Synthesis of a hypocrellin B-polyamide conjugate as DNA-targeting photosensitizer

Chinese Chemical Letters

Volumn 19, Issue 2, 2008, Pages 157-160

  Liu, Yan Yan ^a,b   Xia, Sheng Qin ^a   Zeng, Zhang Hua ^a,b   Qiao, Rui ^a,b   Wang, Xue Song ^a   Zhang, Bao Wen ^a  

^a TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

DNA affinity; Groove binding; Hypocrellin; Polyamide

Indexed keywords

EID: 38649139341     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2007.11.013     Document Type: Article

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28. 1H NMR (400 MHz, CDCl3, δ ppm): 16.61 (s, 1H), 16.37 (s, 1H), 9.80 (s, 1H), 7.73 (d, 1H, J = 8.6 Hz), 7.40 (d, 1H, J = 1.9 Hz), 7.05 (d, 1H, J = 2.0 Hz), 6.92 (d, 1H, J = 8.6 Hz), 6.44 (s, 2H), 6.08 (s, 1H), 4.25 (t, 2H, J = 5.4 Hz), 4.14 (s, 3H), 4.12 (s, 3H), 4.09 (s, 3H), 3.98(s, 3H), 3.96 (s, 3H), 3.67 (s, 1H), 3.49 (t, 2H, J = 5.9 Hz), 2.61 (s, 1H), 2.32 (t, 2H, J = 7.4 Hz), 2.10 (s, 3H), 1.87-1.97 (m, 2H), 1.60-1.65 (m, 6H), 1.43 (m, 2H). MALDI-TOF MS: m/z = 916 (M+).