. Infect. Immun. 64:3188-3195.
22. Nomura, T., I. Kawamura, K. Tsuchiya, C. Kohda, H. Baba, Y. Ito, T. Kimoto, I. Watanabe, and M. Mitsuyama. 2002. Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells. Infect. Immun. 70:1049-1055.
23. Otero, A. C., and G. A. Dos Reis. 1994. Functional inactivation of primary T-cells stimulated in vitro in the presence of cyclosporine. Int. J. Immunopharmacol. 16:941-949.
24. Reiter, Y., A. Ciobotariu, J. Jones, B. P. Morgan, and Z. Fishelson. 1995. Complement membrane attack complex, perforin, and bacterial exotoxins induce in K562 cells calcium-dependent cross-protection from lysis. J. Immunol. 155:2203-2210.
25. 2+ oscillations. Cell. Microbiol. 4:483-491.
26. Rose, F., S.-A. Zeller, T. Chakraborty, E. Domann, T. Machleidt, M. Kronke, W. Seeger, F. Grimminger, and U. Sibelius. 2001. Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors. Infect. Immun. 69:897-905.
27. Shaugbnessy, L. M., A. D. Hoppe, K. A. Christensen, and J. A. Swanson. 2006. Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles. Cell. Microbiol. 8:781-792.
28. Sundrud, M. S., V. J. Torres, D. Unutmaz, and T. L. Cover. 2004. Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc. Natl. Acad. Sci. USA 101:7727-7732.
29. Tsuchiya, K., I. Kawamura, A. Takahashi, T. Nomura, C. Kohda, and M. Mitsuyama. 2005. Listeriolysin O-induced membrane permeation mediates persistent interleukin-6 production in Caco-2 cells during Listeria monocytogenes infection in vitro. Infect. Immun. 73:3869-3877.
30. Tsukada, H., I. Kawamura, T. Fujimura, K. Igarashi, M. Arakawa, and M. Mitsuyama. 1992. Induction of macrophage interleukin-1 production by Listeria monocytogenes hemolysin. Cell. Immunol. 140:21-30.
31. Wadsworth, S. J., and H. Goldfine. 1999. Listeria monocytogenes phospholipase C-dependent calcium signaling modulates bacterial entry into J774 macrophage-like cells. Infect. Immun. 67:1770-1778.
32. Wadsworth, S. J., and H. Goldfine. 2002. Mobilization of protein kinase C in macrophages induced by Listeria monocytogenes affects its internalization and escape from the phagosome. Infect. Immun. 70:4650-4660.