A multi-function compact small-animal imaging system incorporating multipinhole standard and helical SPECT and parallel-hole SPECT

IEEE Nuclear Science Symposium Conference Record

Volumn 4, Issue , 2006, Pages 2430-2438

  Qian, Jianguo ^a,b   Bradley, Eric L ^b   Majewski, Stan ^c   Popov, Vladimir ^c   Saha, Margaret S ^a,b   Smith, Mark F ^a,c   Weisenberger, Andrew G ^c   Welsh, Robert E ^b  

^a IEEE

^b Dept of Economics and Thomas Jefferson Program in Public Policy at the College of William and Mary   (United States)

^c THOMAS JEFFERSON NATIONAL ACCELERATOR FACILITY   (United States)

Author keywords

Helical; Multipinhole; Single photon emission computed tomography (SPECT); Small animal imaging

Indexed keywords

IMAGE ANALYSIS; PIXELS; SEMICONDUCTOR DETECTORS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

MULTIPINHOLE; SMALL ANIMAL IMAGING;

ANIMALS;

EID: 38649138012     PISSN: 10957863     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NSSMIC.2006.354403     Document Type: Conference Paper

References (42)

1. N.U. Schramm, C. Lackas, J. W. Hoppin, T. Schurrat, M. Behe, U. Engeland, and T. M. Behr, "On the Performance of Two Multi-Pinhole SPECT Systems for Small Animal Research," Conf. Rec. 2004 Nuclear Science Symp. Medical Imaging Conf, 2005
2. N.U. Schramm, M. Schipper, T. Schurrat, M. Behe, H. Alike, U. Engeland, G. Ebel, and T.M. Behr, "Performance of a multi-pinhole animal SPECT," Conf. Rec. 2003 Nuclear Science Symp. Medical Imaging Conf., 2004.
3. N.U. Schramm, G. Ebel, U. Engeland, T. Schurrat, M. Behe, and T.M. Behr, "High-resolution SPECT using multipinhole collimation," IEEE Trans. Nucl Sci., vol.50, no.3, pp.315-320, 2003.
4. N.U. Schramm, G. Ebel, U. Engeland, T. Schurrat, M. Behe, and T.M. Behr, "High-resolution SPECT using multi-pinhole collimation," Conf. Rec. 2002 Nuclear Science Symp. Medical Imaging Conf., 2003.
5. N.U. Schramm, A. Wirrwar, and H. Halling, "Development of a multi-pinhole detector for high-sensitivity SPECT imaging," Conf. Rec. 2001 Nuclear Science Symp. Medical Imaging Conf, 2002.
6. C. Lackas, N.U. Schramm, J.W. Hoppiri, and H. Halling, "On the development of a high-resolution multi-pinhole SPECT/CT," Conf. Rec. 2004 Nuclear Science Symp. Medical Imaging Conf., 2005.
7. C. Lackas, N.U. Schramm, J.W. Hoppin, U. Engeland, A. Wirrwar, and H. Hailing, "T-SPECT: a novel imaging technique for small animal research," IEEE Trans. Nucl. Sci., vol.52, no.1, pp.181-7, 2005.
8. C. Lackas, N.U. Schramm, U. Engeland, and H. Hailing, "T-SPECT: a novel imaging technique for small animal research," Conf. Rec. 2003 Nuclear Science Symp. Medical Imaging Conf, 2004.
9. Bioscan Inc., Washington, DC 20007
10. S.R. Meikle, P. Kench, R. Wojcik, M.F. Smith, A.G. Weisenberger, S. Majewski, M. Lerch, and A.B. Rosenfeld, "Performance evaluation of a multipinhole small animal SPECT system," Conf. Rec. 2003 Nuclear Science Symp. Medical Imaging Conf., 2004.
11. S.R. Meikle, R. Wojcik, A.G. Weisenberger, M.F. Smith, S. Majewski, P. Kench, S. Eberl, R.R. Fulton, M. Lerch, and A.B. Rosenfeld, "CoALA-SPECT: a coded aperture laboratory animal SPECT system for pre clinical imaging," Conf. Rec. 2002 Nuclear Science Symp. Medical Imaging Conf, 2003.
