One-pot, three-component route to 2H-indazolo[2,1-b]phthalazine-triones

Tetrahedron

Volumn 64, Issue 10, 2008, Pages 2375-2378

  Sayyafi, Maryam ^a   Seyyedhamzeh, Mozhdeh ^a   Khavasi, Hamid Reza ^a   Bazgir, Ayoob ^a  

^a SHAHID BEHESHTI UNIVERSITY   (Iran)

Author keywords

Dimedone; Indazolophtalazine; One pot reaction; Phthalhydrazide

Indexed keywords

2H INDAZOLO[2,1 B]PHTHALAZINE 1,6,11(13H) TRIONE; 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ALDEHYDE; HYDRAZIDE DERIVATIVE; PHTHALAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ONE POT SYNTHESIS; POLYMERIZATION; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME;

EID: 38649136593     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.01.006     Document Type: Article

References (22)

1. Gerencser J., Dormon G., and Darvas F. QSAR Comb. Sci. (2006) 439
2. Ramon D.J., and Yus M. Angew. Chem., Int. Ed. 44 (2005) 1602
3. Hulme C., and Gore V. Curr. Med. Chem. 10 (2003) 51
4. Aĺ-Assar F., Zelenin K.N., Lesiovskaya E.E., Bezhan I.P., and Chakchir B.A. Pharm. Chem. J. 36 (2002) 598
5. Jain R.P., and Vederas J.C. Bioorg. Med. Chem. Lett. 14 (2004) 3655
6. Carling R.W., Moore K.W., Street L.J., Wild D., Isted C., Leeson P.D., Thomas S., O'Conner D., McKernan R.M., Quirk K., Cook S.M., Atack J.R., Waftord K.A., Thompson S.A., Dawson G.R., Ferris P., and Castro J.L. J. Med. Chem. 47 (2004) 1807
7. Grasso S., DeSarro G., Micale N., Zappala M., Puia G., Baraldi M., and Demicheli C. J. Med. Chem. 43 (2000) 2851
8. Nomoto Y., Obase H., Takai H., Teranishi M., Nakamura J., and Kubo K. Chem. Pharm. Bull. (Tokyo) 38 (1990) 2179
9. Watanabe N., Kabasawa Y., Takase Y., Matsukura M., Miyazaki K., Ishihara H., Kodama K., and Adachi H. J. Med. Chem. 41 (1998) 3367
10. Sheradsky T., and Moshenberg R. J. Org. Chem. 51 (1986) 3123
11. Heine H.W., Baclawski L.M., Bonser S.M., and Wachob G.D. J. Org. Chem. 41 (1976) 3229
12. Ramtohup Y.K., James M.N.G., and Vederas J.C. J. Org. Chem. 67 (2002) 3169
13. Liu L.P., Lu J.M., and Shi M. Org. Lett. 9 (2007) 1303
14. Csampai A., Kormendy K., and Ruff F. Tetrahedron 47 (1991) 4457
15. Amarasekara A.S., and Chandrasekara S. Org. Lett. 4 (2002) 773
16. Hwang J.Y., Choi H.S., and Gong Y.D. Tetrahedron Lett. 46 (2005) 3107
17. Quiroga J., Mejia D., Insuasty B., Abonia R., Nogueras M., Sanchez A., Cobo J., and Low J.N. Tetrahedron 57 (2001) 6947
18. Quiroga J., Hormaza A., Insuasty B., Ortiz A.J., Sanchez A., and Nogueras M. J. Heterocycl. Chem. 35 (1998) 231
19. Tu S., Fang F., Li T., Zhu S., and Zhang X. J. Heterocycl. Chem. 42 (2005) 707
20. Quiroga J., Insuasty B., Hormaza A., Saitz C., and Jullian C. J. Heterocycl. Chem. 35 (1998) 575
21. Shaabani A., Rahmati A., and Naderi S. Bioorg. Med. Chem. Lett. 15 (2005) 5553
22. 2 values to final R1=0.0756, wR2=0.1396 and S=1.145 with 263 parameters using 5473 independent reflection (θ range=1.68-29.26°). Hydrogen atoms were located from expected geometry and were not refined. Crystallographic data for 4c have been deposited with the Cambridge Crystallographic Data Centre. Copies of the data can be obtained, free of charge, on application to The Director, CCDC 660455, Union Road, Cambridge CB2 1EZ, UK. Fax: +44 1223 336033 or e-mail: deposit@ccdc.cam.ac.uk.