Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

Microbes and Infection

Volumn 8, Issue 8, 2006, Pages 2245-2253

  Stadthagen, Gustavo ^a   Jackson, Mary ^a   Charles, Patricia ^a   Boudou, Frédéric ^a   Barilone, Nathalie ^a   Huerre, Michel ^a   Constant, Patricia ^d   Liav, Avraham ^e   Bottova, Iveta ^a   Nigou, Jérôme ^d   Brando, Thérèse ^d   Puzo, Germain ^d   Daffé, Mamadou ^d   Benjamin, Pearline ^c   Coade, Stephen ^c   Buxton, Roger S ^c   Tascon, Ricardo E ^c   Rae, Aaron ^b   Robertson, Brian D ^b   Lowrie, Douglas B ^c   Young, Douglas B ^b   Gicquel, Brigitte ^a   Griffin, Ruth ^b   more..

^a INSTITUT PASTEUR   (France)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^e Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Mycobacterium; p Hydroxybenzoic acid derivatives; Phenolic glycolipids; Tuberculosis

Indexed keywords

4 HYDROXYBENZOIC ACID; GLYCOCONJUGATE; HYDROXYBENZOIC ACID DERIVATIVE; INTERLEUKIN 12; INTERLEUKIN 6; PHENOLIC GLYCOLIPID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM ISOLATE; BACTERIUM MUTANT; BIOSYNTHESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; FEMALE; LUNG INJURY; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENICITY; PNEUMONIA; PRIORITY JOURNAL; TRANSPOSON; TUBERCULOSIS;

BACILLI (CLASS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 33748209096     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.04.008     Document Type: Article

References (30)

