Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in human carbonic anhydrase II linked to marble brain disease

Biochemistry

Volumn 47, Issue 5, 2008, Pages 1288-1298

  Almstedt, Karin ^a   Mårtensson, Lars Göran ^a   Carlsson, Uno ^a   Hammarström, Per ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BRAIN; ENZYMES; GENES; PHASE DIAGRAMS; PHYSIOLOGY; THERMODYNAMIC STABILITY;

CARBONIC ANHYDRASE PROTEINS; FOLDING MUTATION; MUTANT MAPPING;

DISEASES;

ASPARAGINE; CARBONATE DEHYDRATASE II; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; BETA SHEET; BRAIN DISEASE; DENATURATION; GUIBAUD VAINSEL SYNDROME; HEAT TREATMENT; HYDROGEN BOND; MARBLE BRAIN DISEASE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; THERMODYNAMICS;

ACETAZOLAMIDE; AMINO ACID SUBSTITUTION; BRAIN DISEASES, METABOLIC, INBORN; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; ENZYME STABILITY; GUANIDINE; HEAT; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS;

EID: 38849183444     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701720p     Document Type: Article

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