Characterization of hydrogels prepared from copolymerization of the different degrees of methacrylate-grafted chondroitin sulfate macromers and acrylic acid

Journal of Biomedical Materials Research - Part A

Volumn 84, Issue 3, 2008, Pages 727-739

  Tsai, Ming Fung ^a   Tsai, Hung Yu ^a   Peng, Yu Shiang ^a   Wang, Li Fang ^a   Chen, Jenn Shing ^b   Shui, Chun Lu ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL UNIVERSITY OF KAOHSIUNG   (Taiwan)

Author keywords

Chondroitin sulfate; Cytotoxicity; Hydrogels; Methacrylation; Polyacrylic acid

Indexed keywords

ACRYLICS; CHARACTERIZATION; COPOLYMERIZATION; CYTOTOXICITY; GRAFTING (CHEMICAL);

CHONDROITIN SULFATE; METHACRYLATION; POLYACRYLIC ACID;

HYDROGELS;

ACRYLIC ACID; CHONDROITIN SULFATE; ESTERASE; METHACRYLIC ACID; N ACETYLGALACTOSAMINE 4 SULFATASE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROGEL; MESENCHYMAL STEM CELL; PH; POLYMERIZATION; SCANNING ELECTRON MICROSCOPY; SKIN FIBROBLAST; STOMACH JUICE;

ACRYLATES; BIOCOMPATIBLE MATERIALS; CELLS, CULTURED; CHONDROITIN SULFATES; HUMANS; HYDROGELS; MAGNETIC RESONANCE SPECTROSCOPY; METHACRYLATES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 39049170882     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31441     Document Type: Article

References (30)

1. Saylers AA, O'Brien M. Cellular location of enzymes involved in chondroitin sulfate breakdown by Bacteroides thetaiotaomicron. J Bacteriol 1980;143:772-780.
2. Saylers AA, O'Brien, M. Energy sources of major intestinal fermentative anaerobes. Am J Clin Nutr 1979;32:158-163.
3. Sintov A, Di-Capua N, Rubinstein A. Cross-linked chondroitin sulfate: Characterization for drug delivery purposes. Biomaterials 1996;16:473-478.
4. Rubinstein A, Nakar D, Sintov A. Colonic drug delivery: Enhanced release of indomethacin from cross-linked chondroitin matrix in rat cecal content. Pharm Res 1992;9:276-280.
5. Zhao X. Synthesis and characterization of a novel hyaluronic acid hydrogel. J Biomater Sci Polym Ed 2006;17:419-433.
6. Cui CY, Lu WL, Xiao L, Zhang SQ, Huang YB, Li SL, Zhang RJ, Wang GL, Zhang X, Zhang Q. Sublingual delivery of insulin: Effects of enhancers on the mucosal lipid fluidity and protein conformation, transport, and in vivo hypoglycemic activity. Biol Pharm Bull 2005;28:2279-2288.
7. Sajeesh S, Sharma CP. Novel pH responsive polymethacrylic acid-chitosan-polyethylene glycol nanoparticles for oral peptide delivery. J Biomed Mater Res B Appl Biomater 2006;76:298-305.
8. Wang LF, Wang JM. Insolubilization of sodium chondroitin sulfate by forming a semi-interpenetrating polymer network with acrylic acid: A potential carrier for colon-specific drug delivery. J Appl Polym Sci 2002;85:114-128.
9. Wang LF, Shen SS, Lu SC. Synthesis and characterization of chondroitin sulfate-methacrylate hydrogels. Carbohydr Polym 2003;52:389-396.
10. Cadee JA, de Groot CJ, Jiskoot W, den Otter W, Hennink WE. Release of recombinant human interleukin-2 from dextran-based hydrogels. J Control Release 2002;78:1-13.
11. Jiang H, Fang D, Hsiao BS, Chu B, Chen W. Optimization and characterization of dextran membranes prepared by electrospinning. Biomacromolecules 2004;5:326-333.
12. Chiu HC, Lin YF, Hsu YH. Effects of acrylic acid on preparation and swelling properties of pH-sensitive dextran hydrogels. Biomaterials 2002;23:1103-1112.
13. De Groot CJ, Van Luyn MJ, Van Dijk-Wolthuis WN, Cadee JA, Plantinga JA, Den Otter W, Hennink WE. In vitro biocompatibility of biodegradable dextran-based hydrogels tested with human fibroblasts. Biomaterials 2001;22:1197-1203.
14. Leach JB, Schmidt CE. Characterization of protein release from photocrosslinkable hyaluronic acid-polyethylene glycol hydrogel tissue engineering scaffolds. Biomaterials 2005;26:125-135.
15. Cai S, Liu Y, Zheng Shu X, Prestwich GD. Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor. Biomaterials 2005;26:6054-6067.
16. Shu XZ, Ghosh K, Liu Y, Palumbo FS, Luo Y, Clark RA, Prestwich GD. Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel. J Biomed Mater Res A 2004;68:365-376.
17. Pitt WG, Morris RN, Mason ML, Hall MW, Luo Y, Prestwich GD. Attachment of hyaluronan to metallic surfaces. J Biomed Mater Res A 2004;68:95-106.
18. Verestiuc L, Ivanov C, Barbu E, Tsibouklis J. Dual-stimuli-responsive hydrogels based on poly(N-isopropylacrylamide)/chitosan semi-interpenetrating networks. Int J Pharm 2004;269:185-194.
19. Hussain LA, Dickens SH, Bowen RL. Effects of polymerization initiator complexation in methacrylated β-cyclodextrin formulations. Dent Mater 2004;20:513-521.
20. Van den Mooter G, Vervoort L, Kinget R. Characterization of methacrylated inulin hydrogels designed for colon targeting: In vitro release of BSA. Pharm Res 2003;20:303-307.
21. Berger J, Reist M, Mayer JM, Felt O, Gurny R. Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. Eur J Pharm Biopharm 2004;57:35-52.
22. Zhang X, Wu D, Chu CC. Synthesis and characterization of partially biodegradable, temperature and pH sensitive DexMA/PNIPAAm hydrogels. Biomaterials 2004;25:4719-4730.
23. Xue W, Champ S, Huglin MB. Network and swelling parameters of chemically crosslinked thermoreversible hydrogels. Polymer 2001;42:3665-3669.
24. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
25. De Smedt SC, Lauwers A, Demeester J, Van Steenbergen MJ, Hennink WE, Roefs SPFM. Characterization of the network structure of dextran glycidyl methacrylate hydrogels by studying the rheological and swelling behavior. Macromolecules 1995;28:5082-5088.
26. Peppas NA, Merrill EW. Crosslinked poly(vinyl alcohol) hydrogels as swollen elastic networks. J Appl Polym Sci 1977;21:1763-1770.
27. Dawlee S, Sugandhi A, Balakrishnan B, Labarre D, Jayakrishnan A. Oxidized chondroitin sulfate-cross-linked gelatin matrixes: A new class of hydrogels. Biomacromolecules 2005;6:2040-2048.
28. Bryant SJ, Chowdhury TT, Lee DA, Bader DL, Anseth KS. Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels. Ann Biomed Eng 2004;32:407-417.
29. Franssen O, Vandervennet L, Roders P, Hennink WE. Degradable dextran hydrogels: Controlled release of a model protein from cylinders and microspheres. J Control Release 1999;60:211-221.
30. Xing R, Liu S, Yu H, Zhang Q, Li Z, Li P. Preparation of low-molecular-weight and high-sulfate-content chitosans under microwave radiation and their potential antioxidant activity in vitro. Carbohydr Res 2004;339:2515-2519.