1. Manca C., Tsenova L., Barry III C.E., Bergtold A., Freeman S., Haslett P.A.J., Musser J.M., Freedman V.H., and Kaplan G. Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vivo, but is not more virulent than other clinical isolates. J. Immunol. 162 (1999) 6740-6746
2. Rousseau C., Winter N., Pivert E., Bordat Y., Neyrolles O., Avé P., Huerre M., Gicquel B., and Jackson M. Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection. Cell. Microbiol. 6 (2004) 277-287
3. Reed M.B., Domenech P., Manca C., Su H., Barczak A.K., Kreiswirth B.N., Kaplan G., and Barry III C.E. A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 431 (2004) 84-87
4. Rao V., Fujiwara N., Porcelli S.A., and Glickman M.S. Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J. Exp. Med. 201 (2005) 535-543
5. Tailleux L., Maeda N., Nigou J., Gicquel B., and Neyrolles I. How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis. Trends Microbiol. 11 (2003) 259-263
6. Gatfield J., and Pieters J. Molecular mechanisms of host-pathogen interaction: entry and survival of mycobacteria in macrophages. Adv. Immunol. 81 (2003) 45-96
7. Quesniaux V., Fremond C., Jacobs M., Parida S., Nicolle D., Yeremeev V., Bihl F., Erard F., Botha T., Drennan M., Soler M.-N., Le Bert M., Schnyder B., and Ryffel B. Toll-like receptor pathways in the immune responses to mycobacteria. Microbes Infect. 6 (2004) 946-959
8. Briken V., Porcelli S.A., Besra G.S., and Kremer L. Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response. Mol. Microbiol. 53 (2004) 391-403
9. Brennan P.J. Microbial Lipids. In: Ratledge C., and Wilkinson S.G. (Eds) (1988), Academic Press Ltd, London 203-298
10. Puzo G. The carbohydrate- and lipid-containing cell wall of mycobacteria, phenolic glycolipids: structure and immunological properties. Critic. Rev. Microbiol. 17 (1990) 305-327
11. Constant P., Pérez E., Malaga W., Lanéelle M.-A., Saurel O., Daffé M., and Guilhot C. Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. J. Biol. Chem. 277 (2002) 38148-38158
12. Vachula M., Holzer T.J., and Andersen B.R. Suppression of monocyte oxidative response by phenolic glycolipid I of Mycobacterium leprae. J. Immunol. 60 (1989) 203-206
13. Launois P., Blum L., Dieye A., Millan J., Sarthou J.L., and Bach M.A. Phenolic glycolipid-I from M. leprae inhibits oxygen free radical production by human mononuclear cells. Res. Immunol. 140 (1989) 847-855
14. Vachula M., Holzer T.J., Kizlaitis L., and Andersen B.R. Effect of Mycobacterium leprae's phenolic glycolipid-I on interferon-gamma augmentation of monocyte oxidative responses. Int. J. Lepr. Other Mycobact. Dis. 58 (1990) 342-346
15. Silva C.L., Faccioli L.H., and Foss N.T. Suppression of human monocyte cytokine release by phenolic glycolipid-I of Mycobacterium leprae. Int. J. Lepr. Other Mycob. Dis. 61 (1993) 107-108
16. Charlab R., Sarno E.N., Chatterjee D., and Pessolani M.C. Effect of unique Mycobacterium leprae phenolic glycolipid-I (PGL-I) on tumour necrosis factor production by human mononuclear cells. Lepr. Rev. 72 (2001) 63-69
17. Tsenova L., Ellison E., Harbacheuski R., Moreira A.L., Kurepina N., Reed M.B., Mathema B., Barry III C.E., and Kaplan G. Virulence of selected Mycobacterium tuberculosis clinical isolates in the rabbit model of meningitis is dependent on phenolic glycolipid produced by the bacilli. J. Infect. Dis. 192 (2005) 98-106
18. Jackson M., Raynaud C., Lanéelle M.-A., Guilhot C., Laurent-Winter C., Ensergueix D., Gicquel B., and Daffé M. Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope. Mol. Microbiol. 31 (1999) 1573-1587
19. Hunter S.W., Gaylord H., and Brennan P.J. Structure and antigenicity of the phosphorylated lipopolysaccharide antigens from the leprosy and tubercle bacilli. J. Biol. Chem. 261 (1986) 12345-12351
20. Prod'hom G., Lagier B., Pelicic V., Hance A.J., Gicquel B., and Guilhot C. A reliable amplification technique for the characterization of genomic DNA sequences flanking insertion sequences. FEMS Microbiol. Lett. 158 (1998) 75-81
21. Stadthagen G., Korduláková J., Griffin R., Constant P., Bottová I., Barilone N., Gicquel B., Daffé M., and Jackson M. p-hydroxybenzoic acid synthesis in Mycobacterium tuberculosis. J. Biol. Chem. 280 (2005) 40699-40706
22. Nigou J., Gilleron M., Brando T., and Puzo G. Structural analysis of mycobacterial lipoglycans. Appl. Biochem. Biotechnol. 118 (2004) 253-267
23. Jackson M., Phalen S.W., Lagranderie M., Ensergueix D., Chavarot P., Marchal G., McMurray D.N., Gicquel B., and Guilhot C. Persistence and protective efficacy of a Mycobacterium tuberculosis auxotroph vaccine. Infect. Immun. 67 (1999) 2867-2873
24. Pérez E., Constant P., Lemassu A., Laval F., Daffé M., and Guilhot C. Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex. J. Biol. Chem. 279 (2004) 42574-42583
25. Pérez E., Constant P., Laval F., Lemassu A., Lanéelle M.-A., Daffé M., and Guilhot C. Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycocerosate in the Mycobacterium tuberculosis complex. J. Biol. Chem. 279 (2004) 42584-42592
26. Orme I.M. Immunity to Mycobacterium. R.G. Landes Company (1995), Texas, U.S.A.
27. Flynn J.L., and Chan J. Immunology of tuberculosis. Annu. Rev. Immunol. 19 (2001) 93-129
28. Kaufmann S.H. How can immunology contribute to the control of tuberculosis?. Nat. Rev. Immunol. 1 (2001) 20-30
29. Flynn J.L., and Chan J. Immune evasion by Mycobacterium tuberculosis: living with the enemy. Curr. Opin. Immunol. 15 (2003) 450-455
30. Hisert K.B., Kirksey M.A., Gomez J.E., Sousa A.O., Cox J.S., Jacobs Jr. W.R., Nathan C.F., and McKinney J.D. Identification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screening. Infect. Immun. 72 (2004) 5315-5321