Impact of coexistent schizotypal personality traits on frontal lobe function in obsessive-compulsive disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 32, Issue 2, 2008, Pages 472-478

  Shin, Na Young ^a   Lee, Ae Ra ^a   Park, Hye Yoon ^b   Yoo, So Young ^a,b   Kang, Do Hyung ^a,b   Shin, Min Sup ^b   Kwon, Jun Soo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

Author keywords

Frontal lobe function; Obsessive compulsive disorder; Schizotypal personality traits

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR;

ADULT; APTITUDE TEST; ARTICLE; BRAIN FUNCTION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; OBSESSIVE COMPULSIVE DISORDER; POST HOC ANALYSIS; PREFRONTAL CORTEX; QUESTIONNAIRE; SCHIZOTYPAL PERSONALITY DISORDER; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; WISCONSIN CARD SORTING TEST;

ADULT; AGE FACTORS; COMORBIDITY; CONTROL GROUPS; EDUCATIONAL STATUS; FEMALE; FRONTAL LOBE; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; OBSESSIVE-COMPULSIVE DISORDER; SCHIZOTYPAL PERSONALITY DISORDER; SEX FACTORS; SPEECH DISORDERS;

EID: 38749094878     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2007.09.020     Document Type: Article

References (59)

1. American psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed (1994), American Psychiatric Association, Washington, DC
2. Abbruzzese M., Ferri S., and Scarone S. Wisconsin Card Sorting Test performance in obsessive-compulsive disorder: no evidence for involvement of dorsolateral prefrontal cortex. Psychiatry Res 58 (1995) 37-43
3. Abbruzzese M., Ferri S., and Scarone S. The selective breakdown of frontal functions in patients with obsessive-compulsive disorder and in patients with schizophrenia: a double dissociation experimental finding. Neuropsychologia 35 (1997) 907-912
4. Aycicegi A., Dinn W.M., Harris C.L., and Erkmen H. Neuropsychological function in obsessive-compulsive disorder: effects of comorbid conditions on task performance. Eur Psychiatry 18 (2003) 241-248
5. Basso M.R., Bornstein R.A., Carona F., and Morton R. Depression accounts for executive function deficits in obsessive-compulsive disorder. Neuropsychiatry Neuropsychol Behav Neurol 14 (2001) 241-245
6. Baxter L.R., Schwartz J.M., Mazziotta J.C., Phelps M.E., Pahl J.J., Guze B.H., et al. Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder. Am J Psychiatry 145 (1988) 1560-1563
7. Benton A.L. Development of a multilingual aphasia battery: progress and problems. J Neurol Sci 9 (1969) 39-48
8. Bergman A.J., Harvey P.D., Roitman S.L., Mohs R.C., Marder D., Silverman J.M., et al. Verbal learning and memory in schizotypal personality disorder. Schizophr Bull 24 (1998) 635-641
9. Cavedini P., Ferri S., Scarone S., and Bellodi L. Frontal lobe dysfunction in obsessive-compulsive disorder and major depression: a clinical-neuropsychological study. Psychiatry Res 78 (1998) 21-28
10. Choi J.S., Kang D.H., Kim J.J., Ha T.H., Lee J.M., Youn T., et al. Left anterior subregion of orbitofrontal cortex volume reduction and impaired organizational strategies in obsessive-compulsive disorder. J Psychiatric Res 38 (2004) 193-199
11. Christensen K.J., Kim S.W., Dysken M.W., and Maxwell H.K. Neuropyschological performance in obsessive-compulsive disorder. Biol Psychiatry 31 (1992) 4-18
12. Cox C.S. Neuropsychological abnormalities in obsessive-compulsive disorder and their assessments. Int Rev Psychiatry 9 (1997) 45-60
13. Crespo-Facorro B., Cabranes J.A., Lopez-Ibor Alcocer M.I., Paya B., Perez C.F., Encinas M., et al. Regional cerebral blood flow in obsessive-compulsive patients with and without a chronic tic disorder: a SPECT study. Eur Arch Psychiatry Clin Neurosci 249 (1999) 156-161
14. Daban C., Amado I., Bourdel M.C., Loo H., Olie J.P., Poirier M.F., et al. Cognitive dysfunctions in medicated and unmedicated patients with recent-onset schizophrenia. J Psychiatric Res 39 (2005) 391-398
15. Demakis G.J. A meta-analytic review of the sensitivity of the Wisconsin Card Sorting test to frontal and lateralized frontal brain damage. Neuropsychology 17 (2003) 255-264
