Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 4, 2008, Pages 1293-1296

  Wang, Zhengqiang ^a   Vince, Robert ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Dual inhibitor; HIV; Integrase; Rational design; Reverse transcriptase

Indexed keywords

INTEGRASE INHIBITOR; PYRIMIDINE DERIVATIVE; QUINOLONE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS;

ANTI-HIV AGENTS; HIV INTEGRASE INHIBITORS; HIV REVERSE TRANSCRIPTASE; PYRIMIDINES; QUINOLONES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38949192885     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.01.025     Document Type: Article

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