Modulation of STAT5 interaction with LMW-PTP during early megakaryocyte differentiation

Biochemistry

Volumn 47, Issue 6, 2008, Pages 1482-1489

  Rigacci, Stefania ^a   Guidotti, Valentina ^a   Parri, Matteo ^a   Berti, Andrea ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; PHOSPHORYLATION; PROTEINS;

MEGAKARYOCYTE DIFFERENTIATION; SH2 DOMAINS; STAT5 INTERACTION; THREONINE PHOSPHORYLATION;

CELL PROLIFERATION;

PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN TYROSINE PHOSPHATASE; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

CELL DIFFERENTIATION; CELL LINE; HUMANS; MEGAKARYOCYTES; MOLECULAR WEIGHT; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASES; STAT5 TRANSCRIPTION FACTOR;

EID: 38949194993     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701131e     Document Type: Article

References (34)

1. Paukku, K., and Silvennoinen, O. (2004) STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5, Cytokine Growth Factor Rev. 15, 435-455.
2. Moriggl, R., Gouilleux-Gruart, V., Jäne, R., Berchtold, S., Gartmann, C., Liu, X., Hennighausen, L., Sotiropoulos, A., Gröner, B., and Gouilleux, F. (1996) Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype, Mol. Cell. Biol. 16, 5691-5700.
3. Rigacci, S., Talini, D., and Berti, A (2003) LMW-PTP associates and dephosphorylates STAT5 interacting with its C-terminal domain, Biochem. Biophys. Res. Commun. 312, 360-366.
4. Kieslinger, M., Woldman, I., Moriggl, R., Hofmann, J., Marine, J. C., Ihle, J. N., Beug, H., and Decker, T. (2000) Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation, Genes Dev. 14, 232-244.
5. Dolznig, H., Grebien, F., Deiner, E. M., Stangl, K., Kolbus, A., Habermann, B., and Kerenyi, M. A. (2006) Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR, Oncogene 25, 2890-2900.
6. Jiang, F., Jia, Y., and Cohen, I. (2000) Fibronectin- and protein kinase C-mediated activation of ERK/MAPK are essential for proplateletlike formation, Blood 99, 3579-3584.
7. Avraham, H., and Price, D. J. (1999) Regulation of megakaryocytopoiesis and platelet production by tyrosine kinases and tyrosine phosphatases, Methods 17, 250-264.
8. Liu, R. Y., Fan, C., Garcia, R., Jove, R., and Zuckerman, K. S. (1999) Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines, Blood 93, 2369-2379.
9. Greenberg, S. M., Rosenthal, D. S., Greeley, T. A., Tantravahi, R., and Handin, R. I. (1988) Characterization of a new megakaryocytic cell line: the Dami cell, Blood 72, 1968-1977.
10. Berti, A., Rigacci, S., Raugei, G., Degl'Innocenti, D., and Ramponi, G. (1994) Inhibition of cellular response to platelet-derived growth factor by low M(r) phosphotyrosine protein phosphatase overexpression, FEBS Lett. 349, 7-12.
11. Gowri, P. M., Ganguly, T. C., Cao, J., Devalaraja, M. N., Gröner, B., and Vore, M. (2001) Conversion of threonine 757 to valine enhances Stat5a transactivation potential, J. Biol. Chem. 276, 10485-10491.
12. Ramponi, G., Ruggiero, M., Raugei, G., Berti, A., Modesti, A., Degl'Innocenti, D., Magnelli, L., Pazzagli, C., Chiarugi, V. P., and Camici, G. (1992) Overexpression of a synthetic phosphotyrosine protein phosphatase gene inhibits normal and transformed cell growth, Int. J. Cancer 51, 652-656.
13. Bentley, J. K., Juilfs, D. M., and Uhler, M. D. (2001) Nerve growth factor inhibits PC12 cell PDE2 phosphodiesterase activity and increase PDE2 binding to phosphoproteins, J. Neurochem. 76, 1252-1263.
14. Rigacci, S., Bucciantini, M., Marzocchini, R., and Berti, A. (1998) Low molecular weight phosphotyrosine protein phosphatase translocation during cell stimulation with platelet-derived growth factor, FEBS Lett. 432, 145-149.
15. Piekorz, R. P., Rinke, R., Gouilleux, F., Neumann, B., Gröner, B., and Hocke, G. M (1998) Modulation of the activation status of Stat5a during LIF-induced differentiation of M1 myeloid leukemia cells, Biochim. Biophys. Acta 1402, 313-323.