16. Dickey C.C., McCarley R.W., Niznikiewicz M.A., Voglmaier M.M., Seidman L.J., Kim S., et al. Clinical, cognitive, and social characteristics of a sample of neuroleptic-naive persons with schizotypal personality disorder. Schizophr Res 78 (2005) 297-308
17. Fenger M.M., Gade A., Adams K.H., Hansen E.S., Bolwig T.G., and Knudsen G.M. Cognitive deficits in obsessive-compulsive disorder on tests of frontal lobe functions. Nordic J Psychiatry 59 (2005) 39-44
18. First M.B., Spitzer R.L., Gibbson M., and Williams J.B.W. Structured clinical interview for DSM-IV Axis I disorder (1996), New York State Psychiatric Institute, New York
19. Frare F., Perugi G., Ruffolo G., and Toni C. Obsessive-compulsive disorder and body dysmorphic disorder: a comparison of clinical features. Eur Psychiatry 19 (2004) 292-298
20. Frith C.D., Friston K.J., Liddle P.F., and Frackowiak R.S.J. A PET study of word finding. Neuropsychologia 29 (1991) 1137-1148
21. Goodman W.K., Price L.H., Rasmussen S.A., Mazure C., Delgado P., Heninger G.R., et al. The Yale-Brown Obsessive Compulsive Scale. II. Validity. Arch Gen Psychiatry 46 (1989) 1012-1016
22. Gross-Isseroff R., Sasson Y., Voet H., Hendler T., Luca-Haimovici K., Kandel-Sussman H., et al. Alternation learning in obsessive-compulsive disorder. Biol Psychiatry 39 (1996) 733-738
23. Harris C.L., and Dinn W.M. Subtyping obsessive-compulsive disorder: Neuropsychological correlates. Behav Neurol 14 (2003) 75-87
24. Harvey P.D., and Keefe R.S. Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment. Am J Psychiatry 158 (2001) 176-184
25. Heaton R.K., Chelune G.J., Talley J.L., Kay G.G., and Curtiss G. Wisconsin Card Sorting Test manual: revised and expanded (1993), Psycological Assessment Resources, Odessa, Flourida
26. Hyler S.E. Personality diagnosis questionnaire-IV (1998), New York State Psychiatric Institute, New York
27. Hyler S.E., Skodol A.E., Kellman H.D., Oldham J.M., and Rosnick L. Validity of the Personality Diagnostic Questionnaire-revised: comparison with two structured interviews. Am J Psychiatry 147 (1990) 1043-1048
28. Jenike M.A., Baer L., Minichiello W.E., Schwartz C.E., and Carey Jr. R.J. Concomitant obsessive-compulsive disorder and schizotypal personality disorder. Am J Psychiatry 143 (1986) 530-532
29. Kang Y.W., Chin J.H., Na D.L., and Lee J.H. A normative study of the Korean version of the Controlled Oral Word Association Test (COWAT) in the elderly. Korean J Clin Psychol 19 (2000) 385-392
30. Kay S.R., Fiszbein A., and Opler L.A. The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophr Bull 13 (1987) 261-276
31. Keefe R.S., Silverman J.M., Lees Roitman S.E., Harvey P.D., Duncan M.A., Alroy D., et al. Performance of nonpsychotic relatives of schizophrenic patients on cognitive tests. Psychiatry Res 53 (1994) 1-12
32. Kertesz A. Western Aphasia Battery (1980), The Psychological Corporation, San Antonio, TX
33. Kim D.I., Choi M.R., and Cho E.C. The preliminary study of reliabilitiy and validity on the Korean version of personality disorder questionnaire-4+(PDQ-4+). J Korean Neuropsychiatr Assoc 39 (2000) 525-538
34. Kim M.S., Kang S.S., Youn T., Kang D.H., Kim J.J., and Kwon J.S. Neuropsychological correlates of P300 abnormalities in patients with schizophrenia and obsessive-compulsive disorder. Psychiatry Res: Neuroimaging 123 (2003) 109-123
35. Kitis A., Akdede B.B.K., Alptekin K., Akvardar Y., Arkar H., Erol A., et al. Cognitive dysfunctions in patients with obsessive-compulsive disorder compared to the patients with schizophrenia patients: relation to overvalued ideas. Prog Neuro-Psychopharmacol Biol Psychiatry 31 (2007) 254-261
36. Klein D., Milner B., Zatorre R.J., Meyer E., and Evans A.C. The neural substrates underlying word generation: a bilingual functional-imaging study. Proc Natl Acad Sci U S A 92 (1995) 2899-2903
37. Kuelz A.K., Hohagen F., and Voderholzer U. Neuropsychological performance in obsessive-compulsive disorder: a critical review. Biol Psychol 65 (2004) 185-236
38. Leckman J.F., Grice D.E., Boardman J., Zhang H., Vitale A., Bondi C., et al. Symptoms of obsessive-compulsive disorder. Am J Psychiatry 154 (1997) 911-917
