Structural analysis of sialyltransferase PM0188 from Pasteurella multocida complexed with donor analogue and acceptor sugar

Journal of Biochemistry and Molecular Biology

Volumn 41, Issue 1, 2008, Pages 48-54

  Kim, Dong Uk ^a   Yoo, Ji Ho ^a   Yong, Joo Lee ^a   Kwan, Soo Kim ^a   Cho, Hyun Soo ^a  

^a Yonsei University   (South Korea)

Author keywords

CMP 3FNeuAc; CMP NeuAc; Lactose; PM0188; Sialyltransferase; X ray crystallography

Indexed keywords

PASTEURELLA MULTOCIDA;

EID: 39049156730     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2008.41.1.048     Document Type: Article

References (20)

1. Campbell, J. A., Davies, G. J., Bulone, V. and Henrissat, B. (1997) A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities. Biochem. J. 326, 929-939.
2. Yu, H., Chokhawala, H., Karpel, R., Yu, H., Wu, B., Zhang, J., Zhang, Y., Jia, Q. and Chen, X. (2005) A multifunctional Pasteurella multocida sialyltransferase: a powerful tool for the synthesis of sialoside libraries. J. Am. Chem. Soc. 127, 17618-17619.
3. Cooke, F. J., Kodjo, A., Clutterbuck, E. J. and Bamford, K. B. (2004) A case of Pasteurella multocida peritoneal dialysis-associated peritonitis and review of the literature. Int. J. Infect. Dis. 8, 171-174.
4. Harduin-Lepers, A., Vallejo-Ruiz, V., Krzewinski-Recchi, M. A., Samyn-Petit, B., Julien, S. and Delannoy, P. (2001) The human sialyltransferase family. Biochimie 83, 727-737.
5. Rudd, P. M., Elliott, T., Cresswell, P., Wilson, I. A. and Dwek, R. A. (2001) Glycosylation and the immune system. Science 291, 2370-2376.
6. Ni, L., Chokhawala, H. A., Cao, H., Henning, R., Ng, L., Huang, S., Yu, H., Chen, X. and Fisher, A. J. (2007) Crystal structures of Pasteurella multocida sialyltransferase complexes with acceptor and donor analogues reveal substrate binding sites and catalytic mechanism. Biochemistry 46, 6288-6298.
7. Ni, L., Sun, M., Yu, H., Chokhawala, H., Chen, X. and Fisher, A. J. (2006) Cytidine 5′-monophosphate (CMP)-induced structural changes in a multifunctional sialyltransferase from Pasteurella multocida. Biochemistry 45, 2139-2148.
8. Unligil, U. M. and Rini, J. M. (2000) Glycosyltransferase structure and mechanism. Curr. Opin. Struct. Biol. 10, 510-517.
9. Pedersen, L. C., Darden, T. A. and Negishi, M. (2002) Crystal structure of beta 1,3-glucuronyltransferase I in complex with active donor substrate UDP-GlcUA. J. Biol. Chem. 277, 21869-21873.
10. Pedersen, L. C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J. M., Pedersen, L. G., Sugahara, K. and Negishi, M. (2003) Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis. J. Biol. Chem. 278, 14420-14428.
11. Crennell, S., Takimoto, T., Portner, A. and Taylor, G. (2000) Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase. Nat. Struct. Biol. 7, 1068-1074.
12. Burmeister, W. P., Henrissat, B., Bosso, C., Cusack, S. and Ruigrok, R. W. (1993) Influenza B virus neuraminidase can synthesize its own inhibitor. Structure 1, 19-6.
13. Carugo, O. and Argos, P. (1997) NADP-dependent enzymes. I: conserved stereochemistry of cofactor binding. Proteins 28, 10-28.
14. Kim, D. U., Yoo, J. H., Ryu, K. and Cho, H. S. (2006) Crystallization and preliminary X-ray crystallographic analysis of the alpha-2,6-sialyltransferase PM0188 from Pasteurella multosida. Acta crystallogr. F Struct. Biol. Cryst. Commun. 62, 142-144.
15. Otwinowski, Z. and Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326.
16. Jones, T. A., Zou, J. Y., Cowan, S. W. and Kjeldgaard, M. (1991) Improved methods for building protein models in electron density maps and the location of errors in the model. Acta Crystallogr. A 47, 110-119.
17. Brunger, A. T., Adams, P. D., Clore, G. M., De Lano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T. and Warren, G. L. (1998) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905-921.
18. Vaguine, A. A., Richelle, J. and Wodak, S. J. (1999) SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model. Acta Crystallogr. D Biol. Crystallogr. 55, 191-205.
19. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K. and Pease, L. R. (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59.
20. Gosselin, S., Alhussaini, M., Streiff, M. B., Takabayashi, K. and Palcic, M. M. (1994) A continuous spectrophotometric assay for glycosyltransferases. Anal. Biochem. 220, 92-97.