12. S.R. Meikle, P. Kench, A.G. Weisenberger, R. Wojcik, M.F. Smith, S. Majewski, S. Eberl, R.R. Fulton, A.B. Rosenfeld, and M.J. Fulham, "A prototype coded aperture detector for small animal SPECT," IEEE Trans. Nucl. Sci., vol.49, pp.2167-2171, 2002.
13. F. J. Beekman, F. van der Have, B. Vastenhouw, A. J. A. van der Linden, P. P. van Rijk, J. P. H. Burbach, and M. P. Smidt, "U-SPECT-I: Anovel system for submillimeter-resolution tomography with radiolabeled molecules in mice," J. Nucl. Med., vol.46, pp.1194-1200, 2005.
14. F. J. Beekman and B. Vastenhouw, "Design and simulation of a highresolution stationary SPECT system for small animals," Phys. Med. Biol, vol.49, pp.4579 - 4592, 2004.
15. F. J. Beekman, Presentation at 2006 Academy of Molecular Imaging Conf, Orlando, FL.
16. A.L. Goertzen, D.W. Jones, J. Seidel, L. King, and M.V. Green, "First results from the high-resolution mouseSPECT annular scintillation camera," IEEE Trans. Med. Imag., vol.24, no.7, pp.863-867, 2005
17. T.E. Peterson, S. Shokouhi, L.R. Furenlid, and D.W. Wilson, "Multi-pinhole SPECT imaging with silicon strip detectors," Conf. Rec. 2005 Nuclear Science Symp. Medical Imaging Conf., 2006.
18. G.S.P. Mok, Y. Wang, and B.M.W. Tsui, "Design of a novel pinhole collimator system for SPECT imaging of small animals with different sizes," Conf. Rec. 2005 Nuclear Science Symp. Medical Imaging Conf., 2006.
19. T. Funk, P. Despres, and W.C. Barber, "A multipinhole small animal SPECT system with submillimeter spatial resolution," Med. Phys., vol. 33, 2006
20. N.H. Patil and S.D. Metzler, "Step-and-shoot versus continuous helical pinhole SPECT for improved axial resolution," Conf. Rec. 2004 Nuclear Science Symp. Medical Imaging Conf, 2005.
21. S.D. Metzler, R.J. Jaszczak, K.L. Greer, and J.E. Bowsher, "Angular-dependent axial-shift correction for pinhole SPECT," Conf. Rec. 2005 Nuclear Science Symp. Medical Imaging Conf, 2006.
22. S.D. Metzler, R.J. Jaszczak, N.H. Patil, S. Vemulapalli, G. Akabani, and B.B. Chin, "Molecular imaging of small animals with a triple-head SPECT system using pinhole collimation," IEEE Trans. Med. Imag., vol.24, no.7, pp.853-862, 2005.
23. S.D. Metzler, K.L. Greer, and R.J. Jaszczak, "Determination of mechanical and electronics shifts for pinhole SPECT using a single point source," IEEE Trans. Med. Imag., vol.24, no. 3, pp.361-370, 2005.
24. S.D. Metzler, K.L. Greer, K. Bobkov, and R.J. Jaszczak, "Laser alignment system for helical pinhole SPECT," IEEE Trans. Nucl. Sci., vol.51, no.3, pp.603-610, 2004.
25. S.D. Metzler, K.L. Greer, and R.J. Jaszczak, "Helical pinhole SPECT for small-animal imaging: a method for addressing sampling completeness," IEEE Trans. Nucl. Sci., vol.50, no.5, pp.1575-1583, 2003.
26. M. Sun; E.W. Izaguirre, T. Funk, A.B. Hwang, J. Carver, S. Thompson, B.E. Part, K.B. Parnham, T. Vandehei, J. Li, and B.H. Hasegawa, "A small animal helical SPECT scanner," Conf Rec. 2005 Nuclear Science Symp. Medical Imaging Conf, 2006.
