A compact gamma camera for biological imaging

IEEE Transactions on Nuclear Science

Volumn 53, Issue 1, 2006, Pages 59-65

  Bradley, Eric L ^b   Cella, Julie ^b   Majewski, Stan ^c   Popov, Vladimir ^c   Qian, Jianguo ^b   Saha, Margaret S ^a,b   Smith, Mark F ^a,c   Weisenberger, Andrew G ^c   Welsh, Robert E ^b  

^a IEEE

^b The College of William and Mary   (United States)

^c THOMAS JEFFERSON NATIONAL ACCELERATOR FACILITY   (United States)

Author keywords

Biomedical imaging; Scintillation detectors; Single photon emission computed tomography; Small animal imaging

Indexed keywords

COMPUTERIZED TOMOGRAPHY; IMAGING SYSTEMS; OPTICAL COLLIMATORS; PHOTOMULTIPLIERS; POSITRON EMISSION TOMOGRAPHY; SCINTILLATION COUNTERS;

PARALLEL-HOLE COLLIMATOR; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SMALL ANIMAL IMAGING;

BIOMEDICAL ENGINEERING;

EID: 33645658294     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNS.2005.862977     Document Type: Article

References (35)

1. P. D. Acton and H. F. Kung, "Small animal imagining with high resolution single photon emission tomography," Nucl. Med. Biol., vol. 30, pp. 889-895, 2003.
2. G. Choy, P. Choyke, and S. K. Libutti, "Current advances in molecular imaging: Noninvasive in vivo bioluminescent and fluorescent optical imaging in cancer research," Mol. Imag., vol. 2, pp. 303-312, 2003.
3. M. Doubrovin, O. Sergampva, P. Mayer-Kuckuk, V. Ponomarev, and R. Blasberg, "Multimodality in vivo molecular-genetic imaging," Bioconjug. Chem., vol. 15, pp. 1376-1388, 2004.
4. H. R. Herschman, "Noninvasive imaging of reporter gene expression in living subjects," Adv. Cancer Res., vol. 92, pp. 29-80, 2004.
5. S. Nikolaus, A. Wirrwar, C. Antke, S. Arkian, N. Schramm, H. W. Muller, and R. Larisch, "Quantitation of dopamine transporter blockade by methylphenidate," Eur. J. Nucl. Mol. Imaging. Oct. 12, 2004.
6. E. E. Graves, R. Weissleder, and V. Ntaizchachristos, "Fluorescence molecular imaging of small animal tumor models," Curr. Mol. Med., vol. 4, pp. 419-430, 2004.
7. Y. Yang, Y. C. Tai, S. Siegel, D. F. Newport, B. Bai, Q. Li, R. M. Leahy, and S. R. Cherry, "Optimization and performance evaluation of the microPETII scanner for in vivo small-animal imaging," Phys. Med. Biol., vol. 49, pp. 2527-2545, 2004.
8. E. L. Ritman, "Micro-computed tomography-current status and developments," Annu. Rev. Biomed. Eng., vol. 6, pp. 185-208, 2004.
9. H8500 PSPMT, Hamamatsu, Inc., Hamamatsu City, Japan.
10. R. Pani, R. Pellegrini, M. N. Cinti, C. Trotta, G. Trotta, F. Garibaldi, R. Scafe, and A. Del Guerra, "Flat panel PMT for photon emission imaging," in Proc. 10th Symp. Radialion Measurements Applications, 2003.
11. R. Pani, R. Pellegrini, M. N. Cinti, C. Trotta, G. Trotta, R. Scafe, L. D'Addio, G. Iurlaro, L. Montani, P. Bennati, S. Ridolfi, F. Cusanno, and F. Garibaldi, "Factors affecting flat panel PMT calibration for gamma ray imaging," in Proc. 2002 IEEE Nuclear Science Symp. Conf. Rec., 2003.
12. R. Engels, U. Clemens, G. Kemmerling, and J. Schelten, "High spatial resolution scintillation detector based on the H8500 photomultiplier," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
13. S. Korpar, I. Adachi, S. Fratina. I. Iijima, R. Islubashi, H. Kawai, P. Krizan, T. Matsumoto, S. Ogawa, R. Pestotnik, S. Saitoh, T. Seki, I. Sumiyoshi, K. Suzuki, T. Tahata, Y. Uchida, and Y. Unno, "Tests of a proximity focusing RICH with aerogel radiator and flat-panel multianode PMT's (H8500)," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
14. C. Lerche, J. M. Benlloch, F. Sanchez, N. Pavon, E. N. Gimenez, M. Gimenez, M. Fernandez, J. Cerda, J. Martinez, and A. Sebastia, "Depth of interaction measurement in gamma ray imaging detectors with continuous scintillation crystals," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
