-
1
-
-
42549091815
-
-
American Cancer Society. Cancer Facts and figures 2005 [on-fine] Available from: URL: www.cancer.org/downloads/STT/CAFF2005f4PWSecured.pdf
-
American Cancer Society. Cancer Facts and figures 2005 [on-fine] Available from: URL: www.cancer.org/downloads/STT/CAFF2005f4PWSecured.pdf
-
-
-
-
2
-
-
0027532535
-
Cytotoxic chemotherapy for advanced hormone-refractory prostate cancer
-
Yagoda A, Petrylak D. Cytotoxic chemotherapy for advanced hormone-refractory prostate cancer. Cancer 1993;71:1098-109
-
(1993)
Cancer
, vol.71
, pp. 1098-1109
-
-
Yagoda, A.1
Petrylak, D.2
-
3
-
-
4744366279
-
Docecaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, De Wit R, Berry WR, et al. Docecaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004;351(15):1502-12
-
(2004)
N Engl J Med
, vol.351
, Issue.15
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
-
4
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxancrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tingen CM, Hussain MHA, et al. Docetaxel and estramustine compared with mitoxancrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004;351:1513-20
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tingen, C.M.2
Hussain, M.H.A.3
-
5
-
-
0026100365
-
Potential antimmor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthenone-4-acetic acids
-
Rewcastle GW, Atwell GJ, Zhuang L, Baguley BC, Denny WA. Potential antimmor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthenone-4-acetic acids. J Med Chem 1991;34:217-20
-
(1991)
J Med Chem
, vol.34
, pp. 217-220
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Zhuang, L.3
Baguley, B.C.4
Denny, W.A.5
-
6
-
-
1642352048
-
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice
-
Ching L-M, Zwain S, Baguley BC. Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice. Br J Cancer 2004;90:906-10
-
(2004)
Br J Cancer
, vol.90
, pp. 906-910
-
-
Ching, L.-M.1
Zwain, S.2
Baguley, B.C.3
-
7
-
-
0037125028
-
Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
-
Ching L-M, Cao Z, Kieda C, et al. Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Br J Cancer 2002;86:1937-42
-
(2002)
Br J Cancer
, vol.86
, pp. 1937-1942
-
-
Ching, L.-M.1
Cao, Z.2
Kieda, C.3
-
8
-
-
22044437369
-
Mechanisms of tumor vascular shutdown induced by 5,6-Dimethylxanthenone-4-acetic acid (DMXAA): Increased tumor vascular permeability
-
Zhao L, Ching LM, Kestell P, et al. Mechanisms of tumor vascular shutdown induced by 5,6-Dimethylxanthenone-4-acetic acid (DMXAA): increased tumor vascular permeability. Int J Cancer 2005;116:322-6
-
(2005)
Int J Cancer
, vol.116
, pp. 322-326
-
-
Zhao, L.1
Ching, L.M.2
Kestell, P.3
-
9
-
-
0033083206
-
Stimulation of rumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: A novel approach to cancer therapy
-
Joseph WR, Cao Z, Mountjoy KG, et al. Stimulation of rumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: a novel approach to cancer therapy. Cancer Res 1999;59:633-8
-
(1999)
Cancer Res
, vol.59
, pp. 633-638
-
-
Joseph, W.R.1
Cao, Z.2
Mountjoy, K.G.3
-
10
-
-
18844385964
-
Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy
-
McPhail LD, Chung Y-L, Madhu B, et al. Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy. Clin Cancer Res 2005;11:3705-13
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3705-3713
-
-
McPhail, L.D.1
Chung, Y.-L.2
Madhu, B.3
-
11
-
-
0037726779
-
NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Woon S-T, Zwain S, Schooltink MA et al. NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Eur J Cancer 2003;39:1176-83
-
(2003)
