SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells

Virology

Volumn 372, Issue 1, 2008, Pages 127-135

  Mossel, Eric C ^a   Wang, Jieru ^b   Jeffers, Scott ^c   Edeen, Karen E ^b   Wang, Shuanglin ^b   Cosgrove, Gregory P ^b   Funk, C Joel ^b   Manzer, Rizwan ^b   Miura, Tanya A ^c   Pearson, Leonard D ^a   Holmes, Kathryn V ^c   Mason, Robert J ^b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

ACE2; Alveolar macrophage; Lung; SARS

Indexed keywords

CYTOKERATIN; EPITHELIAL CELL ADHESION MOLECULE; GENOMIC RNA; LUNG SURFACTANT; MONOCLONAL ANTIBODY; PROTEIN SP A; PROTEIN SP C; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS CELL TYPE 2; LUNG FIBROBLAST; MACROPHAGE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARS CORONAVIRUS; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TITRATION;

CELL DIFFERENTIATION; CELLS, CULTURED; CYTOPATHOGENIC EFFECT, VIRAL; EPITHELIUM; HUMANS; PULMONARY ALVEOLI; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SARS VIRUS; VIROLOGY; VIRUS REPLICATION;

SARS CORONAVIRUS;

EID: 38949084217     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.09.045     Document Type: Article

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