Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures

British Journal of Pharmacology

Volumn 153, Issue 3, 2008, Pages 528-535

  Elsas, P X ^a,b   Queto, T ^c   Mendonca Sales S C ^c   Elsas, M I G ^c   Kanaoka, Y ^b   Lam, B K ^b  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

5 lipoxygenase; Bone marrow; COX; Cysteinyl leukotriene; Eosinophils; Haematopoiesis; NSAID

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ACETYLSALICYLIC ACID; ARACHIDONATE 5 LIPOXYGENASE; INDOMETACIN; INTERLEUKIN 5; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; MONTELUKAST; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN E2; VERLUKAST; ZILEUTON;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BAGG ALBINO MOUSE; BONE MARROW CULTURE; DRUG EFFECT; ENZYME SYNTHESIS; EOSINOPHIL; FEMALE; GENE INACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BONE MARROW CELLS; CARRIER PROTEINS; CELLS, CULTURED; CYCLOOXYGENASE INHIBITORS; CYSTEINE; DINOPROSTONE; EOSINOPHILS; FEMALE; GLUTATHIONE TRANSFERASE; INDOMETHACIN; LEUKOTRIENES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; SIGNAL TRANSDUCTION;

EID: 38849175586     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707586     Document Type: Article

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