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Volumn 121, Issue 2, 2008, Pages 361-368

Role of obesity in complicating and confusing the diagnosis and treatment of diabetes in children

Author keywords

Insulin resistance; Maturity onset diabetes of the young; Obesity; Type 1 diabetes; Type 2 diabetes

Indexed keywords

ANTIDIABETIC AGENT;

EID: 38849119173     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2007-1234     Document Type: Review
Times cited : (33)

References (60)
  • 1
    • 0004318660 scopus 로고    scopus 로고
    • World Health Organization, Geneva, Switzerland: World Health Organization;, WHO technical report series 894
    • World Health Organization. Obesity: Preventing and Managing the Global Epidemic. Geneva, Switzerland: World Health Organization; 2000. WHO technical report series 894
    • (2000) Obesity: Preventing and Managing the Global Epidemic
  • 2
    • 0035852037 scopus 로고    scopus 로고
    • Epidemic increase in childhood overweight, 1986-1998
    • Strauss RS, Pollack HA. Epidemic increase in childhood overweight, 1986-1998. JAMA. 2001;286(22):2845-2848
    • (2001) JAMA , vol.286 , Issue.22 , pp. 2845-2848
    • Strauss, R.S.1    Pollack, H.A.2
  • 4
    • 0346101590 scopus 로고    scopus 로고
    • Body mass index and overweight in adolescents in 13 European countries, Israel, and the United States
    • Lissau I, Overpeck MD, Ruan WJ, et al. Body mass index and overweight in adolescents in 13 European countries, Israel, and the United States. Arch Pediatr Adolesc Med. 2004;158(1):27-33
    • (2004) Arch Pediatr Adolesc Med , vol.158 , Issue.1 , pp. 27-33
    • Lissau, I.1    Overpeck, M.D.2    Ruan, W.J.3
  • 6
    • 0032162184 scopus 로고    scopus 로고
    • evaluation, and treatment of overweight and obesity in adults: The evidence report. National Institutes of Health
    • National Heart Lung and Blood Institute Clinical guidelines on the identification
    • National Heart Lung and Blood Institute Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. National Institutes of Health. Obes Res. 1998;6(suppl 2):51S-209S
    • (1998) Obes Res , vol.6 , Issue.SUPPL. 2
  • 7
    • 33244486544 scopus 로고    scopus 로고
    • Impact of obesity on rising medical spending: Health Tracking 2004 American Diabetes Association Position Statement. Diagnosis and Classification of Diabetes Mellitus
    • Thorpe KE, Florence CS, Howard DH, Joski P. Impact of obesity on rising medical spending: Health Tracking 2004 American Diabetes Association Position Statement. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2006;29(suppl 1):S43-S48
    • (2006) Diabetes Care , vol.29 , Issue.SUPPL. 1
    • Thorpe, K.E.1    Florence, C.S.2    Howard, D.H.3    Joski, P.4
  • 8
    • 0003512785 scopus 로고
    • World Health Organization:, Geneva, Switzerland: World Health Organization;, WHO technical report series 727
    • World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, Switzerland: World Health Organization; 1985. WHO technical report series 727
    • (1985) Diabetes Mellitus: Report of a WHO Study Group
  • 9
    • 4143151942 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus
    • DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am. 2004;88(4):787-835
    • (2004) Med Clin North Am , vol.88 , Issue.4 , pp. 787-835
    • DeFronzo, R.A.1
  • 10
    • 0024425880 scopus 로고
    • Maturity onset diabetes of the young (MODY)
    • Fajans SS. Maturity onset diabetes of the young (MODY). Diabetes Metab Rev. 1989;5(7):579-606
    • (1989) Diabetes Metab Rev , vol.5 , Issue.7 , pp. 579-606
    • Fajans, S.S.1
  • 11
    • 0344837809 scopus 로고    scopus 로고
    • A genome-wide scan in families with maturity-onset diabetes of the young: Evidence for further genetic heterogeneity
    • Frayling TM, Lindgren CM, Chevre JC, et al. A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity. Diabetes. 2003;52(3):872-881
