SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 4, 2008, Pages 1461-1467

  Dols, Paul P M A ^a   Folmer, Brigitte J B ^a   Hamersma, Hans ^a   Kuil, Cor W ^a   Lucas, Hans ^a   Ollero, Lourdes ^a   Rewinkel, Jos B M ^a   Hermkens, Pedro H H ^a  

^a NV ORGANON   (Netherlands)

Author keywords

Agonist; Non steroidal; Progesterone receptor

Indexed keywords

OXAZEPINE DERIVATIVE; PROGESTERONE RECEPTOR MODULATOR;

ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

BINDING SITES; MODELS, MOLECULAR; OXAZEPINES; PROGESTERONE; RECEPTORS, PROGESTERONE; STRUCTURE-ACTIVITY RELATIONSHIP; TRIFLUOROACETIC ACID;

EID: 38949119757     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.12.065     Document Type: Article

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