Hormone therapy is associated with preserved smooth muscle structure and dilation in the arterial vasculature of the leg in older women

Maturitas

Volumn 59, Issue 1, 2008, Pages 46-54

  Parker, Beth A ^a   Smithmyer, Sandra L ^a   Proctor, David N ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Age; Estrogen; Intima medial thickness; Popliteal artery

Indexed keywords

CONJUGATED ESTROGEN; CONJUGATED ESTROGEN PLUS MEDROXYPROGESTERONE ACETATE; ESTRADIOL; GLYCERYL TRINITRATE; PROGESTERONE;

ADULT; AGE DISTRIBUTION; AGED; ARTERY DILATATION; ARTERY INTIMA; ARTERY MEDIA; ARTICLE; CONTROLLED STUDY; DOPPLER FLOWMETRY; DRUG EFFECT; FEMALE; HORMONE SUBSTITUTION; HUMAN; LEG BLOOD FLOW; NORMAL HUMAN; POPLITEAL ARTERY; PULSE WAVE; SMOOTH MUSCLE;

ADULT; AGE FACTORS; AGED; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; MIDDLE AGED; MUSCLE, SMOOTH; NITROGLYCERIN; POPLITEAL ARTERY; TUNICA INTIMA; TUNICA MEDIA; ULTRASONOGRAPHY, DOPPLER; VASODILATION; VASODILATOR AGENTS;

EID: 38749094417     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2007.10.009     Document Type: Article

References (47)