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 872-881
    • Frayling, T.M.1    Lindgren, C.M.2    Chevre, J.C.3
  • 12
    • 33646778478 scopus 로고    scopus 로고
    • Minireview: Pharmacogenetics and beyond - the interaction of therapeutic response, beta cell physiology, and genetics in diabetes
    • Hattersley AT, Pearson AE. Minireview: pharmacogenetics and beyond - the interaction of therapeutic response, beta cell physiology, and genetics in diabetes. Endocrinology. 2006;147(6):2657-2663
    • (2006) Endocrinology , vol.147 , Issue.6 , pp. 2657-2663
    • Hattersley, A.T.1    Pearson, A.E.2
  • 13
    • 0842285626 scopus 로고    scopus 로고
    • Mitochondrial diabetes: Molecular mechanisms and clinical presentation
    • Maassen JA, 'T Hart LM, van Essen E, et al. Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes. 2004;53(suppl 1):S103-S109
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Maassen, J.A.1    'T Hart, L.M.2    van Essen, E.3
  • 14
    • 33646513278 scopus 로고    scopus 로고
    • Mutations in KCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype
    • Flanagan SE, Edghill AE, Gloyn AL, Ellard S, Hattersley AT. Mutations in KCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype. Diabetologia. 2006;49(6):1190-1197
    • (2006) Diabetologia , vol.49 , Issue.6 , pp. 1190-1197
    • Flanagan, S.E.1    Edghill, A.E.2    Gloyn, A.L.3    Ellard, S.4    Hattersley, A.T.5
  • 15
    • 33846851524 scopus 로고    scopus 로고
    • The genetic basis of neonatal diabetes mellitus
    • Sperling MA. The genetic basis of neonatal diabetes mellitus. Pediatr Endocrinol Rev. 2006;(4 suppl 1):71-75
    • (2006) Pediatr Endocrinol Rev , vol.4 , Issue.SUPPL. 1 , pp. 71-75
    • Sperling, M.A.1
  • 16
    • 0026577332 scopus 로고
    • Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss: Effect on muscle glucose transport and glucose transporter GLUT4
    • Friedman JE, Dohm GL, Leggett-Frazier CW, et al. Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss: effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest. 1992;89(2):701-705
    • (1992) J Clin Invest , vol.89 , Issue.2 , pp. 701-705
    • Friedman, J.E.1    Dohm, G.L.2    Leggett-Frazier, C.W.3
  • 17
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006;444(7121):840-846
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 18
    • 0035522298 scopus 로고    scopus 로고
    • Resistin, obesity, and insulin resistance: The emerging role of the adipocyte as an endocrine organ
    • Shuldiner AR, Yang R, Gong DW. Resistin, obesity, and insulin resistance: the emerging role of the adipocyte as an endocrine organ. N Engl J Med. 2001;345(18):1345-1346
    • (2001) N Engl J Med , vol.345 , Issue.18 , pp. 1345-1346
    • Shuldiner, A.R.1    Yang, R.2    Gong, D.W.3
  • 19
    • 0037269011 scopus 로고    scopus 로고
    • Adipobiology of disease: Adipokines and adipokine-targeted pharmacology
    • Chaldakov GN, Stankulov IS, Hristova M, Ghenev PI. Adipobiology of disease: adipokines and adipokine-targeted pharmacology. Curr Pharm Des. 2003;9(12):1023-1031
    • (2003) Curr Pharm Des , vol.9 , Issue.12 , pp. 1023-1031
    • Chaldakov, G.N.1    Stankulov, I.S.2    Hristova, M.3    Ghenev, P.I.4
  • 20
    • 0036348363 scopus 로고    scopus 로고
    • Ectopic fat accumulation: An important cause of insulin resistance in humans
    • Yki-Jarvinen H. Ectopic fat accumulation: an important cause of insulin resistance in humans. J R Soc Med. 2002;95(suppl 42):39-45
    • (2002) J R Soc Med , vol.95 , Issue.SUPPL. 42 , pp. 39-45
    • Yki-Jarvinen, H.1
  • 21
    • 0038306907 scopus 로고    scopus 로고
    • Insulin resistance/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease
    • Reaven GM. Insulin resistance/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease. J Clin Endocrinol Metab. 2003;88(6):2399-2403