39. Lee K.J., Shin Y.W., Wee H., Kim Y.Y., and Kwon J.S. Gray matter volume reduction in obsessive-compulsive disorder with schizotypal personality trait. Prog Neuropsychopharmacol Biol Psychiatry 30 (2006) 1146-1149
40. Lenzenweger M.F., and Korfine L. Perceptual aberrations, schizotypy, and the Wisconsin Card Sorting Test. Schizophr Bull 20 (1994) 345-357
41. Martinot J.L., Allilaire J.F., Mazoyer B.M., Hantouche E., Huret J.D., Legaut-Demare F., et al. Obsessive-compulsive disorder: a clinical, neuropsychological and positron emission tomography study. Acta Psychiatr Scand 82 (1990) 233-242
42. Mattis S. Mattis Dementia rating scale (1988), Psychological Assessment Resources, Odessa, Fourida
43. Milner B. Effects of different brain lesions on card sorting: the role of frontal lobes. Arch Neurol 9 (1963) 90-100
44. Moore D.J., Savla G.N., Woods S.P., Jeste D.V., and Palmer B.W. Verbal fluency impairments among middle-aged and older outpatients with schizophrenia are characterized by deficient switching. Schizophr Res 87 (2006) 254-260
45. Moritz S., Birkner C., Kloss M., Jacobsen D., Fricke S., Bothern A., et al. Impact of comorbid depressive symptoms on neuropsychological performance in obsessive-compulsive disorder. J Abnorm Psychol 110 (2001) 653-657
46. Moritz S., Jacobsen D., Kloss M., Fricke S., Rufer M., and Hand I. Examination of emotional Stroop interference in obsessive-compulsive disorder. Behav Res Ther 42 (2004) 671-682
47. Okasha A., Rafaat M., Mahallawy N., El Nahas G., El Dawla A.S., Sayed M., et al. Cognitive dysfunction in obsessive-compulsive disorder. Acta Psychiatr Scand 101 (2000) 281-285
48. Poyurovsky M., and Koran L.M. Obsessive-compulsive disorder (OCD) with schizotypy vs. schizophrenia with OCD: diagnostic dilemmas and therapeutic implications. J Psychiatr Res 39 (2005) 399-408
49. Raine A., Sheard C., Reynolds G.P., and Lencz T. Pre-frontal structural and functional deficits associated with individual differences in schizotypal personality. Schizophr Res 7 (1992) 237-247
50. Saxena S., Brody A.L., Maidment K.M., Dunkin J.J., Colgan M., Alborzian S., et al. Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive-compulsive disorder. Neuropsychopharmacology 21 (1999) 683-693
51. Schmidtke K., Schorb A., Winkelmann G., and Hohagen F. Cognitive frontal lobe dysfunction in obsessive-compulsive disorder. Biol Psychiatry 43 (1998) 666-673
52. Sobin C., Blundell M.L., Weiller F., Gavigan C., Haiman C., and Karayiorgou M. Evidence of a schizotypy subtype in OCD. J Psychiatr Res 34 (2000) 15-24
53. Stuss D.T., Levine B., Alexander M.P., Hong J., Palumbo C., Hamer L., et al. Wisconsin Card Sorting Test performance in patients with focal frontal and posterior brain damage: effects of lesion location and test structure on separable cognitive processes. Neuropsychologia 38 (2000) 388-402
54. Szeszko P.R., Robinson D., Alvir J.M., Bilder R.M., Lencz T., Ashtari M., et al. Orbital frontal and amygdala volume reductions in obsessive-compulsive disorder. Arch Gen Psychiatry 56 (1999) 913-919
55. Trestman R.L., Keefe R.S., Mitropoulou V., Harvey P.D., deVegvar M.L., Lees-Roitman S., et al. Cognitive function and biological correlates of cognitive performance in schizotypal personality disorder. Psychiatry Res 59 (1995) 127-136
56. Troyer A.K., Moscovitch M., and Winocur G. Clustering and switching as two components of verbal fluency: evidence from younger and older healthy adults. Neuropsychology 11 (1997) 138-146
57. Voglmaier M.M., Seidman L.J., Salisbury D., and McCarley R.W. Neuropsychological dysfunction in schizotypal personality disorder: a profile analysis. Biol Psychiatry 41 (1997) 530-540
58. Warner M.B., Morey L.C., Finch J.F., Gunderson J.G., Skodol A.E., Sanislow C.A., et al. The longitudinal relationship of personality traits and disorders. J Abnorm Psychol 113 (2004) 217-227
59. Yi J.S., Ahn Y.M., Shin H.K., An S.K., Joo Y.H., Kim S.H., et al. Reliability and validity of the Korean version of the Positive and Negative Syndrome Scale. J Korean Neuropsychiatr Assoc 40 (2001) 1090-1105