Characterization of a cidofovir-resistant HHV-6 mutant obtained by in vitro selection

Antiviral Research

Volumn 77, Issue 3, 2008, Pages 237-240

  Bonnafous, Pascale ^a   Boutolleau, David ^a   Naesens, Lieve ^b   Deback, Claire ^a   Gautheret Dejean, Agnès ^a,c   Agut, Henri ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

Cidofovir; DNA polymerase; HHV 6; Resistance

Indexed keywords

AMINO ACID; CIDOFOVIR; DNA POLYMERASE; FOSCARNET; GANCICLOVIR; VIRUS DNA;

ANTIVIRAL RESISTANCE; ARTICLE; DRUG SENSITIVITY; GENE INTERACTION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; IC 50; IN VITRO SELECTION; NONHUMAN; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIVIRAL AGENTS; CYTOSINE; DNA MUTATIONAL ANALYSIS; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; HERPESVIRUS 6, HUMAN; INHIBITORY CONCENTRATION 50; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHOSPHONIC ACIDS; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 6;

EID: 39049125459     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.12.004     Document Type: Article

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