Classical swine fever virus E2 glycoprotein antigen produced in adenovirally transduced PK-15 cells confers complete protection in pigs upon viral challenge

Vaccine

Volumn 26, Issue 7, 2008, Pages 988-997

  Sánchez, Oliberto ^a   Barrera, Maritza ^b   Rodríguez, María P ^a   Frías, María T ^b   Figueroa, Nancy E ^a   Naranjo, Paula ^d   Montesino, Raquel ^a   Farnos, Omar ^a   Castell, Sara ^b   Venereo, Alina ^a   Ganges, Llilianne ^c   Borroto, Carlos ^a   Toledo, Jorge R ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

^b National Centre for Animal and Plant Health CENSA   (Cuba)

^c INIA   (Spain)

^d Medicine Veterinary Institute   (Cuba)

Author keywords

Adenovirus; Classical swine fever; E2 glycoprotein; Protein production system; Veterinary vaccine

Indexed keywords

ADENOVIRUS VECTOR; AGAROSE; FREUND ADJUVANT; GLYCOPROTEIN E2; HISTIDINE; HOMODIMER; IMIDAZOLE; LECTIN; NEUTRALIZING ANTIBODY; NICKEL; OLIGOSACCHARIDE; RECOMBINANT ANTIGEN; SIGNAL PEPTIDE;

3' UNTRANSLATED REGION; ADENOVIRUS; AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DISULFIDE BOND; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; KIDNEY EPITHELIUM; LYMPHOCYTE; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PESTIVIRUS; PRIORITY JOURNAL; PROTEIN DOMAIN; SWINE; VACCINATION; VIRUS DETECTION; VIRUS INFECTION; VIRUS ISOLATION; VIRUS STRAIN;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, VIRAL; CELLS, CULTURED; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; KIDNEY; SWINE; TRANSDUCTION, GENETIC; VACCINATION; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

EID: 38749132303     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.11.014     Document Type: Article

References (43)

