Expression and functional analysis of aspartate transcarbamoylase and role of de novo pyrimidine synthesis in regulation of growth and development in Arabidopsis

Plant Physiology and Biochemistry

Volumn 46, Issue 2, 2008, Pages 150-159

  Chen, Celine T ^a   Slocum, Robert D ^a  

^a GOUCHER COLLEGE   (United States)

Author keywords

Arabidopsis; Aspartate transcarbamoylase; PYRB; Pyrimidine nucleotide biosynthesis; RNAi

Indexed keywords

ARABIDOPSIS PROTEIN; ASPARTATE CARBAMOYLTRANSFERASE; PYRIMIDINE; PYRIMIDINE DERIVATIVE;

ARABIDOPSIS; ARTICLE; BIOLOGICAL MODEL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEEDLING;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; ASPARTATE CARBAMOYLTRANSFERASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, PLANT; MODELS, BIOLOGICAL; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEEDLING;

ARABIDOPSIS;

EID: 38949185332     PISSN: 09819428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plaphy.2007.10.016     Document Type: Article

References (33)

1. Moffatt B.A., and Ashihara H. Purine and pyrimidine nucleotide synthesis and metabolism. In: Somerville C.R., and Meyerowitz E.M. (Eds). The Arabidopsis Book (2002), American Society of Plant Biologists, Rockville, MD. http://www.aspb.org/publications/arabidopsis 10.1199/tab.0018
2. Stasolla C., Katahira R., Thorpe T.A., and Ashihara H. Purine and pyrimidine nucleotide metabolism in higher plants. J. Plant Physiol. 160 (2003) 1271-1295
3. Zrenner R., Stitt M., Sonnewald U., and Boldt R. Pyrimidine and purine biosynthesis and degradation in plants. Annu. Rev. Plant Biol. 57 (2006) 805-836
4. Wagner K.G., and Backer A.I. Dynamics of nucleotides in plants studied on a cellular basis. Int. Rev. Cytol. 134 (1992) 1-84
5. Ashihara H. Changes in activities of the de novo and salvage pathways of pyrimidine nucleotide biosynthesis during germination of black gram [mungo beans] (Phaseolus mungo) seeds. Z. Pflanzenphysiol. 81 (1977) 199-211
6. Bassett E.V., Bouchet B.Y., Carr J.M., Williamson C.L., and Slocum R.D. PALA-mediated pyrimidine starvation increases expression of aspartate transcarbmoylase (pyrB) in Arabidopsis seedlings. Plant Physiol. Biochem. 41 (2003) 695-703
7. Salk Institute Genomic Analysis Lab (http://signal.salk.edu).
8. Schröder M., Giermann N., and Zrenner R. Functional analysis of the pyrimidine de novo synthesis pathway in Solanaceous species. Plant Physiol. 138 (2005) 1926-1938
9. O'Connor T.R., Dyreson C., and Wyrick J.J. Athena: a resource for rapid visualization and systematic analysis of Arabidopsis promoter sequences. Bioinformatics 21 (2005) 4411-4413
10. Eshed Y., Baum S.F., and Bowman J.L. Distinct mechanisms promote polarity establishment in carpels of Arabidopsis. Cell 99 (1999) 199-209
11. Chuang C.-F., and Meyerowitz E.M. Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 4985-4990
12. Gleave A.P. A versatile binary vector system with a T-DNA organizational structure conducive to efficient integration of cloned DNA into the plant genome. Plant Mol. Biol. 20 (1992) 1203-1207
13. Nasr F., Bertauche N., Dufour M.-E., Minet M., and Lacroute F. Heterospecific cloning of Arabidopsis thaliana DNAs by direct complementation of pyrimidine auxotrophic mutants of Saccharomyces cerevisiae I. Cloning and sequence analysis of two cDNAs catalyzing the second, fifth and sixth steps of the de novo pyrimidine biosynthesis pathway. Mol. Gen. Genet. 244 (1994) 23-32
14. L-DNA gene 5 controls the tissue-specific expression of chimaeric genes carried by a novel type of Agrobacterium binary vector. Mol. Gen. Genet. 204 (1986) 383-396
