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Volumn 15, Issue 3, 2008, Pages 177-184

Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells

Author keywords

Activator protein 1; Cytokine mRNA; Luteolin; RBL 2H3; Thunberginol A; Thunberginol B

Indexed keywords

CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; ISOCOUMARIN DERIVATIVE; LUTEOLIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS; STRESS ACTIVATED PROTEIN KINASE; THUNBERGINOL A; THUNBERGINOL B; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 38949106117     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2007.09.010     Document Type: Article
Times cited : (28)

References (22)
  • 1
    • 0033951038 scopus 로고    scopus 로고
    • Using photolabile ligands in drug discovery and development
    • Dorman G., and Prestwich G.D. Using photolabile ligands in drug discovery and development. Trends Biotechnol. 18 (2000) 64-77
    • (2000) Trends Biotechnol. , vol.18 , pp. 64-77
    • Dorman, G.1    Prestwich, G.D.2
  • 5
    • 0032213365 scopus 로고    scopus 로고
    • Inhibition by dexamethasone of antigen-induced c-jun N-terminal kinase activation in rat basophilic leukemia cells
    • Hirasawa N., Sato Y., Fujita Y., Mue S., and Ohuchi K. Inhibition by dexamethasone of antigen-induced c-jun N-terminal kinase activation in rat basophilic leukemia cells. J. Immunol. 161 (1998) 4939-4943
    • (1998) J. Immunol. , vol.161 , pp. 4939-4943
    • Hirasawa, N.1    Sato, Y.2    Fujita, Y.3    Mue, S.4    Ohuchi, K.5
  • 6
    • 0034598394 scopus 로고    scopus 로고
    • Involvement of a phosphatidylinositol 3-kinase-p38 mitogen activated protein kinase pathway in antigen-induced IL-4 production in mast cells
    • Hirasawa N., Sato Y., Fujita Y., and Ohuchi K. Involvement of a phosphatidylinositol 3-kinase-p38 mitogen activated protein kinase pathway in antigen-induced IL-4 production in mast cells. Biochim. Biophys. Acta 1456 (2000) 45-55
    • (2000) Biochim. Biophys. Acta , vol.1456 , pp. 45-55
    • Hirasawa, N.1    Sato, Y.2    Fujita, Y.3    Ohuchi, K.4
  • 7
    • 0029666270 scopus 로고    scopus 로고
    • Aggregation of FcεRI on mast cells stimulates c-jun amino-terminal kinase activity
    • Ishizuka T., Oshiba A., Sakata N., Terada N., Johnson G.L., and Gelfand E.W. Aggregation of FcεRI on mast cells stimulates c-jun amino-terminal kinase activity. J. Biol. Chem. 271 (1996) 12762-12766
    • (1996) J. Biol. Chem. , vol.271 , pp. 12762-12766
    • Ishizuka, T.1    Oshiba, A.2    Sakata, N.3    Terada, N.4    Johnson, G.L.5    Gelfand, E.W.6
  • 9
    • 0036037498 scopus 로고    scopus 로고
    • Inhibition of TNF-α and IL-6 production by aucubin through blockade of NF-κB activation RBL-2H3 mast cells
    • Jeong H.J., Koo H.N., Na H.J., Kim M.S., Hong S.H., Eim J.W., Kom K.S., Shin T.Y., and Kim H.M. Inhibition of TNF-α and IL-6 production by aucubin through blockade of NF-κB activation RBL-2H3 mast cells. Cytokine 18 (2002) 252-259
    • (2002) Cytokine , vol.18 , pp. 252-259
    • Jeong, H.J.1    Koo, H.N.2    Na, H.J.3    Kim, M.S.4    Hong, S.H.5    Eim, J.W.6    Kom, K.S.7    Shin, T.Y.8    Kim, H.M.9
  • 10
    • 0034062416 scopus 로고    scopus 로고
    • Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells
    • Kimata M., Shichijo M., Miura T., Serizawa I., Inagaki N., and Nagai H. Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells. Clin. Exp. Allergy 30 (2000) 501-508
    • (2000) Clin. Exp. Allergy , vol.30 , pp. 501-508
    • Kimata, M.1    Shichijo, M.2    Miura, T.3    Serizawa, I.4    Inagaki, N.5    Nagai, H.6
  • 11
    • 0038404908 scopus 로고    scopus 로고
    • Role of activator protein 1, nuclear factor-κB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells
    • Lorentz A., Klopp I., Gebhardt T., Manns M.P., and Bischoff S.C. Role of activator protein 1, nuclear factor-κB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. J. Allergy Clin. Immunol. 111 (2003) 1062-1068
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 1062-1068
    • Lorentz, A.1    Klopp, I.2    Gebhardt, T.3    Manns, M.P.4    Bischoff, S.C.5
  • 12
    • 1542315613 scopus 로고    scopus 로고
    • Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells
    • Matsubara M., Masaki S., Ohmori K., Karasawa A., and Hasegawa K. Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells. Biochem. Pharmacol. 67 (2004) 1315-1326
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 1315-1326
    • Matsubara, M.1    Masaki, S.2    Ohmori, K.3    Karasawa, A.4    Hasegawa, K.5
  • 13
    • 0032842469 scopus 로고    scopus 로고
    • The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation
    • Matsuda H., Shimoda H., Kageura T., and Yoshikawa M. The role of thunberginol A, an isocoumarin constituent of Hydrangeae Dulcis Folium, on the signal transmission pathway for rat mast cell degranulation. Biol. Pharm. Bull. 22 (1999) 925-931
