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Volumn 72, Issue 5-6, 2008, Pages 279-284

Irinotecan plus gemcitabine and 5-fluorouracil in advanced pancreatic cancer: A phase II study

Author keywords

5 Fluorouracil; Chemotherapy; Gemcitabine; Irinotecan; Pancreatic cancer

Indexed keywords

FLUOROURACIL; GEMCITABINE; IRINOTECAN; OXALIPLATIN; RAPAMYCIN;

EID: 39049169917     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000113039     Document Type: Article
Times cited : (10)

References (21)
  • 2
    • 0019208060 scopus 로고
    • Chemotherapy in pancreatic cancer: Results of a controlled, prospective, randomised, multicentre trial
    • Mallinson CN, Rake MO, Cocking JB, et al: Chemotherapy in pancreatic cancer: results of a controlled, prospective, randomised, multicentre trial. Br Med J 1980;281:1589-1591.
    • (1980) Br Med J , vol.281 , pp. 1589-1591
    • Mallinson, C.N.1    Rake, M.O.2    Cocking, J.B.3
  • 3
    • 0028291349 scopus 로고
    • Chemotherapy prolongs survival in inoperable pancreatic carcinoma
    • Palmer KR, Kerr M, Knowles G, et al: Chemotherapy prolongs survival in inoperable pancreatic carcinoma. Br J Surg 1994;81:882-885.
    • (1994) Br J Surg , vol.81 , pp. 882-885
    • Palmer, K.R.1    Kerr, M.2    Knowles, G.3
  • 4
    • 0029816590 scopus 로고    scopus 로고
    • Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
    • Glimelius B, Hoffman K, Sjoden PO, et al: Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol 1996;7:593-600.
    • (1996) Ann Oncol , vol.7 , pp. 593-600
    • Glimelius, B.1    Hoffman, K.2    Sjoden, P.O.3
  • 5
    • 0345802806 scopus 로고    scopus 로고
    • Review article: Chemotherapy for pancreatic cancer
    • Shore S, Raraty MGT, Ghaneh P, et al: Review article: chemotherapy for pancreatic cancer. Aliment Pharmacol Ther 2003;18:1049-1069.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 1049-1069
    • Shore, S.1    Raraty, M.G.T.2    Ghaneh, P.3
  • 6
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 7
    • 0036498787 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine induces both radiographic and CA19-9 tumor marker responses in patients with previously untreated advanced pancreatic cancer
    • Rocha Lima CM, Savarese D, Bruckner H, et al: Irinotecan plus gemcitabine induces both radiographic and CA19-9 tumor marker responses in patients with previously untreated advanced pancreatic cancer J Clin Oncol 2002;20:1182-1191.
    • (2002) J Clin Oncol , vol.20 , pp. 1182-1191
    • Rocha Lima, C.M.1    Savarese, D.2    Bruckner, H.3
  • 8
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha Lima CM, Green MR, Rotche R, et al: Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 2004;22:3776-3786.
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3786
    • Rocha Lima, C.M.1    Green, M.R.2    Rotche, R.3
  • 9
    • 33645033691 scopus 로고    scopus 로고
    • Phase I-II trial of weekly gemcitabine plus high-dose 5-fluorouracil and leucovorin in advanced pancreatic cancer
    • Shiah HS, Cheng AL, Hsu C, et al: Phase I-II trial of weekly gemcitabine plus high-dose 5-fluorouracil and leucovorin in advanced pancreatic cancer. J Gastroenterol Hepatol 2006;21:531-536.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 531-536
    • Shiah, H.S.1    Cheng, A.L.2    Hsu, C.3
  • 10
    • 0033368083 scopus 로고    scopus 로고
    • Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines
    • Bahadori HR, Rocha Lima CM, Green MR, et al: Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines. Anticancer Res 1999;19:5423-5428.
    • (1999) Anticancer Res , vol.19 , pp. 5423-5428
    • Bahadori, H.R.1    Rocha Lima, C.M.2    Green, M.R.3
  • 11
    • 39049137214 scopus 로고    scopus 로고
    • A phase I study of irinotecan (I), gemcitabine (G), and 5-fluorouracil (5-FU) in patients with advanced gastrointestinal cancers
    • Schlottmann K, Friedrich A, Messmann H, et al: A phase I study of irinotecan (I), gemcitabine (G), and 5-fluorouracil (5-FU) in patients with advanced gastrointestinal cancers. Eur J Cancer 2001;37(suppl 6):A1066.
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 6