Eur J Cancer
, vol.39
, pp. 1176-1183
-
-
Woon, S.-T.1
Zwain, S.2
Schooltink, M.A.3
-
12
-
-
33847648543
-
NF-kappa B-independent induction of endothelial cell apoptosis by the vascular disrupting agent DMXAA
-
Woon ST Hung SSC, Wu DCF, et al. NF-kappa B-independent induction of endothelial cell apoptosis by the vascular disrupting agent DMXAA. Anticancer Res 2007;27:327-34
-
(2007)
Anticancer Res
, vol.27
, pp. 327-334
-
-
Woon ST Hung, S.S.C.1
Wu, D.C.F.2
-
13
-
-
34248653457
-
Evidence for the involvement of p38 MAP kinase in the action of the vascular disupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Zhao L, Marshall ES, Kelland LR, Baguley BC. Evidence for the involvement of p38 MAP kinase in the action of the vascular disupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Invest New Drugs 2007;25:271-6
-
(2007)
Invest New Drugs
, vol.25
, pp. 271-276
-
-
Zhao, L.1
Marshall, E.S.2
Kelland, L.R.3
Baguley, B.C.4
-
14
-
-
34547125116
-
The vascular disrupting ageqt, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumour cytotoxic T lymphocytes
-
Wallace A, Larosa DF, Kapoor V, et al. The vascular disrupting ageqt, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumour cytotoxic T lymphocytes. Cancer Res 2007;67:7011-19
-
(2007)
Cancer Res
, vol.67
, pp. 7011-7019
-
-
Wallace, A.1
Larosa, D.F.2
Kapoor, V.3
-
15
-
-
34447330454
-
The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signalling axis
-
Roberts ZJ, Goutagny N, Perea P-Y, et al. The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signalling axis. J Exp Med 2007;204:1559-69
-
(2007)
J Exp Med
, vol.204
, pp. 1559-1569
-
-
Roberts, Z.J.1
Goutagny, N.2
Perea, P.-Y.3
-
16
-
-
0037341637
-
Antivascular therapy of cancer: DMXAA. I-ancet
-
Baguley BC. Antivascular therapy of cancer: DMXAA. I-ancet Oncol 2003;4:141-8
-
(2003)
Oncol
, vol.4
, pp. 141-148
-
-
Baguley, B.C.1
-
18
-
-
0038576231
-
5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: Phase 1 clinical and pharmacokinetic study
-
Rustin GJS, Bradley C, Galbraith S, et al. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: Phase 1 clinical and pharmacokinetic study. Br J Cancer 2003;88:1160-7
-
(2003)
Br J Cancer
, vol.88
, pp. 1160-1167
-
-
Rustin, G.J.S.1
Bradley, C.2
Galbraith, S.3
-
19
-
-
0038575250
-
Clinical aspects of a Phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent
-
Jameson MB, Thompson PI, Baguley BC, et al. Clinical aspects of a Phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent. Br J Cancer 2003;88:1844-50
-
(2003)
Br J Cancer
, vol.88
, pp. 1844-1850
-
-
Jameson, M.B.1
Thompson, P.I.2
Baguley, B.C.3
-
20
-
-
33847157946
-
Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel vascular disrupting agent, in a Phase I clinical trial
-
Jameson MB, Baguley BC, Kestell P, Zhao L, Paxton JW, Thompson PI. Pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel vascular disrupting agent, in a Phase I clinical trial. Cancer Chemother Pharmacol 2007;59:681-7
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 681-687
-
-
Jameson, M.B.1
Baguley, B.C.2
Kestell, P.3
Zhao, L.4
Paxton, J.W.5
Thompson, P.I.6
-
21
-
-
33645659565
-
5,6-Dimethylxanthenone-4-acetic acid (DMXAA) in the treatment of refractory tumors: A Phase I safety study of a vascular disrupting agent
-
McKeage MJ, Fong P, Jeffery M, Baguley BC, Kestell P, Ravic M, Jameson MB. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) in the treatment of refractory tumors: a Phase I safety study of a vascular disrupting agent. Clin Cancer Res 2006;12:1776-84