    • (1999) Biol. Pharm. Bull. , vol.22 , pp. 925-931
    • Matsuda, H.1    Shimoda, H.2    Kageura, T.3    Yoshikawa, M.4
  • 14
    • 0032861912 scopus 로고    scopus 로고
    • Effects of phylloducin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats
    • Matsuda H., Shimoda H., Yamahara J., and Yoshikawa M. Effects of phylloducin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Biol. Pharm. Bull. 22 (1999) 870-872
    • (1999) Biol. Pharm. Bull. , vol.22 , pp. 870-872
    • Matsuda, H.1    Shimoda, H.2    Yamahara, J.3    Yoshikawa, M.4
  • 15
    • 0033041711 scopus 로고    scopus 로고
    • Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells
    • Matsuda H., Shimoda H., and Yoshikawa M. Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells. Bioorg. Med. Chem. 7 (1999) 1445-1450
    • (1999) Bioorg. Med. Chem. , vol.7 , pp. 1445-1450
    • Matsuda, H.1    Shimoda, H.2    Yoshikawa, M.3
  • 16
    • 0036340280 scopus 로고    scopus 로고
    • Structural requirements of flavonoids for inhibition of antigen-induced degranulation, TNF-α and IL-4 production from RBL-2H3 cells
    • Matsuda H., Morikawa T., Ueda K., Managi H., and Yoshikawa M. Structural requirements of flavonoids for inhibition of antigen-induced degranulation, TNF-α and IL-4 production from RBL-2H3 cells. Bioorg. Med. Chem. 10 (2002) 3123-3128
    • (2002) Bioorg. Med. Chem. , vol.10 , pp. 3123-3128
    • Matsuda, H.1    Morikawa, T.2    Ueda, K.3    Managi, H.4    Yoshikawa, M.5
  • 17
    • 0032403191 scopus 로고    scopus 로고
    • Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 componet at the TNF-α promoter in stimulated mast cells
    • Novotny V., Prieschl E.E., Csonga R., Fabjani G., and Baumruker T. Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 componet at the TNF-α promoter in stimulated mast cells. Nucleic Acid Res. 26 (1998) 5480-5485
    • (1998) Nucleic Acid Res. , vol.26 , pp. 5480-5485
    • Novotny, V.1    Prieschl, E.E.2    Csonga, R.3    Fabjani, G.4    Baumruker, T.5
  • 18
    • 0034713675 scopus 로고    scopus 로고
    • Immunologically medited signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcεRI signaling pathway
    • Oliver J.M., Kepley C.L., Ortega E., and Wilson B.S. Immunologically medited signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcεRI signaling pathway. Immunopharmacology 48 (2000) 269-281
    • (2000) Immunopharmacology , vol.48 , pp. 269-281
    • Oliver, J.M.1    Kepley, C.L.2    Ortega, E.3    Wilson, B.S.4
  • 19
    • 0015042543 scopus 로고
    • Regulation of homocytotropic antibody formation in the rat. I. Feed-back regulation by passively administered antibody
    • Tada T., and Okumura K. Regulation of homocytotropic antibody formation in the rat. I. Feed-back regulation by passively administered antibody. J. Immunol. 106 (1971) 1002-1011
    • (1971) J. Immunol. , vol.106 , pp. 1002-1011
    • Tada, T.1    Okumura, K.2
  • 20
    • 33846942253 scopus 로고    scopus 로고
    • Inhibitory effects of thunberginols A, B, and F on degranulations and releases of TNF-α and IL-4 in RBL-2H3 cells
    • Wang Q., Matsuda H., Matsuhira K., Nakamura S., Yuan D., and Yoshikawa M. Inhibitory effects of thunberginols A, B, and F on degranulations and releases of TNF-α and IL-4 in RBL-2H3 cells. Biol. Pharm. Bull. 30 (2007) 388-392
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 388-392
    • Wang, Q.1    Matsuda, H.2    Matsuhira, K.3    Nakamura, S.4    Yuan, D.5    Yoshikawa, M.6
  • 21
    • 0026947814 scopus 로고
    • Thunberginols A, B, and F, new antiallergic and antimicrobial principles from Hydrangeae Dulcis Folium
    • Yoshikawa M., Uchida E., Chatani N., Murakami N., and Yamahara J. Thunberginols A, B, and F, new antiallergic and antimicrobial principles from Hydrangeae Dulcis Folium. Chem. Pharm. Bull. 40 (1992) 3121-3123
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 3121-3123
    • Yoshikawa, M.1    Uchida, E.2    Chatani, N.3    Murakami, N.4    Yamahara, J.5
  • 22
    • 0027940676 scopus 로고
    • Development of bioactive functions in Hydrangeae Dulcis Folium. III. On the antiallergic and antimicrobial principles of Hydrangeae dulcis folium. (1). Thunberginols A, B, and F
    • Yoshikawa M., Harada E., Naitoh Y., Inoue K., Matsuda H., Shimoda H., Yamahara J., and Murakami N. Development of bioactive functions in Hydrangeae Dulcis Folium. III. On the antiallergic and antimicrobial principles of Hydrangeae dulcis folium. (1). Thunberginols A, B, and F. Chem. Pharm. Bull. 42 (1994) 2225-2230
    • (1994) Chem. Pharm. Bull. , vol.42 , pp. 2225-2230
    • Yoshikawa, M.1    Harada, E.2    Naitoh, Y.3    Inoue, K.4    Matsuda, H.5    Shimoda, H.6    Yamahara, J.7    Murakami, N.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.