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.6 , pp. 2399-2403
    • Reaven, G.M.1
  • 23
    • 0014289803 scopus 로고
    • Plasma glucose, free fatty acids, and immunoreactive insulin in sixty-six obese children
    • Paulson EP, Richenderfer L, Ginsberg-Fellner F. Plasma glucose, free fatty acids, and immunoreactive insulin in sixty-six obese children. Diabetes. 1968;17(5):261-269
    • (1968) Diabetes , vol.17 , Issue.5 , pp. 261-269
    • Paulson, E.P.1    Richenderfer, L.2    Ginsberg-Fellner, F.3
  • 24
    • 0029692186 scopus 로고    scopus 로고
    • Non-insulin-dependent diabetes in children and adolescents
    • Glaser N, Jones KL. Non-insulin-dependent diabetes in children and adolescents. Adv Pediatr. 1996;43:359-396
    • (1996) Adv Pediatr , vol.43 , pp. 359-396
    • Glaser, N.1    Jones, K.L.2
  • 25
    • 0031891229 scopus 로고    scopus 로고
    • NIDDM-Y in First Nation children in Canada
    • Dean H. NIDDM-Y in First Nation children in Canada. Clin Pediatr (Phila). 1998;37(2):89-96
    • (1998) Clin Pediatr (Phila) , vol.37 , Issue.2 , pp. 89-96
    • Dean, H.1
  • 26
    • 0018693524 scopus 로고
    • High prevalence of diabetes in young Pima Indians
    • Savage PJ, Bennett PH, Senter RG, Miller M. High prevalence of diabetes in young Pima Indians. Diabetes. 1979;28(10):937-942
    • (1979) Diabetes , vol.28 , Issue.10 , pp. 937-942
    • Savage, P.J.1    Bennett, P.H.2    Senter, R.G.3    Miller, M.4
  • 27
    • 0034035943 scopus 로고    scopus 로고
    • Type 2 diabetes among North American children and adolescents: An epidemiological review and a public health perspective
    • Fagot-Campagna A, Pettitt DJ, Engelgau MM, et al. Type 2 diabetes among North American children and adolescents: an epidemiological review and a public health perspective. J Pediatr. 2000;136(5):664-672
    • (2000) J Pediatr , vol.136 , Issue.5 , pp. 664-672
    • Fagot-Campagna, A.1    Pettitt, D.J.2    Engelgau, M.M.3
  • 28
    • 18144382988 scopus 로고    scopus 로고
    • The global spread of type 2 diabetes mellitus in children and adolescents
    • Pinhas-Hamiel O, Zeitler P. The global spread of type 2 diabetes mellitus in children and adolescents. J Pediatr. 2005;146(5):693-700
    • (2005) J Pediatr , vol.146 , Issue.5 , pp. 693-700
    • Pinhas-Hamiel, O.1    Zeitler, P.2
  • 29
    • 0041823273 scopus 로고    scopus 로고
    • Prevalence of diagnosed diabetes among African-American and non-Hispanic white youth
    • Oeltmann JE, Liese AD, Heinze HJ, Addy CL, Mayer-Davis EJ. Prevalence of diagnosed diabetes among African-American and non-Hispanic white youth. Diabetes Care. 2003;26(9):2531-2535
    • (2003) Diabetes Care , vol.26 , Issue.9 , pp. 2531-2535
    • Oeltmann, J.E.1    Liese, A.D.2    Heinze, H.J.3    Addy, C.L.4    Mayer-Davis, E.J.5
  • 30
    • 0041885037 scopus 로고    scopus 로고
    • Presentation and 5 year follow-up of type 2 diabetes mellitus in African-American and Caribbean-Hispanic adolescents
    • Grinstein G, Muzumdar R, Aponte L, Vuguin P, Saenger P, DiMartino-Nardi J. Presentation and 5 year follow-up of type 2 diabetes mellitus in African-American and Caribbean-Hispanic adolescents. Horm Res. 2003;60(3):121-126
    • (2003) Horm Res , vol.60 , Issue.3 , pp. 121-126
    • Grinstein, G.1    Muzumdar, R.2    Aponte, L.3    Vuguin, P.4    Saenger, P.5    DiMartino-Nardi, J.6
  • 31
    • 0034088992 scopus 로고    scopus 로고
    • Type 2 diabetes in children and adolescents
    • American Diabetes Association
    • American Diabetes Association. Type 2 diabetes in children and adolescents. Diabetes Care. 2000;23(3):381-390
    • (2000) Diabetes Care , vol.23 , Issue.3 , pp. 381-390
  • 32
    • 38849150105 scopus 로고    scopus 로고
    • Type 2 diabetes in children and adolescents
    • Daneman D, Hamilton J, eds, Huppauge, NY: Nova Science Publishers, Inc
