Inhibitory effects of thunberginols A, B, and F on degranulations and releases of TNF-α and IL-4 in RBL-2H3 cells

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 2, 2007, Pages 388-392

  Wang, Qilong ^a,b   Matsuda, Hisashi ^a   Matsuhira, Koudai ^a   Nakamura, Seikou ^a   Yuan, Dan ^b   Yoshikawa, Masayuki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Degranulation; Hydrangea macrophylla var. thunbergii; Interleukin (IL 4); Thunberginol; Tumor necrosis factor (TNF )

Indexed keywords

3' HYDROXYHYDRANGEAIC ACID; ANTIALLERGIC AGENT; ANTIGEN; CALCIMYCIN; CALCIUM ION; HERBACEOUS AGENT; HYDRANGENOL; HYDROXYL GROUP; INTERLEUKIN 4; LACTONE; PHYLLODULCIN; THUNBERGINOL A; THUNBERGINOL B; THUNBERGINOL C; THUNBERGINOL E; THUNBERGINOL F; THUNBERGINOL G; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CHEMICAL BOND; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEGRANULATION; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; HYDRANGEA; HYDRANGEA MACROPHYLLA; NONHUMAN; PLANT LEAF; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIGENS; BETA-N-ACETYLHEXOSAMINIDASES; CALCIMYCIN; CALCIUM; CELL DEGRANULATION; CELL LINE, TUMOR; DINITROPHENOLS; HYDRANGEA; INTERLEUKIN-4; IONOPHORES; ISOCOUMARINS; PLANT LEAVES; RATS; SERUM ALBUMIN, BOVINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33846942253     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.388     Document Type: Article

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