The use of MPA amide for the assignment of absolute configuration of a sterically hindered cyclic secondary amine by 'mix and shake' NMR method

Magnetic Resonance in Chemistry

Volumn 46, Issue 1, 2008, Pages 17-22

  Gao, Jinhai ^a   Haas, Hansjoerg ^b   Wang, Kate Yaping ^a   Chen, Zhuoliang ^a   Breitenstein, Werner ^b   Rajan, Srinivasan ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

1H NMR; Absolute configuration; Cyclic secondary amine; MPA amide

Indexed keywords

AMINES; CONFORMATIONS; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

1H NMR; ABSOLUTE CONFIGURATION; ASSIGNMENT OF ABSOLUTE CONFIGURATION; CONFORMATIONAL ANALYSIS; CYCLIC SECONDARY AMINE; DIASTEREOMERIC AMIDES; METHOXYPHENYLACETIC ACID AMIDE; MOLECULAR MECHANICS CALCULATIONS; NMR EXPERIMENTS; SECONDARY AMINES;

AMIDES;

EID: 38949128377     PISSN: 07491581     EISSN: 1097458X     Source Type: Journal    
DOI: 10.1002/mrc.2115     Document Type: Article

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