    • Schlottmann, K.1    Friedrich, A.2    Messmann, H.3
  • 12
    • 0019365237 scopus 로고
    • Reporting results of cancer treatment
    • Miller AB, Hoogstraten B, Staquet M, et al: Reporting results of cancer treatment. Cancer 1981;47:207-214.
    • (1981) Cancer , vol.47 , pp. 207-214
    • Miller, A.B.1    Hoogstraten, B.2    Staquet, M.3
  • 13
    • 2342645506 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
    • Van Cutsem E, van de Velde H, Karasek P, et al: Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer. J Clin Oncol 2004;22:1430-1438.
    • (2004) J Clin Oncol , vol.22 , pp. 1430-1438
    • Van Cutsem, E.1    van de Velde, H.2    Karasek, P.3
  • 14
    • 0141688333 scopus 로고    scopus 로고
    • Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Hamm J, Dancey J, et al: Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003;21:3296-3302.
    • (2003) J Clin Oncol , vol.21 , pp. 3296-3302
    • Moore, M.J.1    Hamm, J.2    Dancey, J.3
  • 15
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
    • Bramhall SR, Schulz J, Nemunaitis J, et al: A double-blind placebo controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer. Br J Cancer 2002;87:161-167.
    • (2002) Br J Cancer , vol.87 , pp. 161-167
    • Bramhall, S.R.1    Schulz, J.2    Nemunaitis, J.3
  • 16
    • 33745629366 scopus 로고    scopus 로고
    • Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: Results of a phase II randomized, double-blind, placebo-controlled, multicenter study
    • Richards DA, Boehm KA, Waterhouse DM, et al: Gemcitabine plus CI-994 offers no advantage over gemcitabine alone in the treatment of patients with advanced pancreatic cancer: results of a phase II randomized, double-blind, placebo-controlled, multicenter study. Ann Oncol 2006;17:1096-1102.
    • (2006) Ann Oncol , vol.17 , pp. 1096-1102
    • Richards, D.A.1    Boehm, K.A.2    Waterhouse, D.M.3
  • 17
    • 34948888231 scopus 로고    scopus 로고
    • Increased survival using platinum analog combined with gemcitabine as compared to single agent gemcitabine in advanced pancreatic cancer: Pooled analysis of two randomized trials, the GERCOR/GISCAD Intergroup Study and a German multicenter study
    • Heinemann V, Labianca R, Hinke A, Louvet C: Increased survival using platinum analog combined with gemcitabine as compared to single agent gemcitabine in advanced pancreatic cancer: pooled analysis of two randomized trials, the GERCOR/GISCAD Intergroup Study and a German multicenter study. Ann Oncol 2007;18:1652-1659.
    • (2007) Ann Oncol , vol.18 , pp. 1652-1659
    • Heinemann, V.1    Labianca, R.2    Hinke, A.3    Louvet, C.4
  • 18
    • 0033559213 scopus 로고    scopus 로고
    • An investigational new drug treatment program for patients with gemcitabine
    • Storniolo AM, Enas MH, Brown CA, et al: An investigational new drug treatment program for patients with gemcitabine. Cancer 1999;85:1261-1268.
    • (1999) Cancer , vol.85 , pp. 1261-1268
    • Storniolo, A.M.1    Enas, M.H.2    Brown, C.A.3
  • 19
    • 33748297529 scopus 로고    scopus 로고
    • A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer
    • Stathopoulos GP, Syrigos K, Aravantinos G, et al: A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer. Br J Cancer 2006;95:587-592.
    • (2006) Br J Cancer , vol.95 , pp. 587-592
    • Stathopoulos, G.P.1    Syrigos, K.2    Aravantinos, G.3
  • 20
    • 33749071359 scopus 로고    scopus 로고
    • Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer
    • Abou-Alfa GK, Letourneau R, Harker G, et al: Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. J Clin Oncol 2006;24:4441-4447.
    • (2006) J Clin Oncol , vol.24 , pp. 4441-4447
    • Abou-Alfa, G.K.1    Letourneau, R.2    Harker, G.3
  • 21
    • 29344476191 scopus 로고    scopus 로고
    • Phase III randomized comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer
    • Cunningham D, Chau I, Stocken D, et al: Phase III randomized comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer. Eur J Cancer 2005;3(suppl 4):PS11.
    • (2005) Eur J Cancer , vol.3 , Issue.SUPPL. 4
    • Cunningham, D.1    Chau, I.2    Stocken, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.