16. Buitenhuis, M., Baltus, B., Lammers, J. W., Coffer, P. J., and Koenderman, L. (2003) Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells, Blood 101, 134-142.
17. Young, S., Parker, J. P., Ullrich, A., and Stabel, S. (1987) Downregulation of protein kinase C is due to an increased rate of degradation, Biochem. J. 244, 775-779.
18. Rigacci, S., Rovida, E., Dello Sbarba, P., and Berti, A. (2002) Low Mr phosphotyrosine protein phosphatase associates and dephosphorylates p125 focal adhesion kinase, interfering with cell motility and spreading, J. Biol. Chem. 277, 41631-41636.
19. Yao, Z., Cui, Y., Watford, W. T., Bream, J. H., Yamaoka, K., Hissong, B. D., Li, D., Durum, S. K., Jiang, Q., Bhandoola, A., Hennighausen, L., and O'Shea, J. J. (2006) Stat5a/b are essential for normal lymphoid development and differentiation, Proc. Natl. Acad. Sci. U.S.A. 103, 1000-1005.
20. Ballen, K. K., Ritchie, A. J., Murphy, C., Handin, R. I., and Ewenstein, B. M. (1996) Expression and activation of protein kinase C isoforms in a human megakaryocytic cell line, Exp. Hematol. 24, 1501-1508.
21. Rigacci, S., Rovida, E., Bagnoli, S., Dello Sbarba, P., and Berti, A.(1999) Low M(r) phosphotyrosine protein phosphatase activity on fibroblast growth factor receptor is not associated with enzyme translocation, FEBS Lett. 459, 191-194.
22. Rovida, E., Rigacci, S., Paccagnini, A., Dello Sbarba, P., and Berti, A. (1998) The low-molecular-weight phosphotyrosine protein phosphatase, when overexpressed, reduces the mitogenic response to macrophage colony-stimulating factor and tyrosine phosphorylation of its receptor, Biochem. Biophys. Res. Commun. 253, 300-304.
23. Chiarugi, P., Cirri, P., Marra, F., Raugei, G., Camici, G., Manao, G., and Ramponi, G. (1997) LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signalling, Biochem. Biophys. Res. Commun. 238, 676-682.
24. Parri, M., Buricchi, F., Taddei, M. L., Giannoni, E., Raugei, G., Ramponi, G., and Chiarugi, P. (2005) EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase, J. Biol. Chem. 280, 34008-34018.
25. Chiarugi, P., Cirri, P., Taddei, L., Giannoni, E., Camici, G., Manao, G., Raugei, G., and Ramponi, G. (2000) The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation, J. Biol. Chem. 275, 4640-4646.
26. Taddei, M. L., Chiarugi, P., Cirri, P., Buricchi, F., Fiaschi, T., Giannoni, E., Talini, D., Cozzi, G., Formigli, L., Raugei, G., and Ramponi, G. (2002) Beta-catenin interacts with low-molecular weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase, Cancer Res. 62, 6489-6499.
27. Bucciantini, M., Chiarugi, P., Cirri, P., Taddei, L., Stefani, M., Raugei, G., Nordlund, P., and Ramponi, G. (1999) The low Mr phosphotyrosine protein phosphatase behaves differently when phosphorylated at Tyr131 or Tyr132 by Src kinase, FEBS Lett. 456, 73-78.
28. Blom, N., Gammeltoft, S., and Brunak, S. (1999) Sequence and structure-based prediction of eukaryotic protein phosphorylation sites, J. Mol. Biol. 294, 1351-1362.
29. Blom, N., Sicheritz-Ponten, T., Gupta, R., and Brunak, S. (2004) Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence, Proteomics 4, 1633-1649.
30. Vinkemeier, U. (2004) Getting the message across, STAT! Design principles of a molecular signaling circuit, J. Cell Biol. 167, 197-201.
31. Meyer, T., Begitt, A., Lödige, I., van Rossum, M., and Vinkemeier, U. (2002) Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways, EMBO J. 21, 344-354.
32. Marg, A., Shan, Y., Meyer, T., Meissner, T., Brandenburg, M., and Vinkemeier, U. (2004) Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1, J. Cell Biol. 165, 823-833.
33. Sekimoto, T., Nakajima, K., Tachibana, T., Hirano, T., and Yoneda, Y. (1997) Interferon-gamma-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4, J. Biol. Chem. 271, 31017-31020.
34. Meyer, T., Marg, A., Lemke, P., Wiesner, B., and Vinkemeier, U. (2003) DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1, Genes Dev. 17, 1992-2005.