    • Phillips SA, Jones KL. Type 2 diabetes in children and adolescents. In: Daneman D, Hamilton J, eds. Insulin Resistance in Children and Adolescents. Huppauge, NY: Nova Science Publishers, Inc.; 2005:121-162
    • (2005) Insulin Resistance in Children and Adolescents , pp. 121-162
    • Phillips, S.A.1    Jones, K.L.2
  • 34
    • 0030483737 scopus 로고    scopus 로고
    • The Childhood Diabetes in Finland Study Group: Islet cell-specific autoantibodies in children with insulin-dependent diabetes mellitus and their siblings at clinical manifestation of the disease
    • Vähäsalo P, Knip M, Karjalainen J, Tuomilehto-Wolf E, Lounamaa R, Akerblom HK. The Childhood Diabetes in Finland Study Group: islet cell-specific autoantibodies in children with insulin-dependent diabetes mellitus and their siblings at clinical manifestation of the disease. Eur J Endocrinol. 1996;135(6):689-696
    • (1996) Eur J Endocrinol , vol.135 , Issue.6 , pp. 689-696
    • Vähäsalo, P.1    Knip, M.2    Karjalainen, J.3    Tuomilehto-Wolf, E.4    Lounamaa, R.5    Akerblom, H.K.6
  • 35
    • 0036356213 scopus 로고    scopus 로고
    • Effect of metformin in pediatric patients with type 2 diabetes: A randomized controlled trial
    • Jones KL, Arslanian S, Peterokova VA, Park J-S, Tomlinson MJ. Effect of metformin in pediatric patients with type 2 diabetes: a randomized controlled trial. Diabetes Care. 2002;25(1):89-94
    • (2002) Diabetes Care , vol.25 , Issue.1 , pp. 89-94
    • Jones, K.L.1    Arslanian, S.2    Peterokova, V.A.3    Park, J.-S.4    Tomlinson, M.J.5
  • 36
    • 0033867396 scopus 로고    scopus 로고
    • Genetic, autoimmune and clinical characteristics of childhood- and adult-onset type 1 diabetes
    • Sabbah E, Savola K, Ebeling T, et al. Genetic, autoimmune and clinical characteristics of childhood- and adult-onset type 1 diabetes. Diabetes Care. 2000;23(9):1326-1332
    • (2000) Diabetes Care , vol.23 , Issue.9 , pp. 1326-1332
    • Sabbah, E.1    Savola, K.2    Ebeling, T.3
  • 37
    • 0034457410 scopus 로고    scopus 로고
    • Autoantibody recognition of COOH terminal epitopes of GAD65 marks the risk for insulin requirement in adult-onset diabetes mellitus
    • Falorni A, Gambelunghe G, Forini F, et al. Autoantibody recognition of COOH terminal epitopes of GAD65 marks the risk for insulin requirement in adult-onset diabetes mellitus. J Clin Endocrinol Metab. 2000;85(1):309-613
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.1 , pp. 309-613
    • Falorni, A.1    Gambelunghe, G.2    Forini, F.3
  • 38
    • 0031560175 scopus 로고    scopus 로고
    • UKPDS 25: Autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group
    • Turner R, Stratton I, Horton V, et al. UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet. 1997;350(9087):1288-1293
    • (1997) Lancet , vol.350 , Issue.9087 , pp. 1288-1293
    • Turner, R.1    Stratton, I.2    Horton, V.3
  • 39
    • 33746563454 scopus 로고    scopus 로고
    • GAD antibodies in probands and their relatives in a cohort clinically selected for type 2 diabetes
    • Castleden HAJ, Shields B, Bingley PJ, et al. GAD antibodies in probands and their relatives in a cohort clinically selected for type 2 diabetes. Diabet Med. 2006;23(8):834-838
    • (2006) Diabet Med , vol.23 , Issue.8 , pp. 834-838
    • Castleden, H.A.J.1    Shields, B.2    Bingley, P.J.3
  • 40
    • 0035377557 scopus 로고    scopus 로고
    • Diabetic autoimmune markers in children and adolescents with type 2 diabetes
    • Available at
    • Hathout EH, Thomas W, El-Shahaway M, et al. Diabetic autoimmune markers in children and adolescents with type 2 diabetes. Pediatrics. 2001;107(6). Available at: www.pediatrics.org/cgi/content/full/107/6/e102
    • (2001) Pediatrics , vol.107 , Issue.6
    • Hathout, E.H.1    Thomas, W.2    El-Shahaway, M.3
  • 41
    • 0042092541 scopus 로고    scopus 로고
    • What's in a name: Latent autoimmune diabetes of adults, type 1.5, adult-onset, and type 1 diabetes
