Mammalian Ste20-like protein kinase 3 mediates trophoblast apoptosis in spontaneous delivery

Apoptosis

Volumn 13, Issue 2, 2008, Pages 283-294

  Wu, Hung Yi ^a   Lin, Chia Ying ^a   Lin, Tze Yi ^b   Chen, Tai Chang ^b   Yuan, Chiun Jye ^a  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b Hsinchu General Hospital   (Taiwan)

Author keywords

Apoptosis; Mst3; Oxidative stress; Parturition; Placenta; Trophoblasts

Indexed keywords

ANGIOTENSIN II; CASPASE 3; HYDROGEN PEROXIDE; MAMMALIAN STE20 LIKE PROTEIN KINASE 3; OXYTOCIN; PROSTAGLANDIN E1; PROTEIN KINASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CESAREAN SECTION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABOR PAIN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPONTANEOUS PLACENTAL DELIVERY; TROPHOBLAST;

APOPTOSIS; CASPASE 3; CELL LINE; DELIVERY, OBSTETRIC; FEMALE; HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, THIRD; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TROPHOBLASTS;

MAMMALIA;

EID: 38649127572     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0161-x     Document Type: Article

References (49)

1. Rama S, Suresh Y, Rao AJ (2001) Regulation of telomerase during human placental differentiation: a role for TGFbeta1. Mol Cell Endocrinol 182:233-248
2. Morrish DW, Dakour J, Li H (1998) Functional regulation of human trophoblast differentiation. J Reprod Immunol 39:179-195
3. Red-Horse K, Zhou Y, Genbacev O et al (2004) Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. J Clin Invest 114:744-754
4. Huppertz B, Kingdom JC (2004) Apoptosis in the trophoblast - role of apoptosis in placental morphogenesis. J Soc Gynecol Investig 11:353-362
5. Rama S, Rao AJ (2003) Regulation of growth and function of the human placenta. Mol Cell Biochem 253:263-268
6. Austgulen R, Chedwick L, Vogt Isaksen C, Vatten L, Craven C (2002) Trophoblast apoptosis in human placenta at term as detected by expression of a cytokeratin 18 degradation product of caspase. Arch Pathol Lab Med 126:1480-1486
7. Axt R, Meyberg R, Mink D, Wasemann C, Reitnauer K, Schmidt W (1999) Immunohistochemical detection of apoptosis in the human term and post-term placenta. Clin Exp Obstet Gynecol 26:56-59
8. Smith SC, Baker PN, Symonds EM (1997) Placental apoptosis in normal human pregnancy. J Obstet Gynecol 177:57-65
9. Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257
10. Runic R, Lockwood CJ, LaChapelle L et al (1998) Apoptosis and Fas expression in human fetal membranes. J Clin Endocrinol Metab 83:660-666
11. Balkundi DR, Hanna N, Hileb M, Dougherty J, Sharma S (2000) Labor-associated changes in Fas ligand expression and function in human placenta. Pediatr Res 47:301-308
12. Fukushima K, Miyamoto S, Komatsu H et al (2003) TNFalpha-induced apoptosis and integrin switching in human extravillous trophoblast cell line. Biol Reprod 68:1771-1778
13. Ohyama K, Yuan B, Bessho T, Yamakawa T (2001) Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents. Eur J Biochem 268:6182-6189
14. McAleer MF, Tuan RS (2001) Metallothionein protects against severe oxidative stress-induced apoptosis of human trophoblastic cells. In Vitr Mol Toxicol 14:219-231
15. Ray SD, Lam TS, Rotollo JA et al (2004) Oxidative stress is the master operator of drug and chemically-induced programmed and unprogrammed cell death: Implications of natural antioxidants in vivo. Biofactors 21:223-232
16. Ohyama K, Oka K, Emura A et al (1998) Suppression of apoptotic cell death progressed in vitro with incubation of the chorion laeve tissues of human fetal membrane by glucocorticoid. Biol Pharm Bull 21:1024-1029
17. Ratts VS, Tao XJ, Webster CB et al (2000) Expression of BCL-2, BAX and BAK in the trophoblast layer of the term human placenta: a unique model of apoptosis within a syncytium. Placenta 21:361-366
18. Qiao S, Nagasaka T, Harada T, Nakashima N (1998) p53, Bax and Bcl-2 expression, and apoptosis in gestational trophoblast of complete hydatidiform mole. Placenta 19:361-369
19. Huppertz B, Frank HG, Kingdom JC, Reister F, Kaufmann P (1998) Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem Cell Biol 110:495-508
20. Smith SC, Leung TN, To KF, Baker PN (2000) Apoptosis is a rare event in first-trimester placental tissue. Am J Obstet Gynecol 183:697-699
