Inactivation of the Mycobacterium tuberculosis fadB4 gene results in increased virulence in host cell and mice

Microbes and Infection

Volumn 10, Issue 1, 2008, Pages 38-44

  Scandurra, G M ^a   Britton, W J ^a   Triccas, J A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

fadB4; Gene deletion; Macrophage; Mycobacterium tuberculosis; Quinone oxidoreductase; Virulence

Indexed keywords

BACTERIAL PROTEIN; PROTEIN FADB 4; RAG1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE DISRUPTION; GENE INACTIVATION; HOST CELL; IN VIVO STUDY; INFECTION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; VIRULENCE; WILD TYPE;

ANIMALS; BACTERIAL PROTEINS; CELL LINE; COLONY-FORMING UNITS ASSAY; FEMALE; GENE DELETION; GENETIC COMPLEMENTATION TEST; HOMEODOMAIN PROTEINS; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS, INSERTIONAL; MYCOBACTERIUM TUBERCULOSIS; SURVIVAL ANALYSIS; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 39049133433     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.10.001     Document Type: Article

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