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1776-1784
-
-
McKeage, M.J.1
Fong, P.2
Jeffery, M.3
Baguley, B.C.4
Kestell, P.5
Ravic, M.6
Jameson, M.B.7
-
22
-
-
0037106501
-
Effects of 5,6-Dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast enhanced magnetic resonance imaging
-
Galbraith SM, Rustin GJS, Lodge MA, et al. Effects of 5,6-Dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast enhanced magnetic resonance imaging. J Clin Oncol 2002;20(18):3826-40
-
(2002)
J Clin Oncol
, vol.20
, Issue.18
, pp. 3826-3840
-
-
Galbraith, S.M.1
Rustin, G.J.S.2
Lodge, M.A.3
-
23
-
-
0037222218
-
Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Sinn BG, Lee AE, Shalal-Zwain S, Pruijn FB, McKeage MJ, Wilson WR. Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Chemother Pharmacol 2003;15:43-52
-
(2003)
Cancer Chemother Pharmacol
, vol.15
, pp. 43-52
-
-
Sinn, B.G.1
Lee, A.E.2
Shalal-Zwain, S.3
Pruijn, F.B.4
McKeage, M.J.5
Wilson, W.R.6
-
24
-
-
18844372057
-
Targeting established tumor vasculature: A novel approach to cancer treatment
-
Kelland LR. Targeting established tumor vasculature: a novel approach to cancer treatment. Cur Cancer Ther Rev 2005;1:1-9
-
(2005)
Cur Cancer Ther Rev
, vol.1
, pp. 1-9
-
-
Kelland, L.R.1
-
25
-
-
33846878300
-
5,6-dimethylxanthenoine-4-acetic acid (DMXAA) clinical potential in combination with taxane-based chemotherapy
-
McKeage MJ, Kelland LR. 5,6-dimethylxanthenoine-4-acetic acid (DMXAA) clinical potential in combination with taxane-based chemotherapy. Am J Cancer 2006;5(3):155-62
-
(2006)
Am J Cancer
, vol.5
, Issue.3
, pp. 155-162
-
-
McKeage, M.J.1
Kelland, L.R.2
-
26
-
-
0031016945
-
Mechanisms of enhancement of the antitumour activity of melphalan by the tumour-blood-flow inhibitor 5,6-dimethylxanthenone-4-acetic acid
-
Pruijn FB, Vandaalen M, Holford NHG, et al. Mechanisms of enhancement of the antitumour activity of melphalan by the tumour-blood-flow inhibitor 5,6-dimethylxanthenone-4-acetic acid. Cancer Chemother Pharmacol 1997;39:541-6.
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 541-546
-
-
Pruijn, F.B.1
Vandaalen, M.2
Holford, N.H.G.3
-
27
-
-
0033034008
-
Clinical pharmacokinetics of docetaxel
-
Clarke SJ, Rivory L. Clinical pharmacokinetics of docetaxel. Clin Pharmacokinet 1999;36:99-114
-
(1999)
Clin Pharmacokinet
, vol.36
, pp. 99-114
-
-
Clarke, S.J.1
Rivory, L.2
-
28
-
-
0031973791
-
The taxoids: Comparative clinical pharmaology and therapeutic potential
-
Eisenhauer EA, Vermorken JB. The taxoids: comparative clinical pharmaology and therapeutic potential. Drugs 1998;55:5-30
-
(1998)
Drugs
, vol.55
, pp. 5-30
-
-
Eisenhauer, E.A.1
Vermorken, J.B.2
-
29
-
-
42549122351
-
Randomised Phase II study in prostate cancer with or owthout DMXAA (AS1404) in hormone refractory metastatic prostate cancer (HRMPC)
-
Abstract 219
-
Rosenthal M, Pili R. Randomised Phase II study in prostate cancer with or owthout DMXAA (AS1404) in hormone refractory metastatic prostate cancer (HRMPC). Proceedings of the American Society for Clinical Oncology, 2007:Abstract 219
-
(2007)
Proceedings of the American Society for Clinical Oncology
-
-
Rosenthal, M.1
Pili, R.2
-
30
-
-
42549110982
-
Phase Ib/II study of DMXAA combined with carboplatin and paclitaxel in non-small cell lung cancer (NSCLC)
-
Abstract 7102
-
McKeage M. Phase Ib/II study of DMXAA combined with carboplatin and paclitaxel in non-small cell lung cancer (NSCLC). Proceedings of the American Society for Clinical Oncology, 2006:Abstract 7102
-
(2006)
Proceedings of the American Society for Clinical Oncology
-
-
McKeage, M.1
|