15. Clough S.J., and Bent A.F. Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16 (1998) 735-743
16. Geisler M., Jablonska B., and Springer P.S. Enhancer trap expression patterns provide a novel teaching resource. Plant Physiol. 130 (2002) 1747-1753
17. Yu D., Chen C., and Chen Z. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell 13 (2001) 1527-1540
18. Chung B.Y.W., Simons C., Firth A.E., Brown C.M., and Hellens R.P. Effect of 5′UTR introns on gene expression in Arabidopsis thaliana. BMC Genomics 7 (2006) 120 10.1186/1471-2164-7-120
19. Sasamoto H., Saito K., and Ashihara H. Metabolism of pyrimidines in protoplasts from cultured Catharanthus roseus cells. Ann. Bot 60 (1987) 417-420
20. Khan A.I., Chowdhry B.Z., and Yon R.J. Wheat-germ aspartate transcarbamoylase: revised purification, stability and re-evaluation of regulatory kinetics in terms of Monad-Wyman-Changeux model. Eur. J. Biochem. 259 (1999) 71-78
21. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215 (1990) 403-410
22. Walther R., Wald K., Glund K., and Tewes A. Evidence that a single polypeptide catalyzes the two step conversion of orotate to UMP in cells from tomato suspension culture. J. Plant Physiol. 116 (1984) 301-311
23. Santoso D., and Thornburg R. UMP synthase is transcriptionally regulated by pyrimidine levels in Nicotiana plumbaginifolia. Plant Physiol. 116 (1998) 815-821
24. Hewitt M.M., Carr J.M., Williamson C.L., and Slocum R.D. Effects of phosphate limitation on expression of genes involved in pyrimidine synthesis and salvaging in Arabidopsis. Plant Physiol. Biochem. 43 (2005) 91-99
25. Doremus H.D., and Jagendorf A.T. Subcellular localization of the pathway of de novo pyrimidine nucleotide biosynthesis in pea leaves. Plant Physiol. 79 (1985) 856-861
26. Scheible W.-R., Morcuende R., Czechowski T., Fritz C., Osuna D., Palacios-Rojas N., Schindelasch D., Thimm O., Udvardi M.K., and Stitt M. Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen. Plant Physiol. 136 (2004) 2483-2499
27. Thimm O., Blasing O., Gibon Y., Nagel A., Meyer S., Kruger P., Selbig J., Muller L.A., Rhee S.Y., and Stitt M. MAPMAN: a user-driven tool to display genomics data sets onto diagrams of metabolic pathways and other biological processes. Plant J. 37 (2004) 914-939
28. Coruzzi G.M. Primary N-assimilation into amino acids in Arabidopsis. In: Somerville C.R., and Meyerowitz E.M. (Eds). The Arabidopsis Book (2003), American Society of Plant Biologists, Rockville, MD. http://www.aspb.org/publications/arabidopsis 10.1199/tab.0010
29. Euglem T. Dissecting the WRKY web of plant defense regulators. PLOS Pathogen 2 (2006) e126 10.1371/journal.ppat.0020126
30. Wu K.-L., Guo Z.-J., Wang H.-H., and Li J. The WRKY family of transcription factors in rice and Arabidopsis and their origins. DNA Res. 12 (2005) 9-26
31. Meyer R., and Wagner K.G. Analysis of the nucleotide pool during growth of suspension cultured cells of Nicotiana tabacum by high performance liquid chromatography. Physiol. Plant 65 (1985) 439-445
32. Geigenberger W.P., Regierer B., Nunes-Nesi A., Leisse A., Urbanczyk-Wochniak E., Springer F., van Dongen J.T., Kossmann J., and Ferniea A.R. Inhibition of de novo pyrimidine synthesis in growing potato tubers leads to a compensatory stimulation of the pyrimidine salvage pathway and a subsequent increase in biosynthetic performance. Plant Cell 17 (2005) 2077-2088
33. The A. thaliana Co-Re sponse Database (http://csbdb.mpimp-golm.mpg.de/csbdb/dbcor/ath.html).