Tryptophan mutants of cardiac troponin C: 3D structure, troponin I affinity, and in situ activity

Biochemistry

Volumn 47, Issue 2, 2008, Pages 597-606

  Julien, Olivier ^a   Sun, Yin Biao ^b   Wang, Xu ^a   Lindhout, Darrin A ^a   Thiessen, Angela ^a   Irving, Malcolm ^b   Sykes, Brian D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SKELETAL MUSCLE FIBERS; TRYPTOPHAN MUTANTS;

BIOPHYSICS; FLUORESCENCE SPECTROSCOPY; MUSCLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS;

CARBON;

5 HYDROXYTRYPTOPHAN; CALCIUM; FLUORINE DERIVATIVE; FLUOROTRYPTOPHAN; INDOLE; MUTANT PROTEIN; TROPONIN C; TROPONIN I; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; FLUORESCENCE SPECTROSCOPY; MEASUREMENT; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SKELETAL MUSCLE; WILD TYPE;

ANIMALS; CALCIUM; DIMERIZATION; HUMANS; MODELS, MOLECULAR; MUSCLE FIBERS; MUSCLE, SKELETAL; MUTANT PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RABBITS; TITRIMETRY; TRIFLUOROETHANOL; TROPONIN C; TROPONIN I; TRYPTOPHAN;

EID: 38849099005     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi702056g     Document Type: Article

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