Tetrahydrobiopterin protects phenylalanine hydroxylase activity in vivo: Implications for tetrahydrobiopterin-responsive hyperphenylalaninemia

FEBS Letters

Volumn 577, Issue 3, 2004, Pages 507-511

  Thöny, Beat ^a   Ding, Zhaobing ^a   Martínez, Aurora ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF BERGEN   (Norway)

Author keywords

Chaperon; Gene expression; Hepatic phenylalanine hydroxylase; Hyperphenylalaninemia; Phenylketonuria; Tetrahydrobiopterin

Indexed keywords

CHAPERONE; LIVER ENZYME; MESSENGER RNA; PHENYLALANINE 4 MONOOXYGENASE; TETRAHYDROBIOPTERIN;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME REGULATION; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC STABILITY; GENETIC TRANSCRIPTION; HYPERPHENYLALANINEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION; TRANSGENIC MOUSE; WILD TYPE;

AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; ANIMALS, NEWBORN; BIOPTERIN; BLOTTING, WESTERN; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, RECESSIVE; HETEROZYGOTE; HUMANS; KINETICS; LIVER; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHENYLKETONURIAS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

MUS MUSCULUS;

EID: 8844256618     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.10.056     Document Type: Article

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