21. Allaire AD, Ballenger KA, Wells SR, McMahon MJ, Lessey BA (2000) Placental apoptosis in preeclampsia. Obstet Gynecol 96:271-276
22. Ishihara N, Matsuo H, Murakoshi H, Laoag-Fernandez JB, Samoto T, Maruo T (2002) Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol 186:158-166
23. Solomon CG, Seely EW (2004) Preeclampsia - searching for the cause. N Engl J Med 350:641-642
24. Schinkmann K, Blenis J (1997) Cloning and characterization of a human STE20-like protein kinase with unusual cofactor requirements. J Biol Chem 272:28695-28703
25. Stegert MR, Hergovich A, Tamaskovic R, Bichsel SJ, Hemmings BA (2005) Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3. Mol Cell Biol 25:11019-11029
26. Lu TJ, Lai WY, Huang CY et al (2006) Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. J Biol Chem 281:38405-38417
27. Huang CY, Wu YM, Hsu CY et al (2002) Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis. J Biol Chem 277:34367-34374
28. Lee WS, Hsu CY, Wang PL, Huang CY, Chang CH, Yuan CJ (2004) Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3. FEBS Lett 572:41-45
29. van de Wetering M, Oving I, Muncan V et al (2003) Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO Rep 4:609-615
30. Song J, Lu YC, Yokoyama K, Rossi J, Chiu R (2004) Cyclophilin A is required for retinoic acid-induced neuronal differentiation in p19 cells. J Biol Chem 279:24414-24419
31. Fainaru O, Almog B, Pinchuk I, Kupferminc MJ, Lichtenberg D, Many A (2002) Active labour is associated with increased oxidisibility of serum lipids ex vivo. Bjog 109:938-941
32. Many A, Roberts JM (1997) Increased xanthine oxidase during labour-implications for oxidative stress. Placenta 18:725-726
33. Mocatta TJ, Winterbourn CC, Inder TE, Darlow BA (2004) The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma. Free Radic Res 38:185-191
34. Pressman EK, Cavanaugh JL, Mingione M, Norkus EP, Woods JR (2003) Effects of maternal antioxidant supplementation on maternal and fetal antioxidant levels: a randomized, double-blind study. Am J Obstet Gynecol 189:1720-1725
35. Yaacobi N, Ohel G, Hochman A (1999) Reactive oxygen species in the process of labor. Arch Gynecol Obstet 263:23-24
36. Ellis RE, Yuan JY, Horvitz HR (1991) Mechanisms and functions of cell death. Annu Rev Cell Biol 7:663-698
37. Soengas MS, Alarcon RM, Yoshida H et al (1999) Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284:156-159
38. Thornberry NA, Lazebnik Y (1998) Caspases: enemies within. Science 281:1312-1316
39. Di Santo S, Malek A, Sager R, Andres AC, Schneider H (2003) Trophoblast viability in perfused term placental tissue and explant cultures limited to 7-24 hours. Placenta 24:882-894
40. Genbacev O, Schubach SA, Miller RK (1992) Villous culture of first trimester human placenta - model to study extravillous trophoblast (EVT) differentiation. Placenta 13:439-461
41. Husslein P (1984) The importance of oxytocin and prostaglandins to the mechanism of labor in humans. Wien Klin Wochenschr Suppl 155:1-32
42. Kisch ES, Jaffe A, Knoll E, Stern N (1997) Role of the lipoxygenase pathway in angiotensin II-induced vasoconstriction in the human placenta. Hypertension 29:796-801
43. Shen HM, Liu ZG (2006) JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic Biol Med 40:928-939
44. Wisdom SJ, Wilson R, McKillop JH, Walker JJ (1991) Antioxidant systems in normal pregnancy and in pregnancy-induced hypertension. Am J Obstet Gynecol 165:1701-1704
45. Black S, Yu H, Lee J, Sachchithananthan M, Medcalf RL (2001) Physiologic concentrations of magnesium and placental apoptosis: prevention by antioxidants. Obstet Gynecol 98:319-324
46. Roberts JM (2004) Preeclampsia: what we know and what we do not know. Semin Perinatol 24:24-28
47. Jauniaux E, Burton GJ (2005) Pathophysiology of histological changes in early pregnancy loss. Placenta 26:114-123
48. Wall PD, Pressman EK, Woods JR, Jr (2002) Preterm premature rupture of the membranes and antioxidants: the free radical connection. J Perinat Med 30:447-457
49. Takagi Y, Nikaido T, Toki T et al (2004) Levels of oxidative stress and redox-related molecules in the placenta in preeclampsia and fetal growth restriction. Virchows Arch 444:49-55