15. P. D. Olcott, J. A. Talcott, C. S. Levin, F. Habte, and A. M. K. Foudray, "Compact readout electronics for position sensitive photomultiplier tubes," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
16. V. Popov, S. Majewski, and A. G. Weisenberger, "Readout electronics for multianode photomultiplier tubes with pad matrix anode layout," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
17. A. V. Stolin, M. B. Williams, B. K. Kundu, S. Majewski, V. Popov, and A. G. Weisenberger, "Characterization of imaging gamma detectors for use in small animal SPECT," in Proc. 2003 IEEE Nuclear Science. Symp. Conf. Rec., 2004.
18. N. C. Rouze, M. Schmand, S. Siegel, and G. D. Hutchins, "Design of a small animal PET imaging system with 1 microliter volume resolution," in Proc. 2003 IEEE Nuclear Science Symp. Conf. Rec., 2004.
19. N. C. Rouze, M. Schmand, S. Siegel, and G. D. Hutchins, "Design of a small animal PET imaging system with 1 microliter volume resolution," IEEE Trans. Nucl. Sci., vol. 51. no. 3, pp. 757-763, Jun. 2004.
20. Bicron/St. Gobain Inc., Cleveland, OH, Paris, France.
21. TECOMET, Inc., Woburn, MA.
22. A. G. Weisenberger, E. Bradley, S. Majewski, and M. Saha, "Development of a novel radiation imaging detector system for in vivo gene imaging in small animal studies," IEEE Trans. Nucl. Sci., vol. 145, no. 3, pp. 1743-1749, Jun. 1998.
23. A. G. Weisenberger, E. Bradley, S. Majewski, and M. Saha, "A CsI(Na) based radiation detector for high resolution imaging studies using iodine 125 in small animal research." in Proc. SPIE, vol. 3115, 1997, pp. 254-262.
24. A. G. Weisenberger, B. Kross, S. Majewski, R. Wojcik, E. Bradley, and M. Saha, "Design features and performance of a CsI(Na) array based gamma camera for small animal gene research," IEEE Trans. Nucl. Sci., vol. 45, no. 6. pp. 3053-3058. Dec. 1998.
25. R. E. Welsh, E. L. Bradley, B. Kross, S. Majewski, V. Popov, A. Ranck, M. S. Saha, K. Smith, M. F. Smith, A. G. Weisenberger, and R. Wojcik, "An economical dual-modality small animal imaging system with application to studies of diabetes," in Proc. Conf. Rec. IEEE Nuclear Science Symp. Medical Imaging. 2001.
26. A. G. Weisenberger, R. Wojcik. E. L. Bradley, S. Majewski, J. Qian, A. Ranck, M. S. Saha, K. Smith, M. F. Smith, and R. E. Welsh, "SPECT-CT system for small animal imaging." IEEE Trans. Nucl. Sci., vol. 50, no. 1, pp. 74-79, Feb. 2003.
27. M. S. Saha, E. L. Bradley, P. Brewer, K. K. Gleason, B. Kross, S. Majewski, V. Popov, J. Qian, A. Ranck, K. Smith, M. F. Smith, A. G. Weisenberger, and R. Wojcik, "Incorporation of a fluoroscopic X-ray modality in a small animal imaging system," IEEE Trans Nucl Sci., vol. 50, no. 3, pp. 333-338, Jun. 2003.
28. M. F. Smith, S. Majewski, and A. G. Weisenberger, "Optimizing pinhole and parallel hole collimation for scintimammography with compact pixellated detectors," IEEE Trans Nucl Sci., vol. 50, no. 3, pp. 321-326, Jun. 2003.
29. Composiflex, Inc., Erie, PA, 16509.
30. RX-688 Optical Coupling Grease. Beachwood, OH, 44122: Rexon Inc.
31. Sparrow Corp., Port Orange, FL, 32 128.
32. E. L. Keller, "Optimum dimensions of parallel-hole, multi-aperture collimators for gamma-ray cameras," J. Nucl. Med., vol. 9. pp. 233-235, 1968.
33. J. Y. Cho, R. Leveille, R. Kao, B. Rousset, A. F. Parlow, W. E. Burak Jr., E. L. Mazzaferri, and S. M. Jhiang, "Hormonal regulation of radioiodide uptake activity and Na+/I- symporter expression in mammary glands," J. Clin. Endocrinol. Metab., vol. 85, pp. 2936-2943, 2000.
34. B. Perron, A. M. Rodriguez, G. Leblanc, and T. Fourcher, "Cloning of the mouse sodium iodide symporter and its expression in the mammary gland and other tissues." J. Endocrinol., vol. 170, pp. 185-196, 2001.
35. S. Meikle, private communication personal communication.