1. Moennig V., Floegel-Niesmann G., and Greiser-Wilke I. Clinical signs and epidemiology of classical swine fever: a review of new knowledge. Vet J 165 (2003) 11-20
2. Moennig V. Classical swine fever and related viral infections. In: Liess B. (Ed). Characteristics of the virus (1988), Martinus Nijhoff Publishers, Boston, Mass 55-88
3. van Regenmortel M.H.V., Fauquet C.M., Bishop D.H.L., Carstens E.B., Estes M.K., Lemon S.M., et al. Virus taxonomy. Seventh report of the international committee on taxonomy of viruses (2000), Academic Press, San Diego, CA
4. Rümenapf T., Unger G., Strauss J.H., and Thiel H.J. Processing of the envelope glycoproteins of pestiviruses. J Virol 67 (1993) 3288-3294
5. Weiland E., Stark R., Hass B., Rumenapf T., Meyers G., and Thiel H.-J. Pestivirus glycoprotein which induces neutralizing antibodies forms part of a disulfide-linked heterodimer. J Virol 64 (1990) 3563-3569
6. Rumenapf T., Stark R., Meyers G., and Thiel H.-J. Structural proteins of hog cholera virus expressed by vaccinia virus: further characterization and induction of protective immunity. J Virol 65 (1991) 589-597
7. Van Rijn P.A., Bossers A., Wensvoort G., and Moormann R.J. Classical swine fever virus (CSFV) envelope glycoprotein E2 containing one structural antigenic unit protects pigs from lethal CSFV challenge. J Gen Virol 77 (1996) 2737-2745
8. Weiland E., Ahl R., Stark R., Weiland F., and Thiel H.-J. A second envelope glycoprotein mediates neutralization of a pestivirus, hog cholera virus. J Virol 66 (1992) 3677-3682
9. Terpstra C., Woortmeyer R., and Barteling S.J. Development and properties of a cell culture produced vaccine for hog cholera based on the Chinese strain. DTW Dtsch Tierarztl Wochenschr 97 (1990) 77-79
10. Dahle J., and Liess B. Assessment of safety and protective value of a cell culture modified strain "C" vaccine of hog cholera/classical swine fever virus. Berl Munch Tierartzl Wschr 108 (1995) 20-25
11. Council Directive 80/217/EEC. Introducing community measures for the control of classical swine fever. VI/5429/94, 22 January 1980.
12. van Gennip H.G., Bouma A., van Rijn P.A., Widjojoatmodjo M.N., and Moormann R.J. Experimental non-transmissible marker vaccines for classical swine fever (CSF) by trans-complementation of Erns or E2 of CSFV. Vaccine 20 (2002) 1544-1556
13. Greiser-Wilke I., and Moennig V. Vaccination against classical swine fever virus: limitations and new strategies. Anim Health Res Rev 5 (2004) 223-226
14. Dong X.N., Wei K., Liu Z.Q., and Chen Y.H. Candidate peptide vaccine induced protection against classical swine fever virus. Vaccine 13 (2002) 167-173
15. Yu X., Tu C., Li H., Hu R., Chen C., Li Z., et al. DNA-mediated protection against classical swine fever virus. Vaccine 19 (2001) 1520-1525
16. de Smit A.J., Bouma A., van Gennip E.P., de Kluijver E.P., and Moormann R.J. Chimeric (marker) C-strain viruses induce clinical protection against virulent classical swine fever virus (CSFV) and reduce transmission of CSFV between vaccinated pigs. Vaccine 19 (2001) 1467-1476
17. Hahn J., Park S.H., Song J.Y., An S.H., and Ahn B.Y. Construction of recombinant swinepox viruses and expression of the classical swine fever virus E2 protein. J Virol Methods 93 (2001) 49-56
18. van Rijn P.A., van Gennip H.G., and Moormann R.J. An experimental marker vaccine and accompanying serological diagnostic test both based on envelope glycoprotein E2 of classical swine fever (CSFV). Vaccine 17 (1999) 433-440
19. Moormann R.J., Bouma A., Kramps J.A., Terpstra C., and de Smit H.J. Development of a classical swine fever subunit marker vaccine and companion diagnostic test. Vet Microbiol 73 (2000) 209-219
20. Dewulf J., Laevens H., Koenen F., Mintiens K., and de Kruif A. An E2 sub-unit marker vaccine does not prevent horizontal or vertical transmission of classical swine fever virus. Vaccine 20 (2001) 86-91
21. Hulst M.M., Westra D.F., Wensvoort G., and Moormann R.J. Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera. J Virol 67 (1993) 5435-5442
22. van Oers M.M., Thomas A.A., Moormann R.J., and Vlak J.M. Secretory pathway limits the enhanced expression of classical swine fever virus E2 glycoprotein in insect cells. J Biotech 86 (2001) 31-38
23. Graham F.L., Smiley J., Russel W.C., and Nairn R. Characteristics of a human cell line transformed by DNA from human adenovirus 5. J Gen Virol 36 (1977) 59-72
24. Wensvoort G., Terpstra C., Boonstra J., Bloemraad M., and Van Zaane D. Production of monoclonal antibodies against swine fever virus and their use in laboratory diagnosis. Vet Microbiol 12 (1986) 101-108
25. Diaz de Arce H., Nunez J.I., Ganges L., Barreras M., Teresa Frias M., and Sobrino F. Molecular epidemiology of classical swine fever in Cuba. Virus Res 64 (1999) 61-67
26. de Arce H.D., Ganges L., Barrera M., Naranjo D., Sobrino F., Frias M.T., et al. Origin and evolution of viruses causing classical swine fever in Cuba. Virus Res 112 (2005) 123-131
27. Ganges L., Barrera M., Nunez J.I., Blanco I., Frias M.T., Rodríguez F., et al. A DNA vaccine expressing the E2 protein of classical swine fever virus elicits T cell responses that can prime for rapid antibody production and confer total protection upon viral challenge. Vaccine 23 (2005) 3741-3752
28. Herrera A.M., Rodriguez E.G., Hernandez T., Sandez B., and Duarte C.A. A family of compact plasmid vectors for DNA immunization in humans. Biochem Biophys Res Commun 279 (2000) 548-551
29. He T.C., Zhou S., da Costa L.T., Yu J., Kinzler K.W., and Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95 (1998) 2509-2514
30. OIE. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004, consulted october 30/2006: http://www.oie.int/eng/normes/mmanual/A_00036.htm; 2004.
31. Dong X.N., and Chen Y.H. Marker vaccine strategies and candidate CSFV marker vaccines. Vaccine 25 (2006) 205-230
32. Jarvis D.L. Baculovirus expression vectors. In: Miller L.K. (Ed). The baculoviruses (1997), Plenum Press, New York 389-431
33. Sanchez O., Toledo J.R., Rodriguez M.P., and Castro F.O. Adenoviral vector mediates high expression levels of human growth hormone in the milk of mice and goats. J Biotech 114 (2004) 89-97
34. Toledo J.R., Sánchez O., Montesino R., García G., Montañez M., Zamora P.A., et al. High expression level of recombinant human erythropoietin in the milk of non-transgenic goats. J Biotech 123 (2006) 225-235
35. Thiel H.-J., Stark R., Weiland E., Rümenapf T., and Meyers G. Hog cholera virus: molecular composition of virions from a pestivirus. J Virol 65 (1991) 4705-4712
36. Huang Y., Mechref Y., and Novotny M.V. N-linked oligosaccharide structures in the diamine oxidase from porcine kidney. Carbohydr Res 323 (2000) 111-125
37. Hooker A.D., Green N.H., Baines A.J., Bull A.T., Jenkins N., Strange P.G., et al. Constraints on the transport and glycosylation of recombinant IFN-gamma in Chinese hamster ovary and insect cells. Biotechnol Bioeng 63 (1999) 559-572
38. Tomiya N., Ailor E., Lawrence S.M., Betenbaugh M.J., and Lee Y.C. Determination of nucleotides and sugar nucleotides involved in protein glycosylation by high-performance anion-exchange chromatography: sugar nucleotide contents in cultured insect cells and mammalian cells. Anal Biochem 293 (2001) 129-137
39. Marchal I., Jarvis D.L., Cacan R., and Verbert A. Glycoproteins from insect cells: sialylated or not?. Biol Chem 382 (2001) 151-159
40. Risatti G.R., Holinka L.G., Fernandez Sainz I., Carrillo C., Lu Z., and Borca M.V. N-linked glycosylation status of classical swine fever virus strain Brescia E2 glycoprotein influences virulence in swine. J Virol 81 (2007) 924-933
41. Hulst M.M., and Moormann R.J. Inhibition of pestivirus infection in cell culture by envelope proteins E(rns) and E2 of classical swine fever virus: E(rns) and E2 interact with different receptors. J Gen Virol 78 (1997) 2779-2787
42. Precausta P., Kato F., and Brun A. Swine fever. Immunisation of piglets. Comp Immunol Microbiol Infect Dis 6 (1983) 281-289
43. Ganges L., Núñez J.I., Sobrino F., Borrego B., Fernández-Borges N., Frías-Lepoureau M.T., et al. Recent advances in the development of recombinant vaccines against classical swine fever virus: cellular responses also play a role in protection. Vet J (2007) [Epub ahead of print]