1. Dinenno F.A., Jones P.P., Seals D.R., and Tanaka H. Age-associated arterial wall thickening is related to elevations in sympathetic activity in healthy humans. Am J Physiol Heart Circ Physiol 278 (2000) H1205-H1210
2. Moreau K.L., Donato A.J., Seals D.R., et al. Arterial intima-media thickness: site-specific associations with HRT and habitual exercise. Am J Physiol Heart Circ Physiol 283 (2002) H1409-H1417
3. Poredos P., Kek A., and Verhovec R. Morphological and functional changes of the arterial wall in subjects at risk of atherosclerosis and in patients with peripheral arterial occlusive disease. Vasa 26 (1997) 271-276
4. Cheng K.S., Mikhailidis D.P., Hamilton G., and Seifalian A.M. A review of the carotid and femoral intima-media thickness as an indicator of the presence of peripheral vascular disease and cardiovascular risk factors. Cardiovasc Res 54 (2002) 528-538
5. Higgins J.P., and Higgins J.A. Epidemiology of peripheral arterial disease in women. J Epidemiol 13 (2003) 1-14
6. Schnaper H.W., McGuire J., Runyan C., and Hubchak S.C. Sex steroids and the endothelium. Curr Med Chem 7 (2000) 519-531
7. Dobs A.S., Nieto F.J., Szklo M., Barnes R., Sharrett A.R., and Ko W.J. Risk factors for popliteal and carotid wall thicknesses in the atherosclerosis risk in communities (ARIC) study. Am J Epidemiol 150 (1999) 1055-1067
8. Szilagyi D.E., Schwartz R.L., and Reddy D.J. Popliteal arterial aneurysms. Their natural history and management. Arch Surg 116 (1981) 724-728
9. Tohno S., and Tohno Y. Age-related differences in calcium accumulation in human arteries. Cell Mol Biol (Noisy-le-grand) 44 (1998) 1253-1263
10. Wensing P.J., Scholten F.G., Buijs P.C., Hartkamp M.J., Mali W.P., and Hillen B. Arterial tortuosity in the femoropopliteal region during knee flexion: a magnetic resonance angiographic study. J Anat 187 Pt 1 (1995) 133-139
11. Debasso R., Astrand H., Bjarnegard N., Ryden Ahlgren A., Sandgren T., and Lanne T. The popliteal artery, an unusual muscular artery with wall properties similar to the aorta: implications for susceptibility to aneurysm formation?. J Vasc Surg 39 (2004) 836-842
12. Sanada H., Higashi Y., Goto C., Chayama K., Yoshizumi M., and Sueda T. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities. Atherosclerosis 178 (2005) 179-185
13. Lau T.K., Wan D., Yim S.F., Sanderson J.E., and Haines C.J. Prospective, randomized, controlled study of the effect of hormone-replacement therapy on peripheral blood flow velocity in postmenopausal women. Fertil Steril 70 (1998) 284-288
14. Parker B.A., Smithmyer S.L., Jarvis S.S., Ridout S.J., Pawelczyk J.A., and Proctor D.N. Evidence for reduced sympatholysis in leg resistance vasculature of healthy older women. Am J Physiol Heart Circ Physiol 292 (2007) H1148-H1156
15. Parker B.A., Ridout S.J., and Proctor D.N. Age and flow-mediated dilation: a comparison of dilatory responsiveness in the brachial and popliteal arteries. Am J Physiol Heart Circ Physiol 291 (2006) H3043-H3049
16. Dinenno F.A., Tanaka H., Monahan K.D., et al. Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men. J Physiol 534 (2001) 287-295
17. Astrand H., Ryden-Ahlgren A., Sandgren T., and Lanne T. Age-related increase in wall stress of the human abdominal aorta: an in vivo study. J Vasc Surg 42 (2005) 926-931
18. Grodstein F., Manson J.E., and Stampfer M.J. Hormone therapy and coronary heart disease: the role of time since menopause and age at hormone initiation. J Womens Health (Larchmt) 15 (2006) 35-44
19. Rossouw J.E., Prentice R.L., Manson J.E., et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 297 (2007) 1465-1477
20. Sherwood A., Bower J.K., McFetridge-Durdle J., Blumenthal J.A., Newby L.K., and Hinderliter A.L. Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women. Arterioscler Thromb Vasc Biol 27 (2007) 1782-1787
21. ACSM. ACSM's guidelines for exercise testing and prescription. 6th ed. (2006), Lippincott Williams and Wilkins, Philadelphia
22. Dipietro L., Caspersen C.J., Ostfeld A.M., and Nadel E.R. A survey for assessing physical activity among older adults. Med Sci Sports Exerc 25 (1993) 628-642
23. Baecke J.A., Burema J., and Frijters J.E. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 36 (1982) 936-942
24. 2 during peak cycle exercise in younger and older women. Med Sci Sports Exerc 36 (2004) 623-631
25. Cortez-Cooper M.Y., Supak J.A., and Tanaka H. A new device for automatic measurements of arterial stiffness and ankle-brachial index. Am J Cardiol 91 (2003) 1519-1522 A9
26. Proctor D.N., Le K.U., and Ridout S.J. Age and regional specificity of peak limb vascular conductance in men. J Appl Physiol 98 (2005) 193-202
27. Webster J.G. Medical instrumentation: application and design. 3RD 98 ed. (1998), John Wiley and Sons, New York
28. Pignoli P., Tremoli E., Poli A., Oreste P., and Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation 74 (1986) 1399-1406
29. Moreau K.L., Silver A.E., Dinenno F.A., and Seals D.R. Habitual aerobic exercise is associated with smaller femoral artery intima-media thickness with age in healthy men and women. Eur J Cardiovasc Prev Rehabil 13 (2006) 805-811
30. Bonithon-Kopp C., Touboul P.J., Berr C., Magne C., and Ducimetiere P. Factors of carotid arterial enlargement in a population aged 59-71 years: the EVA study. Stroke 27 (1996) 654-660
31. Crouse J.R., Goldbourt U., Evans G., et al. Arterial enlargement in the atherosclerosis risk in communities (ARIC) cohort. In vivo quantification of carotid arterial enlargement. The ARIC Investigators. Stroke 25 (1994) 1354-1359
32. Cronenwett J.L. Variables that affect the expansion rate and rupture of abdominal aortic aneurysms. Ann N Y Acad Sci 800 (1996) 56-67
33. Kiechl S., and Willeit J. The natural course of atherosclerosis. Part II: vascular remodeling. Bruneck Study Group. Arterioscler Thromb Vasc Biol 19 (1999) 1491-1498
34. Baron Y.M., Galea R., and Brincat M. Carotid artery wall changes in estrogen-treated and -untreated postmenopausal women. Obstet Gynecol 91 (1998) 982-986
35. Sumino H., Ichikawa S., Kasama S., et al. Different effects of oral conjugated estrogen and transdermal estradiol on arterial stiffness and vascular inflammatory markers in postmenopausal women. Atherosclerosis 189 (2006) 436-442
36. Fitzpatrick L.A., Ruan M., Anderson J., Moraghan T., and Miller V. Gender-related differences in vascular smooth muscle cell proliferation: implications for prevention of atherosclerosis. Lupus 8 (1999) 397-401
37. Nakamura Y., Suzuki T., Miki Y., et al. Estrogen receptors in atherosclerotic human aorta: inhibition of human vascular smooth muscle cell proliferation by estrogens. Mol Cell Endocrinol 219 (2004) 17-26
38. Staessen J.A., van der Heijden-Spek J.J., Safar M.E., et al. Menopause and the characteristics of the large arteries in a population study. J Hum Hypertens 15 (2001) 511-518
39. 2+ entry mechanisms of arterial vasoconstriction by sex hormones. Clin Exp Pharmacol Physiol 26 (1999) 707-715
40. Minshall R.D., Stanczyk F.Z., Miyagawa K., et al. Ovarian steroid protection against coronary artery hyperreactivity in rhesus monkeys. J Clin Endocrinol Metab 83 (1998) 649-659
41. Egami R., Tanaka Y., Nozaki M., Koera K., Okuma A., and Nakano H. Chronic treatment with 17beta-estradiol increases susceptibility of smooth muscle cells to nitric oxide. Eur J Pharmacol 520 (2005) 142-149
42. McGrath B.P., Liang Y.L., Teede H., Shiel L.M., Cameron J.D., and Dart A. Age-related deterioration in arterial structure and function in postmenopausal women: impact of hormone-replacement therapy. Arterioscler Thromb Vasc Biol 18 (1998) 1149-1156
43. Hsia J., Criqui M.H., Rodabough R.J., et al. Estrogen plus progestin and the risk of peripheral arterial disease: the women's health initiative. Circulation 109 (2004) 620-626
44. Ho J.Y., Chen M.J., Sheu W.H., et al. Differential effects of oral conjugated equine estrogen and transdermal estrogen on atherosclerotic vascular disease risk markers and endothelial function in healthy postmenopausal women. Hum Reprod 21 (2006) 2715-2720
45. Liang Y.L., Teede H., Shiel L.M., et al. Effects of oestrogen and progesterone on age-related changes in arteries of postmenopausal women. Clin Exp Pharmacol Physiol 24 (1997) 457-459
46. Matthews K.A., Kuller L.H., Wing R.R., Meilahn E.N., and Plantinga P. Prior to use of estrogen replacement therapy, are users healthier than non-users?. Am J Epidemiol 143 (1996) 971-978
47. Anderson T.J., Meredith I.T., Charbonneau F., et al. Endothelium-dependent coronary vasomotion relates to the susceptibility of LDL to oxidation in humans. Circulation 93 (1996) 1647-1650