Functionally important residues tyrosine-171 and serine-158 in sepiapterin reductase

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1431, Issue 2, 1999, Pages 306-314

  Fujimoto, Kengo ^a   Ichinose, Hiroshi ^b   Nagatsu, Toshiharu ^b   Nonaka, Takamasa ^c   Mitsui, Yukio ^c   Katoh, Setsuko ^a  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NAGAOKA UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

Sepiapterin reductase; Short chain dehydrogenase reductase; Site directed mutagenesis; Tetrahydrobiopterin

Indexed keywords

LYSINE; MUTANT PROTEIN; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SEPIAPTERIN; SEPIAPTERIN REDUCTASE; SERINE; TETRAHYDROBIOPTERIN; TYROSINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COENZYME; CONTROLLED STUDY; CRYSTAL STRUCTURE; DELETION MUTANT; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; EXPRESSION VECTOR; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RAT; SITE DIRECTED MUTAGENESIS;

ALCOHOL OXIDOREDUCTASES; ANIMALS; BINDING SITES; BIOPTERIN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ESCHERICHIA COLI; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; RATS; SERINE; TYROSINE;

EID: 0032929053     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00054-0     Document Type: Article

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