    • Palmer JP, Hirsch IB. What's in a name: latent autoimmune diabetes of adults, type 1.5, adult-onset, and type 1 diabetes. Diabetes Care. 2003;26(2):536-538
    • (2003) Diabetes Care , vol.26 , Issue.2 , pp. 536-538
    • Palmer, J.P.1    Hirsch, I.B.2
  • 42
    • 27844507605 scopus 로고    scopus 로고
    • Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes
    • Gilliam LK, Brooks-Worrell BM, Palmer JP, Greenbaum CJ, Pihoker C. Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes. J Autoimmun. 2005;25(3):244-250
    • (2005) J Autoimmun , vol.25 , Issue.3 , pp. 244-250
    • Gilliam, L.K.1    Brooks-Worrell, B.M.2    Palmer, J.P.3    Greenbaum, C.J.4    Pihoker, C.5
  • 43
    • 0037711693 scopus 로고    scopus 로고
    • Coexistence of type 1 and type 2 diabetes: "double" diabetes
    • Libman IM, Becker DJ. Coexistence of type 1 and type 2 diabetes: "double" diabetes. Pediatr Diabetes. 2003;4(2):110-113
    • (2003) Pediatr Diabetes , vol.4 , Issue.2 , pp. 110-113
    • Libman, I.M.1    Becker, D.J.2
  • 44
    • 0141446269 scopus 로고    scopus 로고
    • Testing the accelerator hypothesis: The relationship between body mass and age at diagnosis of type 1 diabetes
    • Kibirige M, Metcalf B, Renuja R, Wilkin TJ. Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1 diabetes. Diabetes Care. 2003;26(10):2865-2870
    • (2003) Diabetes Care , vol.26 , Issue.10 , pp. 2865-2870
    • Kibirige, M.1    Metcalf, B.2    Renuja, R.3    Wilkin, T.J.4
  • 45
    • 0034932098 scopus 로고    scopus 로고
    • The accelerator hypothesis: Weight gain as the missing link between type I and type II diabetes
    • Wilkin TJ. The accelerator hypothesis: weight gain as the missing link between type I and type II diabetes. Diabetologia. 2001;44(7):914-922
    • (2001) Diabetologia , vol.44 , Issue.7 , pp. 914-922
    • Wilkin, T.J.1
  • 46
    • 0035985231 scopus 로고    scopus 로고
    • Insulin resistance in type 1 diabetes
    • Greenbaum CJ. Insulin resistance in type 1 diabetes. Diabetes Metab Res Rev. 2002;18(3):192-200
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.3 , pp. 192-200
    • Greenbaum, C.J.1
  • 48
    • 33646376936 scopus 로고    scopus 로고
    • Testing the accelerator hypothesis: Body size, beta-cell function, and age of onset of type 1 (autoimmune) diabetes
    • Dabelea D, D'Agostino RB Jr, Mayer-Davis EJ, et al. Testing the accelerator hypothesis: body size, beta-cell function, and age of onset of type 1 (autoimmune) diabetes. Diabetes Care. 2006;29(2):290-294
    • (2006) Diabetes Care , vol.29 , Issue.2 , pp. 290-294
    • Dabelea, D.1    D'Agostino Jr, R.B.2    Mayer-Davis, E.J.3
  • 49
    • 0027375768 scopus 로고
    • Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects: Evidence for a hyperbolic function
    • Kahn SE, Prigeon RL, McCulloch DK. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects: evidence for a hyperbolic function. Diabetes. 1993;42(11):1663-1672
    • (1993) Diabetes , vol.42 , Issue.11 , pp. 1663-1672
    • Kahn, S.E.1    Prigeon, R.L.2    McCulloch, D.K.3
  • 50
    • 0037768213 scopus 로고    scopus 로고
    • Metformin as an adjunct therapy in adolescents with type 1 diabetes and insulin resistance
    • Hamilton J, Cummings E, Zdravkovic V, Finegood D, Daneman D. Metformin as an adjunct therapy in adolescents with type 1 diabetes and insulin resistance. Diabetes Care. 2003;26(1):138-143
    • (2003) Diabetes Care , vol.26 , Issue.1 , pp. 138-143
    • Hamilton, J.1    Cummings, E.2    Zdravkovic, V.3    Finegood, D.4    Daneman, D.5
  • 51
    • 0142154262 scopus 로고    scopus 로고
    • Metformin as additional therapy in adolescents with poorly controlled type 1 diabetes: Randomized placebo-controlled trial with aspects on insulin sensitivity
    • Särnblad S, Kroon M, Åman J. Metformin as additional therapy in adolescents with poorly controlled type 1 diabetes: randomized placebo-controlled trial with aspects on insulin sensitivity. Eur J Endocrinol. 2003;149(4):323-329