27. A.B. Hwang, K. Iwata, A.E. Sakdinawat, M.C. Wu, and B.H. Hasegawa, "Gantry specifications for a dual modality imaging system for small animals," Conf. Rec. 2002 Nuclear Science Symp. Medical Imaging Conf, 2003.
28. G.L. Zeng, G.T. Gullberg, P.E. Christian, and D. Gagnon, "Cone-beam iterative reconstruction of a segment of a long object," IEEE Trans. Nucl. Sci., vol.49, no.1, pp.3741, 2002.
29. G.L. Zeng, G.T. Gullberg, P.E. Christian, D. Gagnon, and C.H. Tung, "Asymmetric cone-beam transmission tomography," IEEE Trans. Nucl. Sci., vol.48, no. 1, pp.117-124, 2001.
30. G.L. Zeng and G.T. Gullberg, "Helical SPECT using axially truncated data," IEEE Trans. Nucl Sci., vol.46, no.6, pp.2111-2118, 1999.
31. W. Hammond, E.L. Bradley, R.E. Welsh, J. Qian, A.G. Weisenberger, M.F. Smith, and M. S. Saha. "A gamma camera re-evaluation of potassium iodide blocking efficiency in mice," Health Physics, in press.
32. E.L. Bradley, J. Cella, S. Majewski, V. Popov, J. Qian, M.S. Saha, M.F. Smith, A.G. Weisenberger, and R.E. Welsh. "A compact gamma camera for biological imaging. IEEE Trans. Nucl. Sci., vol. 53, no. 1, pp. 59-65, 2006
33. E.L. Bradley, J. Cella, S. Majewski, V. Popov, J. Qian, M.S. Saha, M.F. Smith, A.G. Weisenberger, and R.E. Welsh, "A 'mouse-sized' gamma camera for biological imaging," Conf. Rec. 2004 Nuclear Science Symp. Medical Imaging Conf., M5-94, 2005.
34. 125I SPECT Imaging of Small Animals with Pinhole and Parallel Collimation," Conf. Rec. 2003 Nuclear Science Symp. Medical Imaging Conf., M7-42, 2004.
35. M.S. Saha, E.L. Bradley, P. Brewer, K.K. Gleason, B. Kross, S. Majewski, V. Popov, J. Qian, A. Ranck, K. Smith, M.F. Smith, A.G. Weisenberger, R. Wojcik, and R.E. Welsh, "Incorporation of a fluoroscopic x-ray modality in a small animal imaging system," IEEE Trans. Nucl. Sci., vol. 50, no. 3, pp. 333-338, 2003
36. A.G. Weisenberger, R. Wojcik, E.L. Bradley, P. Brewer, S. Majewski, J. Qian, A.E. Ranck, M.S. Saha, K. Smith, M.F. Smith, and R.E. Welsh, "SPECT-CT system for small animal imaging," IEEE Trans. Nucl. Sci., vol. 50, no. 1, pp. 74-79, 2003.
37. 125Iodine-Labeled insulin during the development of streptozotocin-in-ducedhyperglycemia in the C57bl/6J mouse with a dedicated gamma imager," in Proc. High Resolution Imaging in Small Animals: Instrumentation, Applications and Animal Handling Conf., Rockville, MD, Sept. 9-11, 2001
38. P.J. Green, "Bayesian reconstruction from emission tomography data using a modified EM algorithm," IEEE Trans. Med. Imag., vol.9, pp.84-93, 1990
39. J. Li, R.J. Jaszczak, and R.E. Coleman, "Maximum likelihood reconstruction for pinhole SPECT with a displaced center-of-rotation," IEEE Trans. Med. Imag., vol. 14, pp. 407-409, 1995
40. R.L. Siddon, "Fast calculation of the exact radiological path for a three-dimensional CT array," Med. Phys., vol. 12, pp.252-255, 1985
41. E.L. Keller, "Optimum dimensions of parallel-hole, multi-aperture collimators for gamma-ray cameras," J. Nucl. Med., vol.9, pp.233-235, 1968.
42. M.F. Smith, S. Majewski, and A.G. Weisenberger, "Optimizing pinhole and parallel hole collimation for scintimammography with compact pixellated detectors," IEEE Trans. Nucl. Sci., vol.50, pp.321-326, 2003.