    • (2003) Eur J Endocrinol , vol.149 , Issue.4 , pp. 323-329
    • Särnblad, S.1    Kroon, M.2    Åman, J.3
  • 52
    • 0021204137 scopus 로고
    • Evidence that metformin addition to insulin induces an amelioration of glycaemic profile in type 1 (insulin-dependent) diabetes mellitus
    • Coscelli C, Palmari V, Saccardi F, Alpi O, Bonora E. Evidence that metformin addition to insulin induces an amelioration of glycaemic profile in type 1 (insulin-dependent) diabetes mellitus. Curr Ther Res. 1984;35(6):1058-1064
    • (1984) Curr Ther Res , vol.35 , Issue.6 , pp. 1058-1064
    • Coscelli, C.1    Palmari, V.2    Saccardi, F.3    Alpi, O.4    Bonora, E.5
  • 53
    • 0025952139 scopus 로고
    • Effects of metformin on haemorheology, lipid parameters and insulin resistance in insulin-dependent diabetic patients (IDDM)
    • Janssen M, Rillaerts E, De Leeuw I. Effects of metformin on haemorheology, lipid parameters and insulin resistance in insulin-dependent diabetic patients (IDDM). Biomed Pharmacother. 1991;45(8):363-367
    • (1991) Biomed Pharmacother , vol.45 , Issue.8 , pp. 363-367
    • Janssen, M.1    Rillaerts, E.2    De Leeuw, I.3
  • 54
    • 21544439039 scopus 로고    scopus 로고
    • The effect of rosiglitazone on overweight subjects with type 1 diabetes
    • Strowig SM, Raskin P. The effect of rosiglitazone on overweight subjects with type 1 diabetes. Diabetes Care. 2005;28(7):1562-1567
    • (2005) Diabetes Care , vol.28 , Issue.7 , pp. 1562-1567
    • Strowig, S.M.1    Raskin, P.2
  • 55
    • 33751415019 scopus 로고    scopus 로고
    • Pioglitazone as adjunctive therapy in adolescents with type 1 diabetes
    • Zdravkovic V, Hamilton JK, Daneman D, Cummings EA. Pioglitazone as adjunctive therapy in adolescents with type 1 diabetes. J Pediatr. 2006;149(6):845-849
    • (2006) J Pediatr , vol.149 , Issue.6 , pp. 845-849
    • Zdravkovic, V.1    Hamilton, J.K.2    Daneman, D.3    Cummings, E.A.4
  • 56
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356(24):2457-2471
    • (2007) N Engl J Med , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 57
    • 33748748473 scopus 로고    scopus 로고
    • Thiazolidinedione use and bone loss in older diabetic patients
    • Schwartz AV, Sellmeyer DE, Vittinghoff E, et al. Thiazolidinedione use and bone loss in older diabetic patients. J Clin Endocrinol Metab. 2006;91(9):3349-3354
    • (2006) J Clin Endocrinol Metab , vol.91 , Issue.9 , pp. 3349-3354
    • Schwartz, A.V.1    Sellmeyer, D.E.2    Vittinghoff, E.3
  • 58
    • 33746686369 scopus 로고    scopus 로고
    • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
    • Pearson ER, Flechtner I, Njolstad PR, et al. Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations. N Engl J Med. 2006;355(5):467-477
    • (2006) N Engl J Med , vol.355 , Issue.5 , pp. 467-477
    • Pearson, E.R.1    Flechtner, I.2    Njolstad, P.R.3
  • 59
    • 0842285626 scopus 로고    scopus 로고
    • Mitochondrial diabetes: Molecular mechanisms and clinical presentation
    • Maassen JA, 'T Hart LM, van Essen E, et al. Mitochondrial diabetes: molecular mechanisms and clinical presentation. Diabetes. 2004;53(suppl 1):S103-S109
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Maassen, J.A.1    'T Hart, L.M.2    van Essen, E.3
  • 60
    • 4244195170 scopus 로고    scopus 로고
    • Basal and post prandial C-peptide values in a racially mixed population of adolescents with type 2 diabetes mellitus
    • Clemons D, Gottschalk ME, Jones KL. Basal and post prandial C-peptide values in a racially mixed population of adolescents with type 2 diabetes mellitus. Diabetes. 1999;48(suppl 1):80A
    • (1999) Diabetes , vol.48 , Issue.SUPPL. 1
    • Clemons, D.1    Gottschalk, M.E.2    Jones, K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.